Angus Nairn, PhD

• Amy Arnsten
• Carolyn Fredericks
• Christopher van Dyck
• Deepak Cyril Dsouza
• Flora Vaccarino
• Fred Sanford Gorelick
• Hongyu Zhao
• Jane Rebecca Taylor
• Leonard Kaczmarek
• Marina Picciotto
• TuKiet Lam
• Vincent Pieribone

Dopamine; Huntington Disease; Parkinson Disease; Protein Kinases; Psychiatry; Schizophrenia; Signal Transduction

• Chronic GCPII (glutamate‐carboxypeptidase‐II) inhibition reduces pT217Tau levels in the entorhinal and dorsolateral prefrontal cortices of aged macaquesBathla S, Datta D, Liang F, Barthelemy N, Wiseman R, Slusher B, Asher J, Zeiss C, Ekanayake‐Alper D, Holden D, Terwilliger G, Duque A, Arellano J, van Dyck C, Bateman R, Xie Z, Nairn A, Arnsten A. Chronic GCPII (glutamate‐carboxypeptidase‐II) inhibition reduces pT217Tau levels in the entorhinal and dorsolateral prefrontal cortices of aged macaques. Alzheimer's & Dementia: Translational Research & Clinical Interventions 2023, 9: e12431. PMID: 37915375, PMCID: PMC10617575, DOI: 10.1002/trc2.12431.
• Operant training for highly palatable food alters translating mRNA in nucleus accumbens D2 neurons and reveals a modulatory role of NeurochondrinMontalban E, Giralt A, Taing L, Nakamura Y, Pelosi A, Brown M, de Pins B, Valjent E, Martin M, Nairn A, Greengard P, Flajolet M, Hervé D, Gambardella N, Roussarie J, Girault J. Operant training for highly palatable food alters translating mRNA in nucleus accumbens D2 neurons and reveals a modulatory role of Neurochondrin. Biological Psychiatry 2023 PMID: 37579933, DOI: 10.1016/j.biopsych.2023.08.006.
• Differential Effects of Cocaine and Morphine on the Diurnal Regulation of the Mouse Nucleus Accumbens ProteomeKetchesin K, Becker-Krail D, Xue X, Wilson R, Lam T, Williams K, Nairn A, Tseng G, Logan R. Differential Effects of Cocaine and Morphine on the Diurnal Regulation of the Mouse Nucleus Accumbens Proteome. Journal Of Proteome Research 2023, 22: 2377-2390. PMID: 37311105, PMCID: PMC10392613, DOI: 10.1021/acs.jproteome.3c00126.
• Adult-specific Reelin expression alters striatal neuronal organization: implications for neuropsychiatric disordersPardo M, Gregorio S, Montalban E, Pujadas L, Elias-Tersa A, Masachs N, Vílchez-Acosta A, Parent A, Auladell C, Girault J, Vila M, Nairn A, Manso Y, Soriano E. Adult-specific Reelin expression alters striatal neuronal organization: implications for neuropsychiatric disorders. Frontiers In Cellular Neuroscience 2023, 17: 1143319. PMID: 37153634, PMCID: PMC10157100, DOI: 10.3389/fncel.2023.1143319.
• Peripheral signature of altered synaptic integrity in young onset cannabis use disorder: A proteomic study of circulating extracellular vesiclesGanesh S, Lam T, Garcia-Milian R, D'Souza D, Nairn A, Elgert K, Eitan E, Ranganathan M. Peripheral signature of altered synaptic integrity in young onset cannabis use disorder: A proteomic study of circulating extracellular vesicles. The World Journal Of Biological Psychiatry 2023, 24: 603-613. PMID: 36994633, PMCID: PMC10471733, DOI: 10.1080/15622975.2023.2197039.
• Uncovering biology by single-cell proteomicsMansuri M, Williams K, Nairn A. Uncovering biology by single-cell proteomics. Communications Biology 2023, 6: 381. PMID: 37031277, PMCID: PMC10082756, DOI: 10.1038/s42003-023-04635-2.
• Diagnostic and Prognostic Performance of the Modified Lumipulse pTau 181 Assay in Plasma for Alzheimer’s DiseaseWilson E, Young C, Benitez J, Vandijck M, Swarovski M, Shahid M, Corso N, Kennedy G, Trelle A, Channappa D, Belnap M, Lind B, Le Bastard N, Quinn J, Nairn A, Kerchner G, Sha S, Wagner A, Henderson V, Longo F, Wyss‐Coray T, Poston K, Mormino E, Andreasson K. Diagnostic and Prognostic Performance of the Modified Lumipulse pTau 181 Assay in Plasma for Alzheimer’s Disease. Alzheimer's & Dementia 2022, 18 DOI: 10.1002/alz.060879.
• Applying Data‐Independent Acquisition Mass Spectrometry on Cerebrospinal Fluid Samples from a Neurology Clinic for Biomarker Discovery in Alzheimer’s Diseasede Geus M, Leslie S, Ramirez C, Trombetta B, Wang W, Lam T, Gotti C, Roux‐Dalvai F, Droit A, Nairn A, Arnold S, Carlyle B. Applying Data‐Independent Acquisition Mass Spectrometry on Cerebrospinal Fluid Samples from a Neurology Clinic for Biomarker Discovery in Alzheimer’s Disease. Alzheimer's & Dementia 2022, 18 DOI: 10.1002/alz.064314.
• Performance of a fully-automated Lumipulse plasma phospho-tau181 assay for Alzheimer’s diseaseWilson E, Young C, Ramos Benitez J, Swarovski M, Feinstein I, Vandijck M, Le Guen Y, Kasireddy N, Shahid M, Corso N, Wang Q, Kennedy G, Trelle A, Lind B, Channappa D, Belnap M, Ramirez V, Skylar-Scott I, Younes K, Yutsis M, Le Bastard N, Quinn J, van Dyck C, Nairn A, Fredericks C, Tian L, Kerchner G, Montine T, Sha S, Davidzon G, Henderson V, Longo F, Greicius M, Wagner A, Wyss-Coray T, Poston K, Mormino E, Andreasson K. Performance of a fully-automated Lumipulse plasma phospho-tau181 assay for Alzheimer’s disease. Alzheimer's Research & Therapy 2022, 14: 172. PMID: 36371232, PMCID: PMC9652927, DOI: 10.1186/s13195-022-01116-2.
• DARPP-32/protein phosphatase 1 regulates Rasgrp2 as a novel component of dopamine D1 receptor signaling in striatumKuroiwa M, Shuto T, Nagai T, Amano M, Kaibuchi K, Nairn A, Nishi A. DARPP-32/protein phosphatase 1 regulates Rasgrp2 as a novel component of dopamine D1 receptor signaling in striatum. Neurochemistry International 2022, 162: 105438. PMID: 36351540, DOI: 10.1016/j.neuint.2022.105438.
• T124. PERIPHERAL SIGNATURE OF ALTERED SYNAPTIC INTEGRITY IN YOUNG ONSET CANNABIS USE DISORDER: AN EXPLORATORY PROTEOMIC STUDY OF CIRCULATING EXTRACELLULAR VESICLESGanesh S, Lam T, Nairn A, Milian R, Eitan E, Ranganathan M. T124. PERIPHERAL SIGNATURE OF ALTERED SYNAPTIC INTEGRITY IN YOUNG ONSET CANNABIS USE DISORDER: AN EXPLORATORY PROTEOMIC STUDY OF CIRCULATING EXTRACELLULAR VESICLES. European Neuropsychopharmacology 2022, 63: e235-e236. DOI: 10.1016/j.euroneuro.2022.07.420.
• Myosin light chain phosphatase catalytic subunit dephosphorylates cardiac myosin via mechanisms dependent and independent of the MYPT regulatory subunitsLee E, Liu Z, Nguyen N, Nairn A, Chang AN. Myosin light chain phosphatase catalytic subunit dephosphorylates cardiac myosin via mechanisms dependent and independent of the MYPT regulatory subunits. Journal Of Biological Chemistry 2022, 298: 102296. PMID: 35872014, PMCID: PMC9418503, DOI: 10.1016/j.jbc.2022.102296.
• PP1cβ dephosphorylates cardiac myosin by MYPT‐dependent and independent mechanismsLee E, Liu Z, Nguyen N, Nairn A, Chang A. PP1cβ dephosphorylates cardiac myosin by MYPT‐dependent and independent mechanisms. The FASEB Journal 2022, 36 DOI: 10.1096/fasebj.2022.36.s1.r3877.
• Loss of Ftsj1 perturbs codon-specific translation efficiency in the brain and is associated with X-linked intellectual disabilityNagayoshi Y, Chujo T, Hirata S, Nakatsuka H, Chen C, Takakura M, Miyauchi K, Ikeuchi Y, Carlyle B, Kitchen R, Suzuki T, Katsuoka F, Yamamoto M, Goto Y, Tanaka M, Natsume K, Nairn A, Suzuki T, Tomizawa K, Wei F. Loss of Ftsj1 perturbs codon-specific translation efficiency in the brain and is associated with X-linked intellectual disability. Science Advances 2021, 7: eabf3072. PMID: 33771871, PMCID: PMC7997516, DOI: 10.1126/sciadv.abf3072.
• Development of a robust and stable mass based spectrometry method for analysis of Alzheimer’s disease biomarkers in human cerebrospinal fluidLeslie S, Wilson R, Trombetta B, Kivisäkk P, Arnold S, Nairn A, Carlyle B. Development of a robust and stable mass based spectrometry method for analysis of Alzheimer’s disease biomarkers in human cerebrospinal fluid. Alzheimer's & Dementia 2020, 16 DOI: 10.1002/alz.042035.
• Identification of NPTX2 as a prognostic biomarker of Alzheimer’s disease through a longitudinal CSF proteomics study in ADNI subjectsLibiger O, Shaw L, Watson M, Nairn A, Umaña K, Canet‐Avilés R, Jack C, Breton Y, Cortes L, Chelsky D, Spellman D, Baker S, Raghavan N, Potter W. Identification of NPTX2 as a prognostic biomarker of Alzheimer’s disease through a longitudinal CSF proteomics study in ADNI subjects. Alzheimer's & Dementia 2020, 16 DOI: 10.1002/alz.047605.
• Biochemical characterization of age‐related calcium‐cAMP‐PKA signaling dysregulation and its effect on tau pathology in rhesus monkey cortexLeslie S, Datta D, Wang M, van Dyck C, Arnsten A, Nairn A. Biochemical characterization of age‐related calcium‐cAMP‐PKA signaling dysregulation and its effect on tau pathology in rhesus monkey cortex. Alzheimer's & Dementia 2020, 16 DOI: 10.1002/alz.042017.
• Proteomic profiling of nucleus accumbens synaptosomes following short- and long-term withdrawal from cocaine self-administration in miceYim Y, Browne C, Wang J, Wilson R, Nairn A, Dong Y, Nestler E. Proteomic profiling of nucleus accumbens synaptosomes following short- and long-term withdrawal from cocaine self-administration in mice. IBRO Neuroscience Reports 2019, 6: s371. DOI: 10.1016/j.ibror.2019.07.1178.
• In Memoriam: David C. Gadsby, PhDAndersen O, Nairn A, Palmer L, Shapley R. In Memoriam: David C. Gadsby, PhD. The Journal Of General Physiology 2019, 151: 967-969. PMCID: PMC6683670, DOI: 10.1085/jgp.201912400.
• P1‐269: DEVELOPMENT AND TECHNICAL VALIDATION OF A DATA‐INDEPENDENT ACQUISITION METHODOLOGY FOR ANALYSIS OF HUMAN ALZHEIMER'S DISEASE CEREBROSPINAL FLUIDLeslie S, Wilson R, Kivisäkk P, Kandigian S, Trombetta B, Nairn A, Arnold S, Carlyle B. P1‐269: DEVELOPMENT AND TECHNICAL VALIDATION OF A DATA‐INDEPENDENT ACQUISITION METHODOLOGY FOR ANALYSIS OF HUMAN ALZHEIMER'S DISEASE CEREBROSPINAL FLUID. Alzheimer's & Dementia 2019, 15: p342-p342. DOI: 10.1016/j.jalz.2019.06.824.
