George Lister, MD
Jean McLean Wallace Professor of Pediatrics and Professor of Cellular And Molecular Physiology
Research & Publications
Biography
News
Research Summary
Dr. Lister works primarily in two areas of research:
- The understanding of oxygen utilization during hypoxia, anemia, and low cardiac output states and the application of the physiologic principles to the care of critically ill infants and children; and
- The utility of physiologic home monitoring to detect infants at risk for SIDS.
He also has had leadership in the creation of the new subspecialty of pediatric critical care medicine, in the reorganization of medical education for pediatric residents and subspecialty fellows, and the development of a medical school curriculum.
Extensive Research Description
- Study of factors affecting risk of infants for SIDS
- Study of factors improving student and resident medical education
Coauthors
Research Interests
Anemia; Cardiac Output, Low; Hypoxia, Brain; Critical Care; Education, Medical; Pediatrics; Physiology; Sudden Infant Death
Selected Publications
- Education and Certification of Fellows: The Tyranny of TimeLister G, Norwood V. Education and Certification of Fellows: The Tyranny of Time. Pediatrics 2014, 133: s82-s84. DOI: 10.1542/peds.2013-3861j.
- HELIOX zur unterstützenden Therapie akuter AsthmaanfälleTrübel H, Apkon M, Lister G. HELIOX zur unterstützenden Therapie akuter Asthmaanfälle. Pneumologie 2007, 61 DOI: 10.1055/s-2007-973221.
- Helium / O2–Gemische (HELIOX) zur Therapie akuter AsthmaanfälleTrübel H, Lister G, Apkon M. Helium / O2–Gemische (HELIOX) zur Therapie akuter Asthmaanfälle. Zeitschrift Für Geburtshilfe Und Neonatologie 2005, 209 DOI: 10.1055/s-2005-871392.
- Mentorship: lessons I wish I learned the first time.Lister G. Mentorship: lessons I wish I learned the first time. Current Opinion In Pediatrics 2004, 16: 579-84. PMID: 15367854, DOI: 10.1097/01.mop.0000139299.13152.e1.
- Chapter 63 Cardiovascular Function During Development and the Response to HypoxiaAnderson P, Kleinman C, Lister G, Talner N. Chapter 63 Cardiovascular Function During Development and the Response to Hypoxia. 2004, 635-669. DOI: 10.1016/b978-0-7216-9654-6.50066-7.
- The importance of the peripheral circulation in critical illnessesPeters J, Mack G, Lister G. The importance of the peripheral circulation in critical illnesses. Intensive Care Medicine 2001, 27: 1446-1458. PMID: 11685337, DOI: 10.1007/s001340101034.
- Cardiorespiratory Events Recorded on Home Monitors: Comparison of Healthy Infants With Those at Increased Risk for SIDSRamanathan R, Corwin M, Hunt C, Lister G, Tinsley L, Baird T, Silvestri J, Crowell D, Hufford D, Martin R, Neuman M, Weese-Mayer D, Cupples L, Peucker M, Willinger M, Keens T, Group F. Cardiorespiratory Events Recorded on Home Monitors: Comparison of Healthy Infants With Those at Increased Risk for SIDS. JAMA 2001, 285: 2199-2207. PMID: 11325321, DOI: 10.1001/jama.285.17.2199.
- Comparison of Apnea Identified by Respiratory Inductance Plethysmography with That Detected by End-tidal CO2 or ThermistorWEESE-MAYER D, CORWIN M, PEUCKER M, DI FIORE J, HUFFORD D, TINSLEY L, NEUMAN M, MARTIN R, BROOKS L, WARD S, LISTER G, WILLINGER M, Group T. Comparison of Apnea Identified by Respiratory Inductance Plethysmography with That Detected by End-tidal CO2 or Thermistor. American Journal Of Respiratory And Critical Care Medicine 2000, 162: 471-480. PMID: 10934073, DOI: 10.1164/ajrccm.162.2.9904029.
