Craig B. Wilen, MD, PhD
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Biography
Dr. Wilen is an Associate Professor in Laboratory Medicine and Immunobiology and is focused on the host-pathogen interactions of RNA viruses including coronavirus and norovirus. Dr. Wilen received his A.B in Biology and Economics at Washington University in St. Louis, his MD and PhD from the University of Pennsylvania. His residency training was in clinical pathology at Barnes-Jewish Hospital in St. Louis, MO. His postdoctoral studies were conducted in the laboratory of Herbert "Skip" Virgin at Washington University School of Medicine where he studied the pathogenesis of norovirus, the leading cause of acute gastroenteritis. Dr. Wilen discovered CD300lf as the first receptor for a norovirus and identified intestinal tuft cells as the physiologic target cell for mouse norovirus infection. Current work in the Wilen lab is focused on identifying novel therapeutic targets for SARS-CoV2 and elucidating mechanisms COVID-19 pathogenesis. The Wilen lab utilizes a diverse array of techniques to achieve these goals with SARS-CoV2 in the BSL3 including single-cell RNA sequencing, genome-wide CRISPR screening, organoid culture, and transgenic mouse models.
https://wilenlab.com
Education & Training
- InstructorWashington University School of Medicine (2018)
- Resident in Clinical PathologyBarnes-Jewish Hospital (2016)
- MDUniversity of Pennsylvania, Perelman School of Medicine (2013)
- PhDUniversity of Pennsylvania, Perelman School of Medicine (2011)
- ABWashington University in St. Louis, Biology and Economics (2006)
Honors & Recognition
Award | Awarding Organization | Date |
---|---|---|
Odyssey Award | Smith Family Foundation | 2022 |
Young Physician-Scientist Award | American Society for Clinical Investigation | 2021 |
Robert E. Leet and Clara Guthrie Patterson Trust Mentored Research Award | 2020 | |
Paul E. Strandjord Young Investigator Award with Distinction | Academy of Clinical Laboratory Physicians and Scientists | 2017 |
Career Award for Medical Scientists | Burroughs Wellcome Fund | 2017 |
Award for Academic Excellence and Achievement in Pathology | American Society for Clinical Pathology | 2012 |
Departments & Organizations
- Center for Infection and Immunity
- Center for RNA Science and Medicine
- Clinical Chemistry Laboratory
- Genomics, Genetics, and Epigenetics
- Human and Translational Immunology Program
- Immune Monitoring Core Facility
- Immunobiology
- Immunology
- Laboratory Medicine
- Microbiology
- Virology Laboratories
- Yale Cancer Center
- Yale Combined Program in the Biological and Biomedical Sciences (BBS)
- Yale Medicine