• Development of Targeted Mass Spectrometry-Based Approaches for Quantitation of Proteins Enriched in the Postsynaptic Density (PSD)Wilson RS, Rauniyar N, Sakaue F, Lam TT, Williams KR, Nairn AC. Development of Targeted Mass Spectrometry-Based Approaches for Quantitation of Proteins Enriched in the Postsynaptic Density (PSD). Proteomes 2019, 7: 12. PMID: 30986977, PMCID: PMC6630806, DOI: 10.3390/proteomes7020012.
• Integrative functional genomic analysis of human brain development and neuropsychiatric risksLi M, Santpere G, Imamura Kawasawa Y, Evgrafov OV, Gulden FO, Pochareddy S, Sunkin SM, Li Z, Shin Y, Zhu Y, Sousa AMM, Werling DM, Kitchen RR, Kang HJ, Pletikos M, Choi J, Muchnik S, Xu X, Wang D, Lorente-Galdos B, Liu S, Giusti-Rodríguez P, Won H, de Leeuw C, Pardiñas AF, Hu M, Jin F, Li Y, Owen M, O’Donovan M, Walters J, Posthuma D, Reimers M, Levitt P, Weinberger D, Hyde T, Kleinman J, Geschwind D, Hawrylycz M, State M, Sanders S, Sullivan P, Gerstein M, Lein E, Knowles J, Sestan N, Willsey A, Oldre A, Szafer A, Camarena A, Cherskov A, Charney A, Abyzov A, Kozlenkov A, Safi A, Jones A, Ashley-Koch A, Ebbert A, Price A, Sekijima A, Kefi A, Bernard A, Amiri A, Sboner A, Clark A, Jaffe A, Tebbenkamp A, Sodt A, Guillozet-Bongaarts A, Nairn A, Carey A, Huttner A, Chervenak A, Szekely A, Shieh A, Harmanci A, Lipska B, Carlyle B, Gregor B, Kassim B, Sheppard B, Bichsel C, Hahn C, Lee C, Chen C, Kuan C, Dang C, Lau C, Cuhaciyan C, Armoskus C, Mason C, Liu C, Slaughterbeck C, Bennet C, Pinto D, Polioudakis D, Franjic D, Miller D, Bertagnolli D, Lewis D, Feng D, Sandman D, Clarke D, Williams D, DelValle D, Fitzgerald D, Shen E, Flatow E, Zharovsky E, Burke E, Olson E, Fulfs E, Mattei E, Hadjimichael E, Deelman E, Navarro F, Wu F, Lee F, Cheng F, Goes F, Vaccarino F, Liu F, Hoffman G, Gürsoy G, Gee G, Mehta G, Coppola G, Giase G, Sedmak G, Johnson G, Wray G, Crawford G, Gu G, van Bakel H, Witt H, Yoon H, Pratt H, Zhao H, Glass I, Huey J, Arnold J, Noonan J, Bendl J, Jochim J, Goldy J, Herstein J, Wiseman J, Miller J, Mariani J, Stoll J, Moore J, Szatkiewicz J, Leng J, Zhang J, Parente J, Rozowsky J, Fullard J, Hohmann J, Morris J, Phillips J, Warrell J, Shin J, An J, Belmont J, Nyhus J, Pendergraft J, Bryois J, Roll K, Grennan K, Aiona K, White K, Aldinger K, Smith K, Girdhar K, Brouner K, Mangravite L, Brown L, Collado-Torres L, Cheng L, Gourley L, Song L, Ubieta L, Habegger L, Ng L, Hauberg M, Onorati M, Webster M, Kundakovic M, Skarica M, Reimers M, Johnson M, Chen M, Garrett M, Sarreal M, Reding M, Gu M, Peters M, Fisher M, Gandal M, Purcaro M, Smith M, Brown M, Shibata M, Brown M, Xu M, Yang M, Ray M, Shapovalova N, Francoeur N, Sjoquist N, Mastan N, Kaur N, Parikshak N, Mosqueda N, Ngo N, Dee N, Ivanov N, Devillers O, Roussos P, Parker P, Manser P, Wohnoutka P, Farnham P, Zandi P, Emani P, Dalley R, Mayani R, Tao R, Gittin R, Straub R, Lifton R, Jacobov R, Howard R, Park R, Dai R, Abramowicz S, Akbarian S, Schreiner S, Ma S, Parry S, Shapouri S, Weissman S, Caldejon S, Mane S, Ding S, Scuderi S, Dracheva S, Butler S, Lisgo S, Rhie S, Lindsay S, Datta S, Souaiaia T, Roychowdhury T, Gomez T, Naluai-Cecchini T, Beach T, Goodman T, Gao T, Dolbeare T, Fliss T, Reddy T, Chen T, Hyde T, Brunetti T, Lemon T, Desta T, Borrman T, Haroutunian V, Spitsyna V, Swarup V, Shi X, Jiang Y, Xia Y, Chen Y, Jiang Y, Wang Y, Chae Y, Yang Y, Kim Y, Riley Z, Krsnik Z, Deng Z, Weng Z, Lin Z, Li Z. Integrative functional genomic analysis of human brain development and neuropsychiatric risks. Science 2018, 362 PMID: 30545854, PMCID: PMC6413317, DOI: 10.1126/science.aat7615.
• Transcriptome and epigenome landscape of human cortical development modeled in organoidsAmiri A, Coppola G, Scuderi S, Wu F, Roychowdhury T, Liu F, Pochareddy S, Shin Y, Safi A, Song L, Zhu Y, Sousa AMM, Gerstein M, Crawford G, Sestan N, Abyzov A, Vaccarino F, Akbarian S, An J, Armoskus C, Ashley-Koch A, Beach T, Belmont J, Bendl J, Borrman T, Brown L, Brown M, Brown M, Brunetti T, Bryois J, Burke E, Camarena A, Carlyle B, Chae Y, Charney A, Chen C, Cheng L, Cherskov A, Choi J, Clarke D, Collado-Torres L, Dai R, De La Torre Ubieta L, DelValle D, Devillers O, Dracheva S, Emani P, Evgrafov O, Farnham P, Fitzgerald D, Flatow E, Francoeur N, Fullard J, Gandal M, Gao T, Garrett M, Geschwind D, Giase G, Girdhar K, Giusti-Rodriguez P, Goes F, Goodman T, Grennan K, Gu M, Gürsoy G, Hadjimichael E, Hahn C, Haroutunian V, Hauberg M, Hoffman G, Huey J, Hyde T, Ivanov N, Jacobov R, Jaffe A, Jiang Y, Jiang Y, Johnson G, Kassim B, Kefi A, Kim Y, Kitchen R, Kleiman J, Knowles J, Kozlenkov A, Li M, Li Z, Lipska B, Liu C, Liu S, Mangravite L, Mariani J, Mattei E, Miller D, Moore J, Nairn A, Navarro F, Park R, Peters M, Pinto D, Pochareddy S, Polioudakis D, Pratt H, Price A, Purcaro M, Ray M, Reddy T, Rhie S, Roussos P, Sanders S, Santpere G, Schreiner S, Sheppard B, Shi X, Shieh A, Shin J, Skarica M, Song L, Sousa A, Spitsyna V, State M, Sullivan P, Swarup V, Szatkiewicz J, Szekely A, Tao R, van Bakel H, Wang Y, Wang D, Warrell J, Webster M, Weissman S, Weng Z, Werling D, White K, Willsey J, Wiseman J, Witt H, Won H, Wray G, Xia Y, Xu M, Yang Y, Yang M, Zandi P, Zhang J, Zharovsky E. Transcriptome and epigenome landscape of human cortical development modeled in organoids. Science 2018, 362 PMID: 30545853, PMCID: PMC6426303, DOI: 10.1126/science.aat6720.
• Comprehensive functional genomic resource and integrative model for the human brainWang D, Liu S, Warrell J, Won H, Shi X, Navarro FCP, Clarke D, Gu M, Emani P, Yang YT, Xu M, Gandal MJ, Lou S, Zhang J, Park JJ, Yan C, Rhie SK, Manakongtreecheep K, Zhou H, Nathan A, Peters M, Mattei E, Fitzgerald D, Brunetti T, Moore J, Jiang Y, Girdhar K, Hoffman GE, Kalayci S, Gümüş ZH, Crawford GE, Roussos P, Akbarian S, Jaffe A, White K, Weng Z, Sestan N, Geschwind D, Knowles J, Gerstein M, Ashley-Koch A, Crawford G, Garrett M, Song L, Safi A, Johnson G, Wray G, Reddy T, Goes F, Zandi P, Bryois J, Jaffe A, Price A, Ivanov N, Collado-Torres L, Hyde T, Burke E, Kleiman J, Tao R, Shin J, Akbarian S, Girdhar K, Jiang Y, Kundakovic M, Brown L, Kassim B, Park R, Wiseman J, Zharovsky E, Jacobov R, Devillers O, Flatow E, Hoffman G, Lipska B, Lewis D, Haroutunian V, Hahn C, Charney A, Dracheva S, Kozlenkov A, Belmont J, DelValle D, Francoeur N, Hadjimichael E, Pinto D, van Bakel H, Roussos P, Fullard J, Bendl J, Hauberg M, Mangravite L, Peters M, Chae Y, Peng J, Niu M, Wang X, Webster M, Beach T, Chen C, Jiang Y, Dai R, Shieh A, Liu C, Grennan K, Xia Y, Vadukapuram R, Wang Y, Fitzgerald D, Cheng L, Brown M, Brown M, Brunetti T, Goodman T, Alsayed M, Gandal M, Geschwind D, Won H, Polioudakis D, Wamsley B, Yin J, Hadzic T, De La Torre Ubieta L, Swarup V, Sanders S, State M, Werling D, An J, Sheppard B, Willsey A, White K, Ray M, Giase G, Kefi A, Mattei E, Purcaro M, Weng Z, Moore J, Pratt H, Huey J, Borrman T, Sullivan P, Giusti-Rodriguez P, Kim Y, Sullivan P, Szatkiewicz J, Rhie S, Armoskus C, Camarena A, Farnham P, Spitsyna V, Witt H, Schreiner S, Evgrafov O, Knowles J, Gerstein M, Liu S, Wang D, Navarro F, Warrell J, Clarke D, Emani P, Gu M, Shi X, Xu M, Yang Y, Kitchen R, Gürsoy G, Zhang J, Carlyle B, Nairn A, Li M, Pochareddy S, Sestan N, Skarica M, Li Z, Sousa A, Santpere G, Choi J, Zhu Y, Gao T, Miller D, Cherskov A, Yang M, Amiri A, Coppola G, Mariani J, Scuderi S, Szekely A, Vaccarino F, Wu F, Weissman S, Roychowdhury T, Abyzov A. Comprehensive functional genomic resource and integrative model for the human brain. Science 2018, 362 PMID: 30545857, PMCID: PMC6413328, DOI: 10.1126/science.aat8464.
