1989
Sequestration of virus-specific T cells in the cerebrospinal fluid of a patient with varicella zoster viral meningoencephalitis
Duby A, Weiner H, Benjamin D, Seidman JG, Hafler D. Sequestration of virus-specific T cells in the cerebrospinal fluid of a patient with varicella zoster viral meningoencephalitis. Journal Of Neuroimmunology 1989, 22: 63-68. PMID: 2465314, DOI: 10.1016/0165-5728(89)90010-6.Peer-Reviewed Original ResearchConceptsT cell clonesVirus-specific T cellsT cellsCerebrospinal fluidViral meningoencephalitisImmune responseViral infectionHerpes zoster viral infectionAntigen-specific T cellsT-cell receptor beta-chain gene rearrangementBeta-chain gene rearrangementsT cell responsesPatient's cerebrospinal fluidSecondary immune responseT-cell antigen receptor beta-chain geneBeta-chain geneMyelin basic proteinVZV meningoencephalitisMumps virusMeningoencephalitisPatientsClonal expansionGene rearrangementsBlot analysisInfection
1985
Phenotypic and functional analysis of T cells cloned directly from the blood and cerebrospinal fluid of patients with multiple sclerosis
Hafler D, Buchsbaum M, Johnson D, Weiner H. Phenotypic and functional analysis of T cells cloned directly from the blood and cerebrospinal fluid of patients with multiple sclerosis. Annals Of Neurology 1985, 18: 451-458. PMID: 2416267, DOI: 10.1002/ana.410180407.Peer-Reviewed Original ResearchConceptsMultiple sclerosisBlood of patientsT cellsMyelin basic proteinCerebrospinal fluid lymphocytesT-cell abnormalitiesCSF of patientsAntigen-specific cellsIndividual T cellsBasic proteinSuppressor cellsViral meningoencephalitisStimulating lymphocytesInterleukin-2Antigen reactivityCell abnormalitiesCerebrospinal fluidSingle cell clonal analysisPatientsT8 populationWhite matterBloodCSFSclerosisLymphocytes