2022
Wanted: An endothelial cell targeting atlas for nanotherapeutic delivery in allograft organs
Liburd ST, Shi AA, Pober JS, Tietjen GT. Wanted: An endothelial cell targeting atlas for nanotherapeutic delivery in allograft organs. American Journal Of Transplantation 2022, 22: 1754-1759. PMID: 35373446, PMCID: PMC9651180, DOI: 10.1111/ajt.17050.Peer-Reviewed Original ResearchConceptsNormothermic machine perfusionEndothelial cellsGraft vasculaturePoor outcomePreservation injuryMachine perfusionProfound shortageOrgan assessmentTransplant therapeuticsDonor comorbiditiesAllograft organClinical useOrgansAttractive targetNanotherapeutic deliveryTherapeutic vehiclesCellsTherapeutic deliveryDeliveryComorbiditiesTransplantGraftInjuryPerfusionVasculature
2021
Cardiac allograft vasculopathy: current review and future research directions
Pober JS, Chih S, Kobashigawa J, Madsen JC, Tellides G. Cardiac allograft vasculopathy: current review and future research directions. Cardiovascular Research 2021, 117: 2624-2638. PMID: 34343276, PMCID: PMC8783389, DOI: 10.1093/cvr/cvab259.Peer-Reviewed Original ResearchConceptsCardiac allograft vasculopathyAllograft vasculopathyImmune-mediated vasculopathyLate graft lossGraft lossCardiac transplantationOrgan graftsTransplanted heartsCurrent therapiesVascular remodellingVasculopathyMajor causeCurrent reviewRemodellingTransplantationPathogenesisGraftTherapyPerfusionIncidenceDiagnosisVasculature
2011
Cellular Delivery for Vascularization of Engineered Tissues: Reduction of Contraction by Mural Cells
Andrejecsk J, Trivellas M, Maier C, Pober J, Saltzman W. Cellular Delivery for Vascularization of Engineered Tissues: Reduction of Contraction by Mural Cells. 2011, 1: 1-2. DOI: 10.1109/nebc.2011.5778700.Peer-Reviewed Original ResearchEndothelial cellsReduction of contractionHuman endothelial cellsImmunodeficient miceHuman pericytesEarly perfusionGel contractionMural cellsVascular structuresVascular stabilityPericytesMicrovesselsTissueVascular networkVascularizationCellsContractionFunctional vascular networkDeliverySimultaneous deliveryTransplantationPerfusionMice