• Transcriptome-wide isoform-level dysregulation in ASD, schizophrenia, and bipolar disorderGandal MJ, Zhang P, Hadjimichael E, Walker RL, Chen C, Liu S, Won H, van Bakel H, Varghese M, Wang Y, Shieh AW, Haney J, Parhami S, Belmont J, Kim M, Moran Losada P, Khan Z, Mleczko J, Xia Y, Dai R, Wang D, Yang YT, Xu M, Fish K, Hof PR, Warrell J, Fitzgerald D, White K, Jaffe AE, Peters M, Gerstein M, Liu C, Iakoucheva L, Pinto D, Geschwind D, Ashley-Koch A, Crawford G, Garrett M, Song L, Safi A, Johnson G, Wray G, Reddy T, Goes F, Zandi P, Bryois J, Jaffe A, Price A, Ivanov N, Collado-Torres L, Hyde T, Burke E, Kleiman J, Tao R, Shin J, Akbarian S, Girdhar K, Jiang Y, Kundakovic M, Brown L, Kassim B, Park R, Wiseman J, Zharovsky E, Jacobov R, Devillers O, Flatow E, Hoffman G, Lipska B, Lewis D, Haroutunian V, Hahn C, Charney A, Dracheva S, Kozlenkov A, Belmont J, DelValle D, Francoeur N, Hadjimichael E, Pinto D, van Bakel H, Roussos P, Fullard J, Bendl J, Hauberg M, Mangravite L, Peters M, Chae Y, Peng J, Niu M, Wang X, Webster M, Beach T, Chen C, Jiang Y, Dai R, Shieh A, Liu C, Grennan K, Xia Y, Vadukapuram R, Wang Y, Fitzgerald D, Cheng L, Brown M, Brown M, Brunetti T, Goodman T, Alsayed M, Gandal M, Geschwind D, Won H, Polioudakis D, Wamsley B, Yin J, Hadzic T, De La Torre Ubieta L, Swarup V, Sanders S, State M, Werling D, An J, Sheppard B, Willsey A, White K, Ray M, Giase G, Kefi A, Mattei E, Purcaro M, Weng Z, Moore J, Pratt H, Huey J, Borrman T, Sullivan P, Giusti-Rodriguez P, Kim Y, Sullivan P, Szatkiewicz J, Rhie S, Armoskus C, Camarena A, Farnham P, Spitsyna V, Witt H, Schreiner S, Evgrafov O, Knowles J, Gerstein M, Liu S, Wang D, Navarro F, Warrell J, Clarke D, Emani P, Gu M, Shi X, Xu M, Yang Y, Kitchen R, Gürsoy G, Zhang J, Carlyle B, Nairn A, Li M, Pochareddy S, Sestan N, Skarica M, Li Z, Sousa A, Santpere G, Choi J, Zhu Y, Gao T, Miller D, Cherskov A, Yang M, Amiri A, Coppola G, Mariani J, Scuderi S, Szekely A, Vaccarino F, Wu F, Weissman S, Roychowdhury T, Abyzov A. Transcriptome-wide isoform-level dysregulation in ASD, schizophrenia, and bipolar disorder. Science 2018, 362 PMID: 30545856, PMCID: PMC6443102, DOI: 10.1126/science.aat8127.
• Revealing the brain's molecular architectureAshley-Koch A, Crawford G, Garrett M, Song L, Safi A, Johnson G, Wray G, Reddy T, Goes F, Zandi P, Bryois J, Jaffe A, Price A, Ivanov N, Collado-Torres L, Hyde T, Burke E, Kleiman J, Tao R, Shin J, Akbarian S, Girdhar K, Jiang Y, Kundakovic M, Brown L, Kassim B, Park R, Wiseman J, Zharovsky E, Jacobov R, Devillers O, Flatow E, Hoffman G, Lipska B, Lewis D, Haroutunian V, Hahn C, Charney A, Dracheva S, Kozlenkov A, Belmont J, DelValle D, Francoeur N, Hadjimichael E, Pinto D, van Bakel H, Roussos P, Fullard J, Bendl J, Hauberg M, Mangravite L, Peters M, Chae Y, Peng J, Niu M, Wang X, Webster M, Beach T, Chen C, Jiang Y, Dai R, Shieh A, Liu C, Grennan K, Xia Y, Vadukapuram R, Wang Y, Fitzgerald D, Cheng L, Brown M, Brown M, Brunetti T, Goodman T, Alsayed M, Gandal M, Geschwind D, Won H, Polioudakis D, Wamsley B, Yin J, Hadzic T, De La Torre Ubieta L, Swarup V, Sanders S, State M, Werling D, An J, Sheppard B, Willsey A, White K, Ray M, Giase G, Kefi A, Mattei E, Purcaro M, Weng Z, Moore J, Pratt H, Huey J, Borrman T, Sullivan P, Giusti-Rodriguez P, Kim Y, Sullivan P, Szatkiewicz J, Rhie S, Armoskus C, Camarena A, Farnham P, Spitsyna V, Witt H, Schreiner S, Evgrafov O, Knowles J, Gerstein M, Liu S, Wang D, Navarro F, Warrell J, Clarke D, Emani P, Gu M, Shi X, Xu M, Yang Y, Kitchen R, Gürsoy G, Zhang J, Carlyle B, Nairn A, Li M, Pochareddy S, Sestan N, Skarica M, Li Z, Sousa A, Santpere G, Choi J, Zhu Y, Gao T, Miller D, Cherskov A, Yang M, Amiri A, Coppola G, Mariani J, Scuderi S, Szekely A, Vaccarino F, Wu F, Weissman S, Roychowdhury T, Abyzov A. Revealing the brain's molecular architecture. Science 2018, 362: 1262-1263. PMID: 30545881, DOI: 10.1126/science.362.6420.1262.
• Cell-Type-Specific Proteomics: A Neuroscience PerspectiveWilson RS, Nairn AC. Cell-Type-Specific Proteomics: A Neuroscience Perspective. Proteomes 2018, 6: 51. PMID: 30544872, PMCID: PMC6313874, DOI: 10.3390/proteomes6040051.
• Striatal Signaling Regulated by the H3R Histamine Receptor in a Mouse Model of tic PathophysiologyRapanelli M, Frick L, Jindachomthong K, Xu J, Ohtsu H, Nairn A, Pittenger C. Striatal Signaling Regulated by the H3R Histamine Receptor in a Mouse Model of tic Pathophysiology. Neuroscience 2018, 392: 172-179. PMID: 30278251, PMCID: PMC6204318, DOI: 10.1016/j.neuroscience.2018.09.035.
• Isoform-Level Interpretation of High-Throughput Proteomics Data Enabled by Deep Integration with RNA-seqCarlyle B, Kitchen RR, Zhang J, Wilson R, Lam T, Rozowsky JS, Williams KR, Sestan N, Gerstein M, Nairn AC. Isoform-Level Interpretation of High-Throughput Proteomics Data Enabled by Deep Integration with RNA-seq. Journal Of Proteome Research 2018, 17: 3431-3444. PMID: 30125121, PMCID: PMC6392456, DOI: 10.1021/acs.jproteome.8b00310.
• P1‐274: A TARGETED MASS‐SPECTROMETRY METHOD FOR QUANTIFICATION OF CEREBROSPINAL FLUID BIOMARKERS OF ALZHEIMER'S DISEASECarlyle B, Leslie S, Trombetta B, Nobuhara C, van Dyck C, Nairn A, Arnold S. P1‐274: A TARGETED MASS‐SPECTROMETRY METHOD FOR QUANTIFICATION OF CEREBROSPINAL FLUID BIOMARKERS OF ALZHEIMER'S DISEASE. Alzheimer's & Dementia 2018, 14: p387-p387. DOI: 10.1016/j.jalz.2018.06.280.
• P3‐088: THE AGING RHESUS MONKEY IS AN APPROPRIATE NEW ANIMAL MODEL FOR STUDYING THE ETIOLOGY AND TREATMENT OF TAU PATHOLOGY IN ASSOCIATION CORTEXArnsten A, Carlyle B, Leslie S, Preuss T, Crimins J, Datta D, Anita H, van Dyck C, Rosene D, Nairn A, Paspalas C. P3‐088: THE AGING RHESUS MONKEY IS AN APPROPRIATE NEW ANIMAL MODEL FOR STUDYING THE ETIOLOGY AND TREATMENT OF TAU PATHOLOGY IN ASSOCIATION CORTEX. Alzheimer's & Dementia 2018, 14: p1099-p1099. DOI: 10.1016/j.jalz.2018.06.1444.
• Striatin-1 is a B subunit of protein phosphatase PP2A that regulates dendritic arborization and spine development in striatal neuronsLi D, Musante V, Zhou W, Picciotto MR, Nairn AC. Striatin-1 is a B subunit of protein phosphatase PP2A that regulates dendritic arborization and spine development in striatal neurons. Journal Of Biological Chemistry 2018, 293: 11179-11194. PMID: 29802198, PMCID: PMC6052221, DOI: 10.1074/jbc.ra117.001519.
• Making brain proteomics true to typeWilson RS, Nairn AC. Making brain proteomics true to type. Nature Biotechnology 2018, 36: 149-150. PMID: 29406511, DOI: 10.1038/nbt.4077.
• A multiregional proteomic survey of the postnatal human brainCarlyle BC, Kitchen RR, Kanyo JE, Voss EZ, Pletikos M, Sousa AMM, Lam TT, Gerstein MB, Sestan N, Nairn AC. A multiregional proteomic survey of the postnatal human brain. Nature Neuroscience 2017, 20: 1787-1795. PMID: 29184206, PMCID: PMC5894337, DOI: 10.1038/s41593-017-0011-2.
• [P4–443]: PARKINSON's DISEASE‐ASSOCIATED MUTATIONS IN LRRK2 CAUSE CENTROSOMAL DEFECTS VIA RAB8A PHOSPHORYLATIONMadero‐Pérez J, Fdez E, Fernández B, Ordóñez A, Ramírez M, Gómez‐Suaga P, Waschbüsch D, Lobbestael E, Baekelandt V, Nairn A, Ruiz‐Martínez J, Aiastui A, de Munaín A, Lis P, Comptdaer T, Taymans J, Chartier‐Harlin M, Beilina A, Gonnelli A, Cookson M, Greggio E, Hilfiker S. [P4–443]: PARKINSON's DISEASE‐ASSOCIATED MUTATIONS IN LRRK2 CAUSE CENTROSOMAL DEFECTS VIA RAB8A PHOSPHORYLATION. Alzheimer's & Dementia 2017, 13: p1501-p1501. DOI: 10.1016/j.jalz.2017.07.604.
• Reciprocal regulation of ARPP-16 by PKA and MAST3 kinases provides a cAMP-regulated switch in protein phosphatase 2A inhibitionMusante V, Li L, Kanyo J, Lam TT, Colangelo CM, Cheng SK, Brody AH, Greengard P, Le Novère N, Nairn AC. Reciprocal regulation of ARPP-16 by PKA and MAST3 kinases provides a cAMP-regulated switch in protein phosphatase 2A inhibition. ELife 2017, 6: e24998. PMID: 28613156, PMCID: PMC5515580, DOI: 10.7554/elife.24998.
• ARPP-16 Is a Striatal-Enriched Inhibitor of Protein Phosphatase 2A Regulated by Microtubule-Associated Serine/Threonine Kinase 3 (Mast 3 Kinase)Andrade EC, Musante V, Horiuchi A, Matsuzaki H, Brody AH, Wu T, Greengard P, Taylor JR, Nairn AC. ARPP-16 Is a Striatal-Enriched Inhibitor of Protein Phosphatase 2A Regulated by Microtubule-Associated Serine/Threonine Kinase 3 (Mast 3 Kinase). Journal Of Neuroscience 2017, 37: 2709-2722. PMID: 28167675, PMCID: PMC5354324, DOI: 10.1523/jneurosci.4559-15.2017.
• Glutamate Counteracts Dopamine/PKA Signaling via Dephosphorylation of DARPP-32 Ser-97 and Alteration of Its Cytonuclear DistributionNishi A, Matamales M, Musante V, Valjent E, Kuroiwa M, Kitahara Y, Rebholz H, Greengard P, Girault JA, Nairn AC. Glutamate Counteracts Dopamine/PKA Signaling via Dephosphorylation of DARPP-32 Ser-97 and Alteration of Its Cytonuclear Distribution. Journal Of Biological Chemistry 2016, 292: 1462-1476. PMID: 27998980, PMCID: PMC5270488, DOI: 10.1074/jbc.m116.752402.
• Chapter 29 Regulation of Striatal Signaling by Protein PhosphatasesGirault J, Greengard P, Nairn A. Chapter 29 Regulation of Striatal Signaling by Protein Phosphatases. 2016, 24: 583-607. DOI: 10.1016/b978-0-12-802206-1.00029-5.
• ChemInform Abstract: Synthesis of Benzopentathiepin Analogues and Their Evaluation as Inhibitors of the Phosphatase STEP.Baguley T, Nairn A, Lombroso P, Ellman J. ChemInform Abstract: Synthesis of Benzopentathiepin Analogues and Their Evaluation as Inhibitors of the Phosphatase STEP. ChemInform 2015, 46: no-no. DOI: 10.1002/chin.201526245.
• STEP61 is a substrate of the E3 ligase parkin and is upregulated in Parkinson’s diseaseKurup PK, Xu J, Videira RA, Ononenyi C, Baltazar G, Lombroso PJ, Nairn AC. STEP61 is a substrate of the E3 ligase parkin and is upregulated in Parkinson’s disease. Proceedings Of The National Academy Of Sciences Of The United States Of America 2015, 112: 1202-1207. PMID: 25583483, PMCID: PMC4313846, DOI: 10.1073/pnas.1417423112.