- Longitudinal assessment of hemoglobin oxygen saturation in healthy infants during the first 6 months of ageHunt C, Corwin M, Lister G, Weese-Mayer D, Neuman M, Tinsley L, Baird T, Keens T, Cabral H, Group C. Longitudinal assessment of hemoglobin oxygen saturation in healthy infants during the first 6 months of age. The Journal Of Pediatrics 1999, 135: 580-586. PMID: 10547246, DOI: 10.1016/s0022-3476(99)70056-9.
- Cardiovascular Abnormalities in Bronchopulmonary DysplasiaApkon M, Nehgme R, Lister G. Cardiovascular Abnormalities in Bronchopulmonary Dysplasia. 1999, 321-356. DOI: 10.1201/b14831-16.
- Mechanisms of Myocardial Ischemia in Children Receiving β-Agonist Therapy for AsthmaSudikoff S, Banasiak K, Nehgme R, Lister G. Mechanisms of Myocardial Ischemia in Children Receiving β-Agonist Therapy for Asthma. Pediatric Research 1999, 45: 46-46. DOI: 10.1203/00006450-199904020-00277.
- Agreement among Raters in Assessment of Physiologic Waveforms Recorded by a Cardiorespiratory Monitor for Home UseCorwin M, Lister G, Silvestri J, Peucker M, Brooks L, Davidson Ward S, Hunt C, Neuman M, Crowell D, Colton T. Agreement among Raters in Assessment of Physiologic Waveforms Recorded by a Cardiorespiratory Monitor for Home Use. Pediatric Research 1998, 44: 682-690. PMID: 9803449, DOI: 10.1203/00006450-199811000-00010.
- Ability to Predict a Family's Use of a Home Respiratory Inductance Plethysmography (RIP) Monitor † 687Silverstri J, Corwin M, Smok-Pearsall S, Zhang A, Baird T, Kapuniai L, Hunt C, Crowell D, Palmer P, Mendenhall R, Lister G, Willinger M, Hoppenbrouwers T. Ability to Predict a Family's Use of a Home Respiratory Inductance Plethysmography (RIP) Monitor † 687. Pediatric Research 1998, 43: 119-119. DOI: 10.1203/00006450-199804001-00708.
- Effects of rate and amplitude of breathing on respiratory system elastance and resistance during growth of healthy childrenGalal M, Habib R, Jaeger D, Lister G. Effects of rate and amplitude of breathing on respiratory system elastance and resistance during growth of healthy children. Pediatric Pulmonology 1998, 25: 270-277. PMID: 9590487, DOI: 10.1002/(sici)1099-0496(199804)25:4<270::aid-ppul7>3.0.co;2-o.
- Infant Polysomnography: ReliabilityCrowell D, Brooks L, Colton T, Corwin M, Hoppenbrouwers T, Hunt C, Kapuniai L, Lister G, Neuman M, Peucker M, Ward S, Weese-Mayer D, Willinger M, Committee T. Infant Polysomnography: Reliability. Sleep 1997, 20: 553-560. PMID: 9322271, DOI: 10.1093/sleep/20.7.553.
- Venous and arterial reflex responses to positive-pressure breathing and lower body negative pressurePeters J, Lister G, Nadel E, Mack G. Venous and arterial reflex responses to positive-pressure breathing and lower body negative pressure. Journal Of Applied Physiology 1997, 82: 1889-1896. PMID: 9173955, DOI: 10.1152/jappl.1997.82.6.1889.
- Hepatic and Gastrointestinal Oxygen and Lactate Metabolism during Low Cardiac Output in LambsFahey J, Lister G, Sanfilippo D, Edelstone D. Hepatic and Gastrointestinal Oxygen and Lactate Metabolism during Low Cardiac Output in Lambs. Pediatric Research 1997, 41: 842-851. PMID: 9167197, DOI: 10.1203/00006450-199706000-00008.
