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Thomas Carpenter, MD

Professor of Pediatrics (Endocrinology) and of Orthopaedics and Rehabilitation and Clinical Professor of Nursing; Director, Yale Center for X-Linked Hypophosphatemia; Medical Director, Hospital Research Unit

Research Summary

Dr. Thomas Carpenter investigates disorders of mineral metabolism in children, including calcium, phosphorus, and Vitamin D (nutritional rickets). Dr. Carpenter is director of the Yale Center for X-Linked Hypophosphatemia (YC-XLH). He also co-chairs a committee which functions in concert with the Human Investigation Committee and the Yale Center for Clinical Investigation to insure the highest quality approach to clinical research and optimum measures of safety in pediatric research.

Specialized Terms: Regulation of phosphate homeostasis and Vitamin D metabolism; Vitamin and mineral nutrition; Bone cell biology; Assessment of bone density in children; Ethical issues in pediatric research

Extensive Research Description

  • Novel therapy of X-linked hypophosphatemia
  • Pathophysiology of X-linked hypophosphatemia
  • Vitamin D response to supplementation in infants and children


Research Interests

Endocrinology; Hypophosphatemia, Familial; Musculoskeletal Diseases; Orthopedics; Pediatrics; Vitamin D; Bone Density

Selected Publications

Clinical Trials

ConditionsStudy Title
Diseases of the Musculoskeletal SystemTumor-induced Osteomalacia Disease Monitoring Program
Diseases of the Musculoskeletal SystemStudy to Assess the Efficacy and Safety of Setrusumab in Participants With Osteogenesis Imperfecta
Diseases of the Kidney & Urinary TractThe Impact of Phosphate Metabolism on Healthy Aging