• Correction to Substrate-Based Fragment Identification for the Development of Selective, Nonpeptidic Inhibitors of Striatal-Enriched Protein Tyrosine PhosphataseBaguley T, Xu H, Chatterjee M, Nairn A, Lombroso P, Ellman J. Correction to Substrate-Based Fragment Identification for the Development of Selective, Nonpeptidic Inhibitors of Striatal-Enriched Protein Tyrosine Phosphatase. Journal Of Medicinal Chemistry 2014, 57: 10564-10564. PMCID: PMC4364512, DOI: 10.1021/jm5018847.
• Decoding neuroproteomics: integrating the genome, translatome and functional anatomyKitchen RR, Rozowsky JS, Gerstein MB, Nairn AC. Decoding neuroproteomics: integrating the genome, translatome and functional anatomy. Nature Neuroscience 2014, 17: 1491-1499. PMID: 25349915, PMCID: PMC4737617, DOI: 10.1038/nn.3829.
• Synaptic NMDA receptor stimulation activates PP1 by inhibiting its phosphorylation by Cdk5Hou H, Sun L, Siddoway B, Petralia R, Yang H, Gu H, Nairn A, Xia H. Synaptic NMDA receptor stimulation activates PP1 by inhibiting its phosphorylation by Cdk5. The Journal Of General Physiology 2013, 142: 1426oia46. DOI: 10.1085/jgp.1426oia46.
• Recent advances in quantitative neuroproteomicsCraft GE, Chen A, Nairn AC. Recent advances in quantitative neuroproteomics. Methods 2013, 61: 186-218. PMID: 23623823, PMCID: PMC3891841, DOI: 10.1016/j.ymeth.2013.04.008.
• Folding of Intrinsically Disordered Protein Phosphatase 1 Regulatory ProteinsPeti W, C. Nairn A, Page R. Folding of Intrinsically Disordered Protein Phosphatase 1 Regulatory Proteins. Current Physical Chemistry 2012, 2: 107-114. DOI: 10.2174/1877947611202010107.
• Signaling Complex of Calcium/Calmodulin-Dependent Protein Kinase II Associated with the C-Terminal Domain of CaV2.1 ChannelsMagupalli V, Jiang X, Westenbroek R, Scheuer T, Soderling T, Nairn A, Catterall W. Signaling Complex of Calcium/Calmodulin-Dependent Protein Kinase II Associated with the C-Terminal Domain of CaV2.1 Channels. Biophysical Journal 2011, 100: 570a-571a. DOI: 10.1016/j.bpj.2010.12.3305.
• Beyond the Dopamine Receptor: Regulation and Roles of Serine/Threonine Protein PhosphatasesWalaas SI, Hemmings HC, Greengard P, Nairn AC. Beyond the Dopamine Receptor: Regulation and Roles of Serine/Threonine Protein Phosphatases. Frontiers In Neuroanatomy 2011, 5: 50. PMID: 21904525, PMCID: PMC3162284, DOI: 10.3389/fnana.2011.00050.
• Identification of Regulatory Phosphorylation Sites in Slack and Slick Sodium Activated Potassium (KNa) ChannelsFleming M, Kronengold J, Yan Y, Lam T, Gulcicek E, Sigworth F, Nairn A, Kaczmarek L. Identification of Regulatory Phosphorylation Sites in Slack and Slick Sodium Activated Potassium (KNa) Channels. Biophysical Journal 2010, 98: 316a. DOI: 10.1016/j.bpj.2009.12.1714.
• Chapter 79 The EF2K/MHCK/TRPM7 Family of Atypical Protein KinasesWiseman S, Wei F, Nairn A. Chapter 79 The EF2K/MHCK/TRPM7 Family of Atypical Protein Kinases. 2010, 587-599. DOI: 10.1016/b978-0-12-374145-5.00079-6.
• DARPP-32 Mediates the Actions of Multiple Drugs of AbuseSvenningsson P, Nairn A, Greengard P. DARPP-32 Mediates the Actions of Multiple Drugs of Abuse. 2008, 3-16. DOI: 10.1007/978-0-387-76678-2_1.
• Calcium dependent-regulation of neurite outgrowth mediated by a protein translational factor eEF2 within nerve growth conesIizuka A, Iketani M, Sengoku K, Nakamura F, Matsushita M, Nairn A, Goshima Y, Takei K. Calcium dependent-regulation of neurite outgrowth mediated by a protein translational factor eEF2 within nerve growth cones. Neuroscience Research 2007, 58: s204. DOI: 10.1016/j.neures.2007.06.924.
• 2‐Deoxyglucose and NMDA inhibit protein synthesis in neurons and regulate phosphorylation of elongation factor‐2 by distinct mechanismsMaus M, Torrens Y, Gauchy C, Bretin S, Nairn A, Glowinski J, Premont J. 2‐Deoxyglucose and NMDA inhibit protein synthesis in neurons and regulate phosphorylation of elongation factor‐2 by distinct mechanisms. Journal Of Neurochemistry 2006, 96: 815-824. PMID: 16405506, DOI: 10.1111/j.1471-4159.2005.03601.x.
• S.04.03 Allosteric changes of the NMDA receptor trap diffusible dopamine 1 receptors in spinesScott L, Zelenin S, Malmersjö S, Kowalewski J, Zettergren-Markus E, Nairn A, Greengard P, Brismar H, Aperia A. S.04.03 Allosteric changes of the NMDA receptor trap diffusible dopamine 1 receptors in spines. European Neuropsychopharmacology 2006, 16: s170. DOI: 10.1016/s0924-977x(06)70030-x.
• Allosteric changes of the NMDA receptor trap diffusible dopamine 1 receptors in spinesScott L, Zelenin S, Malmersjö S, Kowalewski J, Zettergren-Markus E, Nairn A, Greengard P, Brismar H, Aperia A. Allosteric changes of the NMDA receptor trap diffusible dopamine 1 receptors in spines. European Neuropsychopharmacology 2006, 16: s34-s35. DOI: 10.1016/s0924-977x(06)80043-x.
• A molecular switch for translational control in taste memory consolidationBelelovsky K, Elkobi A, Kaphzan H, Nairn A, Rosenblum K. A molecular switch for translational control in taste memory consolidation. European Journal Of Neuroscience 2005, 22: 2560-2568. PMID: 16307598, DOI: 10.1111/j.1460-9568.2005.04428.x.
• Control of the CFTR channel's gatesVergani P, Basso C, Mense M, Nairn A, Gadsby D. Control of the CFTR channel's gates. Biochemical Society Transactions 2005, 33: 1003-1007. DOI: 10.1042/bst0331003.
• Control of the CFTR channel's gates.Vergani P, Basso C, Mense M, Nairn A, Gadsby D. Control of the CFTR channel's gates. Biochemical Society Transactions 2005, 33: 1003-7. PMID: 16246032, PMCID: PMC2728124, DOI: 10.1042/bst20051003.
• A New Model of the Tautomycin—PP1 Complex that Is Not Analogous to the Corresponding Okadaic Acid Structure.Colby D, Liu W, Sheppeck J, Huang H, Nairn A, Chamberlin A. A New Model of the Tautomycin—PP1 Complex that Is Not Analogous to the Corresponding Okadaic Acid Structure. ChemInform 2003, 34: no-no. DOI: 10.1002/chin.200332198.
• Adenylyl cyclase-dependent form of chemical long-term potentiation triggers translational regulation at the elongation stepChotiner J, Khorasani H, Nairn A, O’Dell T, Watson J. Adenylyl cyclase-dependent form of chemical long-term potentiation triggers translational regulation at the elongation step. Neuroscience 2003, 116: 743-752. PMID: 12573716, DOI: 10.1016/s0306-4522(02)00797-2.
• Chapter 95 Atypical Protein Kinases The EF2/MHCK/ChaK Kinase FamilyNairn A. Chapter 95 Atypical Protein Kinases The EF2/MHCK/ChaK Kinase Family. 2003, 567-573. DOI: 10.1016/b978-012124546-7/50456-3.
• N-Methyl-D-aspartate receptor activation inhibits protein synthesis in cortical neurons independently of its ionic permeability propertiesGauchy C, Nairn A, Glowinski J, Prémont J. N-Methyl-D-aspartate receptor activation inhibits protein synthesis in cortical neurons independently of its ionic permeability properties. Neuroscience 2002, 114: 859-867. PMID: 12379242, DOI: 10.1016/s0306-4522(02)00322-6.
• Opposing Changes in Phosphorylation of Specific Sites in Synapsin I During Ca2+-Dependent Glutamate Release in Isolated Nerve TerminalsJovanovic J, Sihra T, Nairn A, Hemmings H, Greengard P, Czernik A. Opposing Changes in Phosphorylation of Specific Sites in Synapsin I During Ca2+-Dependent Glutamate Release in Isolated Nerve Terminals. Journal Of Neuroscience 2001, 21: 7944-7953. PMID: 11588168, PMCID: PMC6763853, DOI: 10.1523/jneurosci.21-20-07944.2001.
• A Novel Cyclin Provides a Link between Dopamine and RNA ProcessingNairn A, Greengard P. A Novel Cyclin Provides a Link between Dopamine and RNA Processing. Neuron 2001, 32: 174-176. PMID: 11683987, DOI: 10.1016/s0896-6273(01)00469-x.
• Regulation of cyclin-dependent kinase 5 and casein kinase 1 by metabotropic glutamate receptorsLiu F, Ma X, Ule J, Bibb J, Nishi A, DeMaggio A, Yan Z, Nairn A, Greengard P. Regulation of cyclin-dependent kinase 5 and casein kinase 1 by metabotropic glutamate receptors. Proceedings Of The National Academy Of Sciences Of The United States Of America 2001, 98: 11062-11068. PMID: 11572969, PMCID: PMC58683, DOI: 10.1073/pnas.191353898.
• Mechanisms for Increased Levels of Phosphorylation of Elongation Factor-2 during Hibernation in Ground Squirrels †Chen Y, Matsushita M, Nairn A, Damuni Z, Cai D, Frerichs K, Hallenbeck J. Mechanisms for Increased Levels of Phosphorylation of Elongation Factor-2 during Hibernation in Ground Squirrels †. Biochemistry 2001, 40: 11565-11570. PMID: 11560506, DOI: 10.1021/bi010649w.
• Changes in the phosphorylation of initiation factor eIF‐2α, elongation factor eEF‐2 and p70 S6 kinase after transient focal cerebral ischaemia in miceAlthausen S, Mengesdorf T, Mies G, Oláh L, Nairn A, Proud C, Paschen W. Changes in the phosphorylation of initiation factor eIF‐2α, elongation factor eEF‐2 and p70 S6 kinase after transient focal cerebral ischaemia in mice. Journal Of Neurochemistry 2001, 78: 779-787. PMID: 11520898, DOI: 10.1046/j.1471-4159.2001.00462.x.
• Angiotensin II regulates phosphorylation of translation elongation factor-2 in cardiac myocytesEverett A, Stoops T, Nairn A, Brautigan D. Angiotensin II regulates phosphorylation of translation elongation factor-2 in cardiac myocytes. AJP Heart And Circulatory Physiology 2001, 281: h161-h167. PMID: 11406481, DOI: 10.1152/ajpheart.2001.281.1.h161.
• Crystal Structure of the Atypical Protein Kinase Domain of a TRP Channel with Phosphotransferase ActivityYamaguchi H, Matsushita M, Nairn A, Kuriyan J. Crystal Structure of the Atypical Protein Kinase Domain of a TRP Channel with Phosphotransferase Activity. Molecular Cell 2001, 7: 1047-1057. PMID: 11389851, DOI: 10.1016/s1097-2765(01)00256-8.
• Letter to the Editor: Backbone 1H, 15N, and 13C resonance assignments of ARPP-19Huang H, Chen Y, Horiuchi A, Tsai L, Liu H, Chyan C, Hsieh M, Liu C, Lin F, Greengard P, Nairn A, Shiao M, Lin T. Letter to the Editor: Backbone 1H, 15N, and 13C resonance assignments of ARPP-19. Journal Of Biomolecular NMR 2001, 19: 383-384. PMID: 11370788, DOI: 10.1023/a:1011214512601.