- Apnea duration: Respiratory Inductance Plethysmography (RIP) and Transthoracic Impedance (TTI) Pneumography vs. Polysomnography (PSG) † 1791Corwin M, Weese-Mayer D, Neuman M, Crowell D, Ward S, Brooks L, Hunt C, Lister G, Willinger M. Apnea duration: Respiratory Inductance Plethysmography (RIP) and Transthoracic Impedance (TTI) Pneumography vs. Polysomnography (PSG) † 1791. Pediatric Research 1997, 41: 301-301. DOI: 10.1203/00006450-199704001-01810.
- Inter-rater Agreement in Scoring Home Cardiorespiratory Tracings • 1790Corwin M, Lister G, Silvestri J, Peucker M, Brooks L, Ward S, Hunt C, Neuman M, Crowell D, Colton T. Inter-rater Agreement in Scoring Home Cardiorespiratory Tracings • 1790. Pediatric Research 1997, 41: 301-301. DOI: 10.1203/00006450-199704001-01809.
- Longitudinal Assessment of Oxygen Saturation and Sleep Position in Healthy Term Infants During the First 6 Months of Life † 1180Hunt C, Corwin M, Peucker M, Weese-Mayer D, Tinsley L, Keens T, Lister G, Neuman M, Baird T. Longitudinal Assessment of Oxygen Saturation and Sleep Position in Healthy Term Infants During the First 6 Months of Life † 1180. Pediatric Research 1997, 41: 199-199. DOI: 10.1203/00006450-199704001-01199.
- Assessment of Sleep Position Over Time Among Infants At Risk of Sudden Infant Death Syndrom (SIDS) and Healthy Term Infants. † 462Silvestri J, Mulvey K, Tinsley L, Keens T, Hunt C, Baird T, Lister G. Assessment of Sleep Position Over Time Among Infants At Risk of Sudden Infant Death Syndrom (SIDS) and Healthy Term Infants. † 462. Pediatric Research 1997, 41: 79-79. DOI: 10.1203/00006450-199704001-00482.
- EFFECTS OF SUBJECT SIZE AND BREATHING PATTERN ON RESPIRATORY MECHANICS.† 2298Galal M, Habib R, Lister G. EFFECTS OF SUBJECT SIZE AND BREATHING PATTERN ON RESPIRATORY MECHANICS.† 2298. Pediatric Research 1996, 39: 386-386. DOI: 10.1203/00006450-199604001-02323.
- SUCCESSFUL USE OF A HOME RESPIRATORY INDUCTANCE PLETHYSMOGRAPHY (RIP) MONITOR IN INFANTS AT-RISK OF SUDDEN INFANT DEATH SYNDROME (SIDS). † 829Silvestri J, Crowell D, Peucker M, Ramanathan R, Hunt C, Brooks L, Lister G. SUCCESSFUL USE OF A HOME RESPIRATORY INDUCTANCE PLETHYSMOGRAPHY (RIP) MONITOR IN INFANTS AT-RISK OF SUDDEN INFANT DEATH SYNDROME (SIDS). † 829. Pediatric Research 1996, 39: 141-141. DOI: 10.1203/00006450-199604001-00851.
- ASSESSMENT OF SLEEP POSITION AMONG INFANTS AT RISK OF SUDDEN INFANT DEATH SYNDROME (SIDS). † 661Silvestri J, Corwin M, Tinsley L, Keens T, Hunt C, Baird T, Lister G. ASSESSMENT OF SLEEP POSITION AMONG INFANTS AT RISK OF SUDDEN INFANT DEATH SYNDROME (SIDS). † 661. Pediatric Research 1996, 39: 113-113. DOI: 10.1203/00006450-199604001-00683.
- VENOUS AND ARTERIAL REFLEX RESPONSES TO POSITIVE PRESSURE BREATHING AND SIMULATED HEMORRHAGE. † 301Peters J, Mack G, Nadel E, Lister G. VENOUS AND ARTERIAL REFLEX RESPONSES TO POSITIVE PRESSURE BREATHING AND SIMULATED HEMORRHAGE. † 301. Pediatric Research 1996, 39: 53-53. DOI: 10.1203/00006450-199604001-00321.
