David G. Schatz, PhD

Waldemar Von Zedtwitz Professor of Immunobiology and Professor of Molecular Biophysics and Biochemistry; Chair of Immunobiology

Departments & Organizations

Immunobiology: Human and Translational Immunology Program

Diabetes Research Center

Discovery to Cure Internship

Rheumatic Diseases Research Core

Yale Cancer Center: Cancer Immunology

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Biochemistry, Quantitative Biology, Biophysics and Structural Biology (BQBS) | Immunology

Office of Cooperative Research


Dr. Schatz has made fundamental contributions to our understanding of the mechanisms that assemble and diversify antigen receptor genes that encode antibodies and T cell receptors.  He is best known for the discovery of RAG1 and RAG2, subsequent biochemical insights into RAG function and evolutionary origins, and the discovery of two distinct levels of regulation of somatic hypermutation.

Schatz has co-authored over 160 articles, many in prestigious journals, and has been the recipient of numerous prizes and awards, including the Rhodes Scholarship, the Snow Prize (Yale University's top award to a graduating senior), the National Science Foundation Presidential Faculty Fellows Award, the American Association of Immunologists-BD Biosciences Investigator Award, and election to the National Academy of Sciences. He has been active as an editor and reviewer, serving as Co-Editor of the journal Immunity, as a member of the editorial board of a number of journals, and as a member and Chair of the NIH study section Cellular and Molecular Immunology-A.  Schatz has also been very interested in graduate education, serving for many years as the Director of Graduate Studies and Graduate Admissions for Immunobiology and as a member of the Executive Committee of the Biological and Biomedical Sciences (BBS) Program.  He remains strongly committed to enhancing predoctoral and postdoctoral training programs in his current role as Chair of the Department of Immunobiology.

Schatz received B.S. and M.S. degrees in Molecular Biophysics and Biochemistry from Yale University in 1980, and a M.A. degree in Philosophy and Politics from Oxford University in 1982. His Ph.D. degree (1990) and postdoctoral training were done with Dr. David Baltimore at the Massachusetts Institute of Technology and the Whitehead Institute for Biomedical Research.

Education & Training

PhD Massachusetts Institute of Technology (1990)
BA Oxford University, Philosophy and Politics (1982)
BS Yale University, Molecular Biophysics and Biochemistry (1980)
Postdoctoral Fellow Whitehead Institute and MIT

Honors & Recognition

  • Elected to the National Academy of Sciences (2018)

  • Fellow, American Association for the Advancement of Science (2016)

  • Member, American Academy of Arts and Sciences (2014)

  • MERIT Award, NIAID, NIHNational Institutes of Health (2007)

  • AAI-BD Biosciences Investigator AwardAmerican Association of Immunology (2004)

  • National Science Foundation Presidential Faculty Fellows AwardNational Science Foundation (1994)

  • Rhodes Scholarship (1980)

  • Snow Prize, Yale University's top overall award to a graduating studentYale University (1980)

Professional Service

  • MD-PhD Faculty Committee (2009 - 2012)

  • Chair, NIH Study Section CMI-A (2008 - 2010)

  • Biological Sciences Advisory Committee (2004 - 2007)

  • Tenure Advisory Committee for the Biological Sciences (2004 - 2007)

  • Regular member, NIH Study Section CMI-A (2004 - 2006)

  • Editorial Board, Immunological Reviews (2003 - 2008)

  • Editorial Board, Immunity (2003 - Present)

  • Principal Investigator, NIH T32 Training Grant "Yale Interdisciplinary Immunology Training Program" (2003 - Present)

  • Co-Editor, Immunity (2000 - 2003) Co-Editor, Immunity

  • Medical School Tenure Slot Committee (1999 - 2001)

  • BBS Executive Committee (1998 - 2008)

  • Editorial Board, Molecular and Cellular Biology (1996 - Present)

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Contact Info

David G. Schatz, PhD
Lab Location
The Anlyan Center
300 Cedar Street, Ste S 620

New Haven, CT 06519
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Mailing Address
ImmunobiologyPO Box 208011
300 Cedar Street

New Haven, CT 06520-8011

Curriculum Vitae