• ARPP‐16/ARPP‐19: a highly conserved family of cAMP‐regulated phosphoproteinsDulubova I, Horiuchi A, Snyder G, Girault J, Czernik A, Shao L, Ramabhadran R, Greengard P, Nairn A. ARPP‐16/ARPP‐19: a highly conserved family of cAMP‐regulated phosphoproteins. Journal Of Neurochemistry 2001, 77: 229-238. DOI: 10.1046/j.1471-4159.2001.00191.x.
• ARPP-16/ARPP-19: a highly conserved family of cAMP-regulated phosphoproteins.Dulubova I, Horiuchi A, Snyder G, Girault J, Czernik A, Shao L, Ramabhadran R, Greengard P, Nairn A. ARPP-16/ARPP-19: a highly conserved family of cAMP-regulated phosphoproteins. Journal Of Neurochemistry 2001, 77: 229-38. PMID: 11279279, DOI: 10.1046/j.1471-4159.2001.t01-1-00191.x.
• TARPP, a novel protein that accompanies TCR gene rearrangement and thymocyte educationKisielow J, Nairn A, Karjalainen K. TARPP, a novel protein that accompanies TCR gene rearrangement and thymocyte education. European Journal Of Immunology 2001, 31: 1141-1149. PMID: 11298339, DOI: 10.1002/1521-4141(200104)31:4<1141::aid-immu1141>3.0.co;2-r.
• Protein phosphatase 1 regulation by inhibitors and targeting subunitsWatanabe T, Huang H, Horiuchi A, da Cruze Silva E, Hsieh-Wilson L, Allen P, Shenolikar S, Greengard P, Nairn A. Protein phosphatase 1 regulation by inhibitors and targeting subunits. Proceedings Of The National Academy Of Sciences Of The United States Of America 2001, 98: 3080-3085. PMID: 11248035, PMCID: PMC30610, DOI: 10.1073/pnas.051003898.
• Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5Bibb J, Chen J, Taylor J, Svenningsson P, Nishi A, Snyder G, Yan Z, Sagawa Z, Ouimet C, Nairn A, Nestler E, Greengard P. Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5. Nature 2001, 410: 376-380. PMID: 11268215, DOI: 10.1038/35066591.
• Inhibition of protein synthesis in cortical neurons during exposure to hydrogen peroxideAlirezaei M, Marin P, Nairn A, Glowinski J, Prémont J. Inhibition of protein synthesis in cortical neurons during exposure to hydrogen peroxide. Journal Of Neurochemistry 2001, 76: 1080-1088. PMID: 11181828, DOI: 10.1046/j.1471-4159.2001.00105.x.
• Auto‐inhibition of Ca2+/calmodulin‐dependent protein kinase II by its ATP‐binding domainLengyel I, Nairn A, McCluskey A, Tóth G, Penke B, Rostas J. Auto‐inhibition of Ca2+/calmodulin‐dependent protein kinase II by its ATP‐binding domain. Journal Of Neurochemistry 2001, 76: 1066-1072. PMID: 11181826, DOI: 10.1046/j.1471-4159.2001.00139.x.
• Phosphorylation of Protein Phosphatase Inhibitor-1 by Cdk5*Bibb J, Nishi A, O'Callaghan J, Ule J, Lan M, Snyder G, Horiuchi A, Saito T, Hisanaga S, Czernik A, Nairn A, Greengard P. Phosphorylation of Protein Phosphatase Inhibitor-1 by Cdk5*. Journal Of Biological Chemistry 2001, 276: 14490-14497. PMID: 11278334, DOI: 10.1074/jbc.m007197200.
• Decreased levels of ARPP-19 and PKA in brains of Down syndrome and Alzheimer’s diseaseKim S, Nairn A, Cairns N, Lubec G. Decreased levels of ARPP-19 and PKA in brains of Down syndrome and Alzheimer’s disease. 2001, 263-272. PMID: 11771749, DOI: 10.1007/978-3-7091-6262-0_21.
• Elongation Factor-2 Phosphorylation and the Regulation of Protein Synthesis by CalciumNairn A, Matsushita M, Nastiuk K, Horiuchi A, Mitsui K, Shimizu Y, Palfrey H. Elongation Factor-2 Phosphorylation and the Regulation of Protein Synthesis by Calcium. 2001, 27: 91-129. PMID: 11575162, DOI: 10.1007/978-3-662-09889-9_4.
• Amplification of dopaminergic signaling by a positive feedback loopNishi A, Bibb J, Snyder G, Higashi H, Nairn A, Greengard P. Amplification of dopaminergic signaling by a positive feedback loop. Proceedings Of The National Academy Of Sciences Of The United States Of America 2000, 97: 12840-12845. PMID: 11050161, PMCID: PMC18851, DOI: 10.1073/pnas.220410397.
• Severed Channels Probe Regulation of Gating of Cystic Fibrosis Transmembrane Conductance Regulator by Its Cytoplasmic DomainsCsanády L, Chan K, Seto-Young D, Kopsco D, Nairn A, Gadsby D. Severed Channels Probe Regulation of Gating of Cystic Fibrosis Transmembrane Conductance Regulator by Its Cytoplasmic Domains. The Journal Of General Physiology 2000, 116: 477-500. PMID: 10962022, PMCID: PMC2233695, DOI: 10.1085/jgp.116.3.477.
• Letter to the Editor: Backbone 1H, 15N, and 13C resonance assignments of inhibitor-2 – a protein inhibitor of protein phosphatase-1Huang H, Chen Y, Tsai L, Wang H, Lin F, Horiuchi A, Greengard P, Nairn A, Shiao M, Lin T. Letter to the Editor: Backbone 1H, 15N, and 13C resonance assignments of inhibitor-2 – a protein inhibitor of protein phosphatase-1. Journal Of Biomolecular NMR 2000, 17: 359-360. PMID: 11014604, DOI: 10.1023/a:1008355428294.
• The Dopamine/D1 Receptor Mediates the Phosphorylation and Inactivation of the Protein Tyrosine Phosphatase STEP via a PKA-Dependent PathwayPaul S, Snyder G, Yokakura H, Picciotto M, Nairn A, Lombroso P. The Dopamine/D1 Receptor Mediates the Phosphorylation and Inactivation of the Protein Tyrosine Phosphatase STEP via a PKA-Dependent Pathway. Journal Of Neuroscience 2000, 20: 5630-5638. PMID: 10908600, PMCID: PMC6772528, DOI: 10.1523/jneurosci.20-15-05630.2000.
• Drugs of abuse modulate the phosphorylation of ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in the basal gangliaCaporaso G, Bibb J, Snyder G, Valle C, Rakhilin S, Fienberg A, Hemmings H, Nairn A, Greengard P. Drugs of abuse modulate the phosphorylation of ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in the basal ganglia. Neuropharmacology 2000, 39: 1637-1644. PMID: 10854908, DOI: 10.1016/s0028-3908(99)00230-0.
• Severed Molecules Functionally Define the Boundaries of the Cystic Fibrosis Transmembrane Conductance Regulator's Nh2-Terminal Nucleotide Binding DomainChan K, Csanády L, Seto-Young D, Nairn A, Gadsby D. Severed Molecules Functionally Define the Boundaries of the Cystic Fibrosis Transmembrane Conductance Regulator's Nh2-Terminal Nucleotide Binding Domain. The Journal Of General Physiology 2000, 116: 163-180. PMID: 10919864, PMCID: PMC2229491, DOI: 10.1085/jgp.116.2.163.
• Novel compounds, ‘1,3-selenazine derivatives’ as specific inhibitors of eukaryotic elongation factor-2 kinaseCho S, Koketsu M, Ishihara H, Matsushita M, Nairn A, Fukazawa H, Uehara Y. Novel compounds, ‘1,3-selenazine derivatives’ as specific inhibitors of eukaryotic elongation factor-2 kinase. Biochimica Et Biophysica Acta 2000, 1475: 207-215. PMID: 10913818, DOI: 10.1016/s0304-4165(00)00061-1.
• Regulation of Phosphorylation of the GluR1 AMPA Receptor in the Neostriatum by Dopamine and Psychostimulants In VivoSnyder G, Allen P, Fienberg A, Valle C, Huganir R, Nairn A, Greengard P. Regulation of Phosphorylation of the GluR1 AMPA Receptor in the Neostriatum by Dopamine and Psychostimulants In Vivo. Journal Of Neuroscience 2000, 20: 4480-4488. PMID: 10844017, PMCID: PMC6772453, DOI: 10.1523/jneurosci.20-12-04480.2000.
• Cellular Mechanisms Regulating Protein Phosphatase-1 A KEY FUNCTIONAL INTERACTION BETWEEN INHIBITOR-2 AND THE TYPE 1 PROTEIN PHOSPHATASE CATALYTIC SUBUNIT*Frederick D, Huang H, Yang J, Helps N, Cohen P, Nairn A, DePaoli-Roach A, Tatchell K, Connor J, Shenolikar S. Cellular Mechanisms Regulating Protein Phosphatase-1 A KEY FUNCTIONAL INTERACTION BETWEEN INHIBITOR-2 AND THE TYPE 1 PROTEIN PHOSPHATASE CATALYTIC SUBUNIT*. Journal Of Biological Chemistry 2000, 275: 18670-18675. PMID: 10748125, DOI: 10.1074/jbc.m909312199.
• Severe deficiencies in dopamine signaling in presymptomatic Huntington's disease miceBibb J, Yan Z, Svenningsson P, Snyder G, Pieribone V, Horiuchi A, Nairn A, Messer A, Greengard P. Severe deficiencies in dopamine signaling in presymptomatic Huntington's disease mice. Proceedings Of The National Academy Of Sciences Of The United States Of America 2000, 97: 6809-6814. PMID: 10829080, PMCID: PMC18747, DOI: 10.1073/pnas.120166397.
• Prostaglandin E2 interaction with AVP: effects on AQP2 phosphorylation and distributionZelenina M, Christensen B, Palmér J, Nairn A, Nielsen S, Aperia A. Prostaglandin E2 interaction with AVP: effects on AQP2 phosphorylation and distribution. American Journal Of Physiology. Renal Physiology 2000, 278: f388-f394. PMID: 10710543, DOI: 10.1152/ajprenal.2000.278.3.f388.
• NMDA receptor-mediated control of protein synthesis at developing synapsesScheetz A, Nairn A, Constantine-Paton M. NMDA receptor-mediated control of protein synthesis at developing synapses. Nature Neuroscience 2000, 3: 211-216. PMID: 10700251, DOI: 10.1038/72915.
• Regulation of protein phosphatase-1Aggen J, Nairn A, Chamberlin R. Regulation of protein phosphatase-1. Cell Chemical Biology 2000, 7: r13-r23. PMID: 10662690, DOI: 10.1016/s1074-5521(00)00069-7.
• Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neuronsBibb J, Snyder G, Nishi A, Yan Z, Meijer L, Fienberg A, Tsai L, Kwon Y, Girault J, Czernik A, Huganir R, Hemmings H, Nairn A, Greengard P. Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons. Nature 1999, 402: 669-671. PMID: 10604473, DOI: 10.1038/45251.
• Modulation of a calcium/calmodulin-dependent protein kinase cascade by retinoic acid during neutrophil maturationLawson N, Zain M, Zibello T, Picciotto M, Nairn A, Berliner N. Modulation of a calcium/calmodulin-dependent protein kinase cascade by retinoic acid during neutrophil maturation. Experimental Hematology 1999, 27: 1682-1690. PMID: 10560916, DOI: 10.1016/s0301-472x(99)00108-3.
• Zinc Inhibits Protein Synthesis in Neurons POTENTIAL ROLE OF PHOSPHORYLATION OF TRANSLATION INITIATION FACTOR-2α*Alirezaei M, Nairn A, Glowinski J, Prémont J, Marin P. Zinc Inhibits Protein Synthesis in Neurons POTENTIAL ROLE OF PHOSPHORYLATION OF TRANSLATION INITIATION FACTOR-2α*. Journal Of Biological Chemistry 1999, 274: 32433-32438. PMID: 10542287, DOI: 10.1074/jbc.274.45.32433.