- Metabolic responses to hypoxiaLISTER G. Metabolic responses to hypoxia. Critical Care Medicine 1993, 21: s340. PMID: 8395993, DOI: 10.1097/00003246-199309001-00022.
- Oxygen transport during anemic hypoxia in pigs: effects of digoxin on metabolismSaltiel A, Sanfilippo DJ, Hendler R, Lister G. Oxygen transport during anemic hypoxia in pigs: effects of digoxin on metabolism. American Journal Of Physiology 1992, 263: h208-h217. PMID: 1636760, DOI: 10.1152/ajpheart.1992.263.1.h208.
- New approaches to diagnosis and therapy in pediatric critical careBogue C, Lister G. New approaches to diagnosis and therapy in pediatric critical care. Current Opinion In Pediatrics 1992, 4: 431-436. DOI: 10.1097/00008480-199206000-00007.
- Functional assessment of pulmonary capillary surface area in the 2-mo-old lambPitt B, Lister G, Fontan J, Davies P. Functional assessment of pulmonary capillary surface area in the 2-mo-old lamb. Journal Of Applied Physiology 1991, 70: 1677-1685. PMID: 1711522, DOI: 10.1152/jappl.1991.70.4.1677.
- Response to Low Cardiac Output: Developmental Differences in Metabolism during Oxygen Deficit and Recovery in LambsFahey J, Lister G. Response to Low Cardiac Output: Developmental Differences in Metabolism during Oxygen Deficit and Recovery in Lambs. Pediatric Research 1989, 26: 180-187. PMID: 2587117, DOI: 10.1203/00006450-198909000-00003.
- Perioperative Care of the Infant with Congenital Heart DiseaseTalner N, Lister G. Perioperative Care of the Infant with Congenital Heart Disease. Cardiology Clinics 1989, 7: 419-438. PMID: 2659183, DOI: 10.1016/s0733-8651(18)30446-6.
- Interpretation of Metabolic Function of the Lung Influence of Perfusion, Kinetics, and InjuryPitt B, Lister G. Interpretation of Metabolic Function of the Lung Influence of Perfusion, Kinetics, and Injury. Clinics In Chest Medicine 1989, 10: 1-12. PMID: 2650960, DOI: 10.1016/s0272-5231(21)00599-2.
- Resuscitation of cold water immersion victims with cardiopulmonary bypassSaltiel A, Kopf G, Elefteriades J, Hammond G, Shaffer W, Farrell D, Ponn R, Lister G. Resuscitation of cold water immersion victims with cardiopulmonary bypass. Journal Of Critical Care 1989, 4: 54-57. DOI: 10.1016/0883-9441(89)90092-0.
- Effect of hemoglobin concentration on critical cardiac output and oxygen transportHeusser F, Fahey JT, Lister G. Effect of hemoglobin concentration on critical cardiac output and oxygen transport. American Journal Of Physiology 1989, 256: h527-h532. PMID: 2916686, DOI: 10.1152/ajpheart.1989.256.2.h527.
- Hypoxanthine and lactate concentrations in lambs during hypoxic and stagnant hypoxiaMoss M, Kurzner S, Razlog Y, Lister G. Hypoxanthine and lactate concentrations in lambs during hypoxic and stagnant hypoxia. American Journal Of Physiology 1988, 255: h53-h59. PMID: 3394825, DOI: 10.1152/ajpheart.1988.255.1.h53.
- Postnatal growth of the sheep lung: A morphometric studyDavies P, Reid L, Lister G, Pitt B. Postnatal growth of the sheep lung: A morphometric study. The Anatomical Record 1988, 220: 281-286. PMID: 3364753, DOI: 10.1002/ar.1092200308.
- Measurements of Blood FlowBerman W, Lister G, Pitt B, Hoffman J. Measurements of Blood Flow. Advances In Pediatrics 1988, 35: 427-452. PMID: 3055865, DOI: 10.1016/s0065-3101(24)00184-1.