• The expression of Ca2+/calmodulin-dependent protein kinase I in rat retina is regulated by light stimulationTsumura T, Murata A, Yamaguchi F, Sugimoto K, Hasegawa E, Hatase O, Nairn A, Tokuda M. The expression of Ca2+/calmodulin-dependent protein kinase I in rat retina is regulated by light stimulation. Vision Research 1999, 39: 3165-3173. PMID: 10615488, DOI: 10.1016/s0042-6989(99)00063-2.
• Regulation of Neurabin I Interaction with Protein Phosphatase 1 by Phosphorylation †McAvoy T, Allen P, Obaishi H, Nakanishi H, Takai Y, Greengard P, Nairn A, Hemmings H. Regulation of Neurabin I Interaction with Protein Phosphatase 1 by Phosphorylation †. Biochemistry 1999, 38: 12943-12949. PMID: 10504266, DOI: 10.1021/bi991227d.
• Mutation of Tyr307 and Leu309 in the Protein Phosphatase 2A Catalytic Subunit Favors Association with the α4 Subunit Which Promotes Dephosphorylation of Elongation Factor-2 †Chung H, Nairn A, Murata K, Brautigan D. Mutation of Tyr307 and Leu309 in the Protein Phosphatase 2A Catalytic Subunit Favors Association with the α4 Subunit Which Promotes Dephosphorylation of Elongation Factor-2 †. Biochemistry 1999, 38: 10371-10376. PMID: 10441131, DOI: 10.1021/bi990902g.
• Beyond the Dopamine Receptor the DARPP-32/Protein Phosphatase-1 CascadeGreengard P, Allen P, Nairn A. Beyond the Dopamine Receptor the DARPP-32/Protein Phosphatase-1 Cascade. Neuron 1999, 23: 435-447. PMID: 10433257, DOI: 10.1016/s0896-6273(00)80798-9.
• Requirement for DARPP‐32 in mediating effect of dopamine D2 receptor activationNishi A, Snyder G, Fienberg A, Fisone G, Aperia A, Nairn A, Greengard P. Requirement for DARPP‐32 in mediating effect of dopamine D2 receptor activation. European Journal Of Neuroscience 1999, 11: 2589-2592. PMID: 10383649, DOI: 10.1046/j.1460-9568.1999.00724.x.
• Role of Phosphorylation of Alzheimer’s Amyloid Precursor Protein during Neuronal DifferentiationAndo K, Oishi M, Takeda S, Iijima K, Isohara T, Nairn A, Kirino Y, Greengard P, Suzuki T. Role of Phosphorylation of Alzheimer’s Amyloid Precursor Protein during Neuronal Differentiation. Journal Of Neuroscience 1999, 19: 4421-4427. PMID: 10341243, PMCID: PMC6782598, DOI: 10.1523/jneurosci.19-11-04421.1999.
• Modulation of GT-1 DNA-binding activity by calcium-dependent phosphorylationMaréchal E, Hiratsuka K, Delgado J, Nairn A, Qin J, Chait B, Chua N. Modulation of GT-1 DNA-binding activity by calcium-dependent phosphorylation. Plant Molecular Biology 1999, 40: 373-386. PMID: 10437822, DOI: 10.1023/a:1006131330930.
• Phosphorylation of the Cytoplasmic Domain of Alzheimer's β-Amyloid Precursor Protein at Ser655 by a Novel Protein KinaseIsohara T, Horiuchi A, Watanabe T, Ando K, Czernik A, Uno I, Greengard P, Nairn A, Suzuki T. Phosphorylation of the Cytoplasmic Domain of Alzheimer's β-Amyloid Precursor Protein at Ser655 by a Novel Protein Kinase. Biochemical And Biophysical Research Communications 1999, 258: 300-305. PMID: 10329382, DOI: 10.1006/bbrc.1999.0637.
• Role of Calcineurin and Protein Phosphatase‐2A in the Regulation of DARPP‐32 Dephosphorylation in Neostriatal NeuronsNishi A, Snyder G, Nairn A, Greengard P. Role of Calcineurin and Protein Phosphatase‐2A in the Regulation of DARPP‐32 Dephosphorylation in Neostriatal Neurons. Journal Of Neurochemistry 1999, 72: 2015-2021. PMID: 10217279, DOI: 10.1046/j.1471-4159.1999.0722015.x.
• Phylogenetically conserved CK‐II phosphorylation site of the murine homeodomain protein Hoxb‐6Fienberg A, Nordstedt C, Belting H, Czernik A, Nairn A, Gandy S, Greengard P, Ruddle F. Phylogenetically conserved CK‐II phosphorylation site of the murine homeodomain protein Hoxb‐6. Journal Of Experimental Zoology 1999, 285: 76-84. PMID: 10327653, DOI: 10.1002/(sici)1097-010x(19990415)285:1<76::aid-jez9>3.0.co;2-k.
• Angiotensin II Regulates Cardiac Myocyte Protein Synthesis by Activation of Elongation Factor 2Everett A, Nairn A, Cho H, Stoops T. Angiotensin II Regulates Cardiac Myocyte Protein Synthesis by Activation of Elongation Factor 2. Pediatric Research 1999, 45: 22-22. DOI: 10.1203/00006450-199904020-00138.
• Inhibition of the Ca2+/Calmodulin-dependent Protein Kinase I Cascade by cAMP-dependent Protein Kinase*Matsushita M, Nairn A. Inhibition of the Ca2+/Calmodulin-dependent Protein Kinase I Cascade by cAMP-dependent Protein Kinase*. Journal Of Biological Chemistry 1999, 274: 10086-10093. PMID: 10187789, DOI: 10.1074/jbc.274.15.10086.
• Characterization of the Neuronal Targeting Protein Spinophilin and Its Interactions with Protein Phosphatase-1 †Hsieh-Wilson L, Allen P, Watanabe T, Nairn A, Greengard P. Characterization of the Neuronal Targeting Protein Spinophilin and Its Interactions with Protein Phosphatase-1 †. Biochemistry 1999, 38: 4365-4373. PMID: 10194355, DOI: 10.1021/bi982900m.
• Molecular identification of human G-substrate, a possible downstream component of the cGMP-dependent protein kinase cascade in cerebellar Purkinje cellsEndo S, Suzuki M, Sumi M, Nairn A, Morita R, Yamakawa K, Greengard P, Ito M. Molecular identification of human G-substrate, a possible downstream component of the cGMP-dependent protein kinase cascade in cerebellar Purkinje cells. Proceedings Of The National Academy Of Sciences Of The United States Of America 1999, 96: 2467-2472. PMID: 10051666, PMCID: PMC26808, DOI: 10.1073/pnas.96.5.2467.
• Characterization of the Inhibition of Protein Phosphatase-1 by DARPP-32 and Inhibitor-2*Huang H, Horiuchi A, Watanabe T, Shih S, Tsay H, Li H, Greengard P, Nairn A. Characterization of the Inhibition of Protein Phosphatase-1 by DARPP-32 and Inhibitor-2*. Journal Of Biological Chemistry 1999, 274: 7870-7878. PMID: 10075680, DOI: 10.1074/jbc.274.12.7870.
• The design, synthesis, and biological evaluation of analogues of the serine-threonine protein phosphatase 1 and 2A selective inhibitor microcystin LA: rational modifications imparting PP1 selectivityAggen J, Humphrey J, Gauss C, Huang H, Nairn A, Chamberlin A. The design, synthesis, and biological evaluation of analogues of the serine-threonine protein phosphatase 1 and 2A selective inhibitor microcystin LA: rational modifications imparting PP1 selectivity. Bioorganic & Medicinal Chemistry 1999, 7: 543-564. PMID: 10220039, DOI: 10.1016/s0968-0896(98)00254-5.
• Arginine vasopressin stimulates phosphorylation of aquaporin-2 in rat renal tissueNishimoto G, Zelenina M, Li D, Yasui M, Aperia A, Nielsen S, Nairn A. Arginine vasopressin stimulates phosphorylation of aquaporin-2 in rat renal tissue. American Journal Of Physiology 1999, 276: f254-f259. PMID: 9950956, DOI: 10.1152/ajprenal.1999.276.2.f254.
• Control of CFTR Channel Gating by Phosphorylation and Nucleotide HydrolysisGADSBY D, NAIRN A. Control of CFTR Channel Gating by Phosphorylation and Nucleotide Hydrolysis. Physiological Reviews 1999, 79: s77-s107. PMID: 9922377, DOI: 10.1152/physrev.1999.79.1.s77.
• Regulation of CFTR Cl- ion channels by phosphorylation and dephosphorylation.Gadsby D, Nairn A. Regulation of CFTR Cl- ion channels by phosphorylation and dephosphorylation. 1999, 33: 79-106. PMID: 10218115, DOI: 10.1016/s1040-7952(99)80006-8.
• Protein phosphatase 1 modulation of neostriatal AMPA channels: regulation by DARPP–32 and spinophilinYan Z, Hsieh–Wilson L, Feng J, Tomizawa K, Allen P, Fienberg A, Nairn A, Greengard P. Protein phosphatase 1 modulation of neostriatal AMPA channels: regulation by DARPP–32 and spinophilin. Nature Neuroscience 1999, 2: 13-17. PMID: 10195174, DOI: 10.1038/4516.
• Ca2+/calmodulin-dependent kinase II mediates simultaneous enhancement of gap-junctional conductance and glutamatergic transmissionPereda A, Bell T, Chang B, Czernik A, Nairn A, Soderling T, Faber D. Ca2+/calmodulin-dependent kinase II mediates simultaneous enhancement of gap-junctional conductance and glutamatergic transmission. Proceedings Of The National Academy Of Sciences Of The United States Of America 1998, 95: 13272-13277. PMID: 9789078, PMCID: PMC23780, DOI: 10.1073/pnas.95.22.13272.
• ATP hydrolysis cycles and the gating of CFTR Cl- channels.Gadsby D, Dousmanis A, Nairn A. ATP hydrolysis cycles and the gating of CFTR Cl- channels. Acta Physiologica Scandinavica. Supplementum 1998, 643: 247-56. PMID: 9789567.
• Characterization of the Mechanism of Regulation of Ca2+/ Calmodulin-dependent Protein Kinase I by Calmodulin and by Ca2+/Calmodulin-dependent Protein Kinase Kinase*Matsushita M, Nairn A. Characterization of the Mechanism of Regulation of Ca2+/ Calmodulin-dependent Protein Kinase I by Calmodulin and by Ca2+/Calmodulin-dependent Protein Kinase Kinase*. Journal Of Biological Chemistry 1998, 273: 21473-21481. PMID: 9705275, DOI: 10.1074/jbc.273.34.21473.
• The DARPP-32/protein phosphatase-1 cascade: a model for signal integration1Published on the World Wide Web on 22 January 1998.1Greengard P, Nairn A, Girault J, Ouimet C, Snyder G, Fisone G, Allen P, Fienberg A, Nishi A. The DARPP-32/protein phosphatase-1 cascade: a model for signal integration1Published on the World Wide Web on 22 January 1998.1. Brain Research Reviews 1998, 26: 274-284. PMID: 9651542, DOI: 10.1016/s0165-0173(97)00057-x.
• Cellular Localization of Calmodulin-dependent Protein Kinases I and II to A-cells and D-cells of the Endocrine PancreasMatovcik L, Nairn A, Gorelick F. Cellular Localization of Calmodulin-dependent Protein Kinases I and II to A-cells and D-cells of the Endocrine Pancreas. Journal Of Histochemistry & Cytochemistry 1998, 46: 519-526. PMID: 9524198, DOI: 10.1177/002215549804600412.
• Actions of Genistein on Cystic Fibrosis Transmembrane Conductance Regulator Channel GatingWang F, Zeltwanger S, Yang I, Nairn A, Hwang T. Actions of Genistein on Cystic Fibrosis Transmembrane Conductance Regulator Channel Gating. The Journal Of General Physiology 1998, 111: 477-490. PMID: 9482713, PMCID: PMC2217116, DOI: 10.1085/jgp.111.3.477.
• Isolation and Characterization of PNUTS, a Putative Protein Phosphatase 1 Nuclear Targeting Subunit*Allen P, Kwon Y, Nairn A, Greengard P. Isolation and Characterization of PNUTS, a Putative Protein Phosphatase 1 Nuclear Targeting Subunit*. Journal Of Biological Chemistry 1998, 273: 4089-4095. PMID: 9461602, DOI: 10.1074/jbc.273.7.4089.