- Oxygen transport in low cardiac output statesFahey J, Lister G. Oxygen transport in low cardiac output states. Journal Of Critical Care 1987, 2: 288-305. DOI: 10.1016/0883-9441(87)90072-4.
- Oxygen Transport and Metabolism in the Conscious Lamb: The Effects of HypoxemiaMoss M, Moreau G, Lister G. Oxygen Transport and Metabolism in the Conscious Lamb: The Effects of Hypoxemia. Pediatric Research 1987, 22: 177-183. PMID: 3658543, DOI: 10.1203/00006450-198708000-00016.
- Postnatal changes in critical cardiac output and oxygen transport in conscious lambsFahey J, Lister G. Postnatal changes in critical cardiac output and oxygen transport in conscious lambs. American Journal Of Physiology 1987, 253: h100-h106. PMID: 3605355, DOI: 10.1152/ajpheart.1987.253.1.h100.
- Correlation of pulmonary ACE activity and capillary surface area during postnatal developmentPitt B, Lister G, Davies P, Reid L. Correlation of pulmonary ACE activity and capillary surface area during postnatal development. Journal Of Applied Physiology 1987, 62: 2031-2041. PMID: 3036759, DOI: 10.1152/jappl.1987.62.5.2031.
- Effects of changes in pulmonary perfusion and surface area on endothelial ace activityPitt B, Lister G, Davies P, Reid L. Effects of changes in pulmonary perfusion and surface area on endothelial ace activity. Annals Of Biomedical Engineering 1987, 15: 229-238. PMID: 3035966, DOI: 10.1007/bf02364057.
- Adverse Occurrences in the Pediatric Intensive Care UnitRiggs C, Lister G. Adverse Occurrences in the Pediatric Intensive Care Unit. Pediatric Clinics Of North America 1987, 34: 93-117. PMID: 3543829, DOI: 10.1016/s0031-3955(16)36183-1.
- Effect of hypoxia and hypercapnia on ACE activity in the cerebral microcirculation of anesthetized dogsPitt B, Lister G, Dawson C, Linehan J. Effect of hypoxia and hypercapnia on ACE activity in the cerebral microcirculation of anesthetized dogs. American Journal Of Physiology 1986, 250: h806-h814. PMID: 3010743, DOI: 10.1152/ajpheart.1986.250.5.h806.
- Repair of Aortic Coarctation in the First Three Months of Life: Immediate and Long-Term ResultsKopf G, Hellenbrand W, Kleinman C, Lister G, Talner N, Laks H. Repair of Aortic Coarctation in the First Three Months of Life: Immediate and Long-Term Results. The Annals Of Thoracic Surgery 1986, 41: 425-430. PMID: 3963920, DOI: 10.1016/s0003-4975(10)62701-4.
- A simple method for reducing cardiac output in the conscious lambFahey J, Lister G. A simple method for reducing cardiac output in the conscious lamb. American Journal Of Physiology 1985, 249: h188-h192. PMID: 4014483, DOI: 10.1152/ajpheart.1985.249.1.h188.
- Kinetics of pulmonary angiotensin-converting enzyme activity in conscious developing lambsPitt B, Lister G. Kinetics of pulmonary angiotensin-converting enzyme activity in conscious developing lambs. Journal Of Applied Physiology 1984, 57: 1158-1166. PMID: 6094403, DOI: 10.1152/jappl.1984.57.4.1158.
- Depressed Pulmonary Metabolic Function After Experimental MicroembolizationPitt B, Flink J, Lister G, Gillis C. Depressed Pulmonary Metabolic Function After Experimental Microembolization. Anesthesiology 1984, 61: a500. DOI: 10.1097/00000542-198409001-00500.
- Effects of alterations of oxygen transport on the neonate.Lister G, Moreau G, Moss M, Talner N. Effects of alterations of oxygen transport on the neonate. Seminars In Perinatology 1984, 8: 192-204. PMID: 6204388.