• Regulation of Secretion of Alzheimer Amyloid Precursor Protein by the Mitogen‐Activated Protein Kinase CascadeDesdouits‐Magnen J, Desdouits F, Takeda S, Syu L, Saltiel A, Buxbaum J, Czernik A, Nairn A, Greengard P. Regulation of Secretion of Alzheimer Amyloid Precursor Protein by the Mitogen‐Activated Protein Kinase Cascade. Journal Of Neurochemistry 1998, 70: 524-530. PMID: 9453546, DOI: 10.1046/j.1471-4159.1998.70020524.x.
• Structure and regulation of Ca2+/calmodulin dependent protein kinase III (elongation factor 2 kinase)Matsushita M, Moriwaki A, Kondo E, Matsui H, Nairn A. Structure and regulation of Ca2+/calmodulin dependent protein kinase III (elongation factor 2 kinase). Neuroscience Research 1998, 31: s124. DOI: 10.1016/s0168-0102(98)82003-8.
• N-methyl-d-aspartate receptor activation and visual activity induce elongation factor-2 phosphorylation in amphibian tecta: A role for N-methyl-d-aspartate receptors in controlling protein synthesisScheetz A, Nairn A, Constantine-Paton M. N-methyl-d-aspartate receptor activation and visual activity induce elongation factor-2 phosphorylation in amphibian tecta: A role for N-methyl-d-aspartate receptors in controlling protein synthesis. Proceedings Of The National Academy Of Sciences Of The United States Of America 1997, 94: 14770-14775. PMID: 9405688, PMCID: PMC25112, DOI: 10.1073/pnas.94.26.14770.
• Regulation of rat Na+-K+-ATPase activity by PKC is modulated by state of phosphorylation of Ser-943 by PKACheng X, Höög J, Nairn A, Greengard P, Aperia A. Regulation of rat Na+-K+-ATPase activity by PKC is modulated by state of phosphorylation of Ser-943 by PKA. American Journal Of Physiology 1997, 273: c1981-c1986. PMID: 9435504, DOI: 10.1152/ajpcell.1997.273.6.c1981.
• The Regulation of Glycogen Synthase by Protein Phosphatase 1 in 3T3-L1 Adipocytes EVIDENCE FOR A POTENTIAL ROLE FOR DARPP-32 IN INSULIN ACTION*Brady M, Nairn A, Saltiel A. The Regulation of Glycogen Synthase by Protein Phosphatase 1 in 3T3-L1 Adipocytes EVIDENCE FOR A POTENTIAL ROLE FOR DARPP-32 IN INSULIN ACTION*. Journal Of Biological Chemistry 1997, 272: 29698-29703. PMID: 9368038, DOI: 10.1074/jbc.272.47.29698.
• A molecular modeling analysis of the binding interactions between the okadaic acid class of natural product inhibitors and the ser-thr phosphatases, PP1 and PP2AGauss C, Sheppeck J, Nairn A, Chamberlin R. A molecular modeling analysis of the binding interactions between the okadaic acid class of natural product inhibitors and the ser-thr phosphatases, PP1 and PP2A. Bioorganic & Medicinal Chemistry 1997, 5: 1751-1773. PMID: 9354231, DOI: 10.1016/s0968-0896(97)00145-4.
• Mutation of the Protein Kinase C Phosphorylation Site on Rat α1 Na+,K+-ATPase Alters Regulation of Intracellular Na+ and pH and Influences Cell Shape and Adhesiveness*Belusa R, Wang Z, Matsubara T, Sahlgren B, Dulubova I, Nairn A, Ruoslahti E, Greengard P, Aperia A. Mutation of the Protein Kinase C Phosphorylation Site on Rat α1 Na+,K+-ATPase Alters Regulation of Intracellular Na+ and pH and Influences Cell Shape and Adhesiveness*. Journal Of Biological Chemistry 1997, 272: 20179-20184. PMID: 9242694, DOI: 10.1074/jbc.272.32.20179.
• Phosphorylation of Connexin43 and the Regulation of Neonatal Rat Cardiac Myocyte Gap JunctionsSáez J, Nairn A, Czernik A, Fishman G, Spray D, Hertzberg E. Phosphorylation of Connexin43 and the Regulation of Neonatal Rat Cardiac Myocyte Gap Junctions. Journal Of Molecular And Cellular Cardiology 1997, 29: 2131-2145. PMID: 9281445, DOI: 10.1006/jmcc.1997.0447.
• Glutamate-Dependent Phosphorylation of Elongation Factor-2 and Inhibition of Protein Synthesis in NeuronsMarin P, Nastiuk K, Daniel N, Girault J, Czernik A, Glowinski J, Nairn A, Prémont J. Glutamate-Dependent Phosphorylation of Elongation Factor-2 and Inhibition of Protein Synthesis in Neurons. Journal Of Neuroscience 1997, 17: 3445-3454. PMID: 9133370, PMCID: PMC6573691, DOI: 10.1523/jneurosci.17-10-03445.1997.
• Widespread Neuronal Ectopia Associated with Secondary Defects in Cerebrocortical Chondroitin Sulfate Proteoglycans and Basal Lamina in MARCKS-Deficient MiceBlackshear P, Silver J, Nairn A, Sulik K, Squier M, Stumpo D, Tuttle J. Widespread Neuronal Ectopia Associated with Secondary Defects in Cerebrocortical Chondroitin Sulfate Proteoglycans and Basal Lamina in MARCKS-Deficient Mice. Experimental Neurology 1997, 145: 46-61. PMID: 9184108, DOI: 10.1006/exnr.1997.6475.
• Site-directed mutagenesis of amino acid residues of protein phosphatase 1 involved in catalysis and inhibitor bindingHuang H, Horiuchi A, Goldberg J, Greengard P, Nairn A. Site-directed mutagenesis of amino acid residues of protein phosphatase 1 involved in catalysis and inhibitor binding. Proceedings Of The National Academy Of Sciences Of The United States Of America 1997, 94: 3530-3535. PMID: 9108010, PMCID: PMC20473, DOI: 10.1073/pnas.94.8.3530.
• Characterization of the interaction between DARPP-32 and protein phosphatase 1 (PP-1): DARPP-32 peptides antagonize the interaction of PP-1 with binding proteinsKwon Y, Huang H, Desdouits F, Girault J, Greengard P, Nairn A. Characterization of the interaction between DARPP-32 and protein phosphatase 1 (PP-1): DARPP-32 peptides antagonize the interaction of PP-1 with binding proteins. Proceedings Of The National Academy Of Sciences Of The United States Of America 1997, 94: 3536-3541. PMID: 9108011, PMCID: PMC20474, DOI: 10.1073/pnas.94.8.3536.
• Phosphorylation of Alzheimer β-Amyloid Precursor-like Proteins †Suzuki T, Ando K, Isohara T, Oishi M, Lim G, Satoh Y, Wasco W, Tanzi R, Nairn A, Greengard P, Gandy S, Kirino Y. Phosphorylation of Alzheimer β-Amyloid Precursor-like Proteins †. Biochemistry 1997, 36: 4643-4649. PMID: 9109675, DOI: 10.1021/bi962618k.
• Cell cycle-dependent phosphorylation of mammalian protein phosphatase 1 by cdc2 kinaseKwon Y, Lee S, Choi Y, Greengard P, Nairn A. Cell cycle-dependent phosphorylation of mammalian protein phosphatase 1 by cdc2 kinase. Proceedings Of The National Academy Of Sciences Of The United States Of America 1997, 94: 2168-2173. PMID: 9122166, PMCID: PMC20059, DOI: 10.1073/pnas.94.6.2168.
• The Cytoplasmic Domain of Alzheimer’s Amyloid Precursor Protein Is Phosphorylated at Thr654, Ser655, and Thr668 in Adult Rat Brain and Cultured CellsOishi M, Nairn A, Czernik A, Lim G, Isohara T, Gandy S, Greengard P, Suzuki T. The Cytoplasmic Domain of Alzheimer’s Amyloid Precursor Protein Is Phosphorylated at Thr654, Ser655, and Thr668 in Adult Rat Brain and Cultured Cells. Molecular Medicine 1997, 3: 111-123. PMID: 9085254, PMCID: PMC2230054, DOI: 10.1007/bf03401803.
• Characterization of novel calmodulin-binding peptides with distinct inhibitory effects on calmodulin-dependent enzymesNEVALAINEN L, AOYAMA T, IKURA M, CRIVICI A, Hong Y, CHUA N, NAIRN A. Characterization of novel calmodulin-binding peptides with distinct inhibitory effects on calmodulin-dependent enzymes. Biochemical Journal 1997, 321: 107-115. PMID: 9003408, PMCID: PMC1218043, DOI: 10.1042/bj3210107.
• Cardiac Myocytes Gap Junctions: Phosphorylation of CX43 through a Protein Kinase C-Dependent PathwaySáez J, Nairn A, Czernik A, Fishman G, Spray D, Hertzberg E. Cardiac Myocytes Gap Junctions: Phosphorylation of CX43 through a Protein Kinase C-Dependent Pathway. 1997, 381-394. DOI: 10.1007/978-1-4899-1795-9_22.
• Inhibition of Tumor Necrosis Factor Signal Transduction in Endothelial Cells by Dimethylaminopurine*Marino M, Dunbar J, Wu L, Ngaiza J, Han H, Guo D, Matsushita M, Nairn A, Zhang Y, Kolesnick R, Jaffe E, Donner D. Inhibition of Tumor Necrosis Factor Signal Transduction in Endothelial Cells by Dimethylaminopurine*. Journal Of Biological Chemistry 1996, 271: 28624-28629. PMID: 8910494, DOI: 10.1074/jbc.271.45.28624.
• Amyloid β Peptide Formation in Cell-free Preparations REGULATION BY PROTEIN KINASE C, CALMODULIN, AND CALCINEURIN*Desdouits F, Buxbaum J, Desdouits-Magnen J, Nairn A, Greengard P. Amyloid β Peptide Formation in Cell-free Preparations REGULATION BY PROTEIN KINASE C, CALMODULIN, AND CALCINEURIN*. Journal Of Biological Chemistry 1996, 271: 24670-24674. PMID: 8798734, DOI: 10.1074/jbc.271.40.24670.
• Developmental expression of MARCKS and protein kinase C in mice in relation to the exencephaly resulting from MARCKS deficiencyBlackshear P, Lai W, Tuttle J, Stumpo D, Kennington E, Nairn A, Sulik K. Developmental expression of MARCKS and protein kinase C in mice in relation to the exencephaly resulting from MARCKS deficiency. Brain Research 1996, 96: 62-75. PMID: 8922669, DOI: 10.1016/0165-3806(96)00097-1.
• Activation of a Calcium-Calmodulin-dependent Protein Kinase I Cascade in PC12 Cells*Aletta J, Selbert M, Nairn A, Edelman A. Activation of a Calcium-Calmodulin-dependent Protein Kinase I Cascade in PC12 Cells*. Journal Of Biological Chemistry 1996, 271: 20930-20934. PMID: 8702851, DOI: 10.1074/jbc.271.34.20930.
• cGMP-Dependent Protein Kinase in Dorsal Root Ganglion: Relationship with Nitric Oxide Synthase and Nociceptive NeuronsQian Y, Chao D, Santillano D, Cornwell T, Nairn A, Greengard P, Lincoln T, Bredt D. cGMP-Dependent Protein Kinase in Dorsal Root Ganglion: Relationship with Nitric Oxide Synthase and Nociceptive Neurons. Journal Of Neuroscience 1996, 16: 3130-3138. PMID: 8627352, PMCID: PMC6579134, DOI: 10.1523/jneurosci.16-10-03130.1996.
• Structural Basis for the Autoinhibition of Calcium/Calmodulin-Dependent Protein Kinase IGoldberg J, Nairn A, Kuriyan J. Structural Basis for the Autoinhibition of Calcium/Calmodulin-Dependent Protein Kinase I. Cell 1996, 84: 875-887. PMID: 8601311, DOI: 10.1016/s0092-8674(00)81066-1.