- Epiglottitis—Duration of Intubation and FeverROTHSTEIN P, LISTER G, Smith R. Epiglottitis—Duration of Intubation and Fever. Survey Of Anesthesiology 1984, 28: 245. DOI: 10.1097/00132586-198406000-00093.
- Functional assessment of the pulmonary microcirculation during postnatal development.Lister G, Kopf G, Pitt B. Functional assessment of the pulmonary microcirculation during postnatal development. Neonatology 1984, 4: 85-99. PMID: 6091021.
- Pulmonary metabolic function in the awake lamb: effect of development and hypoxiaPitt B, Lister G. Pulmonary metabolic function in the awake lamb: effect of development and hypoxia. Journal Of Applied Physiology 1983, 55: 383-391. PMID: 6618931, DOI: 10.1152/jappl.1983.55.2.383.
- Cardiopulmonary Interactions in the Infant with Congenital Cardiac DiseaseLister G, Pitt B. Cardiopulmonary Interactions in the Infant with Congenital Cardiac Disease. Clinics In Chest Medicine 1983, 4: 219-232. PMID: 6342921, DOI: 10.1016/s0272-5231(21)00200-8.
- EVIDENCE OF BRONCHIAL HYPERREACTIVITY IN INFANTS WITH ACUTE BRONCHIOLITISMotoyama E, Lister G, Mallory G, Mestad P, Rothstein P, Weng T. EVIDENCE OF BRONCHIAL HYPERREACTIVITY IN INFANTS WITH ACUTE BRONCHIOLITIS. Anesthesiology 1982, 57: a100. DOI: 10.1097/00000542-198209001-00100.
- Physiologic Effects of Increasing Hemoglobin Concentration in Left-to-Right Shunting in Infants with Ventricular Septal DefectsLister G, Hellenbrand W, Kleinman C, Talner N. Physiologic Effects of Increasing Hemoglobin Concentration in Left-to-Right Shunting in Infants with Ventricular Septal Defects. New England Journal Of Medicine 1982, 306: 502-506. PMID: 7057857, DOI: 10.1056/nejm198203043060902.
- Effect of physical training on exercise performance of children following surgical repair of congenital heart disease.Goldberg B, Fripp R, Lister G, Loke J, Nicholas J, Talner N. Effect of physical training on exercise performance of children following surgical repair of congenital heart disease. Pediatrics 1981, 68: 691-9. PMID: 7312473, DOI: 10.1542/peds.68.5.691.
- 150 EFFECTS OF EXCHANGE TRANSFUSION(ExTx) ON THE PULMONARY AND SYSTEMIC CIRCULATIONS IN LEFT-TO-RIGHT SHUNTS(QLR)Hellenbrand W, Lister G, Kleinman C, Talner N. 150 EFFECTS OF EXCHANGE TRANSFUSION(ExTx) ON THE PULMONARY AND SYSTEMIC CIRCULATIONS IN LEFT-TO-RIGHT SHUNTS(QLR). Pediatric Research 1981, 15: 464-464. DOI: 10.1203/00006450-198104001-00159.
- The Pathophysiology of disorders of oxygen transport in the infantTalner N, Lister G. The Pathophysiology of disorders of oxygen transport in the infant. Current Problems In Pediatric And Adolescent Health Care 1981, 11: 7-50. PMID: 7226876, DOI: 10.1016/0045-9380(81)90037-2.
- Repair of Complex Congenital Cardiac Defects with the Valved ConduitLaks H, Hellenbrand W, Stansel H, Kleinman C, Lister G, Talner N. Repair of Complex Congenital Cardiac Defects with the Valved Conduit. Surgical Clinics Of North America 1980, 60: 1225-1237. PMID: 7434163, DOI: 10.1016/s0039-6109(16)42246-2.
- Repair of complex congenital cardiac defects with the valved conduit.Laks H, Hellenbrand W, Stansel H, Kleinman C, Lister G, Talner N. Repair of complex congenital cardiac defects with the valved conduit. Connecticut Medicine 1980, 44: 362-5. PMID: 7398299.