• Structure, Regulation, and Function of Calcium/Calmodulin-Dependent Protein Kinase IPicciotto M, Nastiuk K, Nairn A. Structure, Regulation, and Function of Calcium/Calmodulin-Dependent Protein Kinase I. 1996, 36: 251-275. PMID: 8783563, DOI: 10.1016/s1054-3589(08)60585-2.
• 387 Identification of a protein which interacts with the cytoplasmic domain of the Alzheimer amyloid protein PrecursorWatanabe T, Suzuki T, Sukegawa J, Sukegawa I, Nairn A, Greengard P. 387 Identification of a protein which interacts with the cytoplasmic domain of the Alzheimer amyloid protein Precursor. Neurobiology Of Aging 1996, 17: s97. DOI: 10.1016/s0197-4580(96)80389-7.
• Isotype-specific Activation of Cystic Fibrosis Transmembrane Conductance Regulator-Chloride Channels by cGMP-dependent Protein Kinase II (∗)French P, Bijman J, Edixhoven M, Vaandrager A, Scholte B, Lohmann S, Nairn A, de Jonge H. Isotype-specific Activation of Cystic Fibrosis Transmembrane Conductance Regulator-Chloride Channels by cGMP-dependent Protein Kinase II (∗). Journal Of Biological Chemistry 1995, 270: 26626-26631. PMID: 7592887, DOI: 10.1074/jbc.270.44.26626.
• The Regulatory Region of Calcium/Calmodulin-dependent Protein Kinase I Contains Closely Associated Autoinhibitory and Calmodulin-binding Domains (∗)Yokokura H, Picciotto M, Nairn A, Hidaka H. The Regulatory Region of Calcium/Calmodulin-dependent Protein Kinase I Contains Closely Associated Autoinhibitory and Calmodulin-binding Domains (∗). Journal Of Biological Chemistry 1995, 270: 23851-23859. PMID: 7559563, DOI: 10.1074/jbc.270.40.23851.
• Rapamycin inhibits ribosomal protein synthesis and induces G1 prolongation in mitogen-activated T lymphocytes.Terada N, Takase K, Papst P, Nairn A, Gelfand E. Rapamycin inhibits ribosomal protein synthesis and induces G1 prolongation in mitogen-activated T lymphocytes. The Journal Of Immunology 1995, 155: 3418-26. PMID: 7561036, DOI: 10.4049/jimmunol.155.7.3418.
• Three-dimensional structure of the catalytic subunit of protein serine/threonine phosphatase-1Goldberg J, Huang H, Kwon Y, Greengard P, Nairn A, Kuriyan J. Three-dimensional structure of the catalytic subunit of protein serine/threonine phosphatase-1. Nature 1995, 376: 745-753. PMID: 7651533, DOI: 10.1038/376745a0.
• A Role for Calcineurin (Protein Phosphatase-2B) in the Regulation of Glutamate ReleaseSihra T, Nairn A, Kloppenburg P, Lin Z, Pouzat C. A Role for Calcineurin (Protein Phosphatase-2B) in the Regulation of Glutamate Release. Biochemical And Biophysical Research Communications 1995, 212: 609-616. PMID: 7542882, DOI: 10.1006/bbrc.1995.2013.
• Immunochemical localization of calcium/calmodulin‐dependent protein kinase IPicciotto M, Zoli M, Bertuzzi G, Nairn A. Immunochemical localization of calcium/calmodulin‐dependent protein kinase I. Synapse 1995, 20: 75-84. PMID: 7624832, DOI: 10.1002/syn.890200111.
• Phosphorylation of DARPP-32, a Dopamine- and cAMP-regulated Phosphoprotein, by Casein Kinase I in Vitro and in Vivo *Desdouits F, Cohen D, Nairn A, Greengard P, Girault J. Phosphorylation of DARPP-32, a Dopamine- and cAMP-regulated Phosphoprotein, by Casein Kinase I in Vitro and in Vivo *. Journal Of Biological Chemistry 1995, 270: 8772-8778. PMID: 7721783, DOI: 10.1074/jbc.270.15.8772.
• Cystic Fibrosis Transmembrane Conductance Regulator Is Found Within Brain Ventricular Epithelium and Choroid PlexusHincke M, Nairn A, Staines W. Cystic Fibrosis Transmembrane Conductance Regulator Is Found Within Brain Ventricular Epithelium and Choroid Plexus. Journal Of Neurochemistry 1995, 64: 1662-1668. PMID: 7534334, DOI: 10.1046/j.1471-4159.1995.64041662.x.
• Modulation of calcium currents by a D1 dopaminergic protein kinase/phosphatase cascade in rat neostriatal neuronsSurmeier D, Bargas J, Hemmings H, Nairn A, Greengard P. Modulation of calcium currents by a D1 dopaminergic protein kinase/phosphatase cascade in rat neostriatal neurons. Neuron 1995, 14: 385-397. PMID: 7531987, DOI: 10.1016/0896-6273(95)90294-5.
• Calcium-dependent regulation of protein synthesis.Palfrey H, Nairn A. Calcium-dependent regulation of protein synthesis. 1995, 30: 191-223. PMID: 7695990, DOI: 10.1016/s1040-7952(05)80008-4.
• P3-52 IDENTIFICATION OF AUTOINHIBITORY AND CALMODULIN-RINDING DOMAINS ON CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE IYokokura H, Picciotto M, Nairn A, Hidaka H. P3-52 IDENTIFICATION OF AUTOINHIBITORY AND CALMODULIN-RINDING DOMAINS ON CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE I. Journal Of Pharmacological Sciences 1995, 67: 259. DOI: 10.1016/s0021-5198(19)47002-9.
• CaMKI CaM-dependent protein kinase I (vertebrates)Edelman A, Nairn A. CaMKI CaM-dependent protein kinase I (vertebrates). 1995, 128-130. DOI: 10.1016/b978-012324719-3/50029-7.
• EF2K Elongation factor-2 kinase (vertebrates) (CaM-dependent PK III)Nairn A. EF2K Elongation factor-2 kinase (vertebrates) (CaM-dependent PK III). 1995, 135-136. DOI: 10.1016/b978-012324719-3/50031-5.
• Rapamycin selectively inhibits translation of mRNAs encoding elongation factors and ribosomal proteins.Terada N, Patel H, Takase K, Kohno K, Nairn A, Gelfand E. Rapamycin selectively inhibits translation of mRNAs encoding elongation factors and ribosomal proteins. Proceedings Of The National Academy Of Sciences Of The United States Of America 1994, 91: 11477-11481. PMID: 7972087, PMCID: PMC45254, DOI: 10.1073/pnas.91.24.11477.
• Structure and function of calcium/calmodulin-dependent protein kinasesNairn A. Structure and function of calcium/calmodulin-dependent protein kinases. Pathophysiology 1994, 1: 73. DOI: 10.1016/0928-4680(94)90170-8.
• Regulation of CFTR channel gatingGadsby D, Nairn A. Regulation of CFTR channel gating. Trends In Biochemical Sciences 1994, 19: 513-518. PMID: 7531880, DOI: 10.1016/0968-0004(94)90141-4.
• Erratum Volume 201, Number 3 (1994), in the article "Ca2+/Calmodulin-Dependent Protein Kinase V and I May Form a Family of Isoforms," pp. 1561-1566Ito T, Yokokura H, Nairn A, Nimura Y, Hidaki H. Erratum Volume 201, Number 3 (1994), in the article "Ca2+/Calmodulin-Dependent Protein Kinase V and I May Form a Family of Isoforms," pp. 1561-1566. Biochemical And Biophysical Research Communications 1994, 203: 1935. DOI: 10.1006/bbrc.1994.2414.
• Subcellular localization of CFTR to endosomes in a ductal epitheliumWebster P, Vanacore L, Nairn A, Marino C. Subcellular localization of CFTR to endosomes in a ductal epithelium. American Journal Of Physiology 1994, 267: c340-c348. PMID: 7521124, DOI: 10.1152/ajpcell.1994.267.2.c340.
• Postsynaptic modulation of synaptic efficacy at mixed synapses on the Mauthner cellPereda A, Nairn A, Wolszon L, Faber D. Postsynaptic modulation of synaptic efficacy at mixed synapses on the Mauthner cell. Journal Of Neuroscience 1994, 14: 3704-3712. PMID: 8207483, PMCID: PMC6576949, DOI: 10.1523/jneurosci.14-06-03704.1994.
• Ca2+/Calmodulin-Dependent Protein Kinase V and I May Form a Family of IsoformsIto T, Yokokura H, Nairn A, Nimura Y, Hidaka H. Ca2+/Calmodulin-Dependent Protein Kinase V and I May Form a Family of Isoforms. Biochemical And Biophysical Research Communications 1994, 201: 1561-1566. PMID: 8024601, DOI: 10.1006/bbrc.1994.1882.
• Regulation of the gating of cystic fibrosis transmembrane conductance regulator C1 channels by phosphorylation and ATP hydrolysis.Hwang T, Nagel G, Nairn A, Gadsby D. Regulation of the gating of cystic fibrosis transmembrane conductance regulator C1 channels by phosphorylation and ATP hydrolysis. Proceedings Of The National Academy Of Sciences Of The United States Of America 1994, 91: 4698-4702. PMID: 7515176, PMCID: PMC43855, DOI: 10.1073/pnas.91.11.4698.
• Specificity of protein kinase inhibitor peptides and induction of long-term potentiation.Hvalby O, Hemmings H, Paulsen O, Czernik A, Nairn A, Godfraind J, Jensen V, Raastad M, Storm J, Andersen P. Specificity of protein kinase inhibitor peptides and induction of long-term potentiation. Proceedings Of The National Academy Of Sciences Of The United States Of America 1994, 91: 4761-4765. PMID: 8197132, PMCID: PMC43868, DOI: 10.1073/pnas.91.11.4761.
• Correlation between protein kinase C binding proteins and substrates in REF52 cells.Hyatt S, Liao L, Aderem A, Nairn A, Jaken S. Correlation between protein kinase C binding proteins and substrates in REF52 cells. Molecular Cancer Research 1994, 5: 495-502. PMID: 8049156.
• Role of elongation factor 2 in regulating peptide-chain elongation in the heartVary T, Nairn A, Lynch C. Role of elongation factor 2 in regulating peptide-chain elongation in the heart. American Journal Of Physiology 1994, 266: e628-e634. PMID: 7513958, DOI: 10.1152/ajpendo.1994.266.4.e628.
• Identification of the phosphorylation site for cAMP-dependent protein kinase on Na+,K(+)-ATPase and effects of site-directed mutagenesis.Fisone G, Cheng S, Nairn A, Czernik A, Hemmings H, Höög J, Bertorello A, Kaiser R, Bergman T, Jörnvall H. Identification of the phosphorylation site for cAMP-dependent protein kinase on Na+,K(+)-ATPase and effects of site-directed mutagenesis. Journal Of Biological Chemistry 1994, 269: 9368-9373. PMID: 7510709, DOI: 10.1016/s0021-9258(17)37117-x.
• Coupling of CFTR Cl− channel gating to an ATP hydrolysis cycleBaukrowitz T, Hwang T, Nairn A, Gadsby D. Coupling of CFTR Cl− channel gating to an ATP hydrolysis cycle. Neuron 1994, 12: 473-482. PMID: 7512348, DOI: 10.1016/0896-6273(94)90206-2.
• Regulation of CFTR channel gating.Gadsby D, Hwang T, Baukrowitz T, Nagel G, Horie M, Nairn A. Regulation of CFTR channel gating. The Journal Of Physiological Sciences 1994, 44 Suppl 2: s183-92. PMID: 7752525.
• Hormonal regulation of Na+,K+-ATPase activityAperia A, Fryckstedt J, Fisone G, Holtbäck U, Cheng S, Syrén M, Li D, Hemmings H, Nairn A, Greengard P. Hormonal regulation of Na+,K+-ATPase activity. 1994, 662-669. DOI: 10.1007/978-3-642-72511-1_120.
• Regulated phosphorylation of APP in vivoOishi M, Lim G, Isohara T, Watanabe T, Qu Z, Horiuchi A, Marshak D, Czernik A, Nairn A, Greengard P, Suzuki T. Regulated phosphorylation of APP in vivo. Neurobiology Of Aging 1994, 15: s84. DOI: 10.1016/0197-4580(94)92796-0.
• Localization of the cystic fibrosis transmembrane conductance regulator in human bile duct epithelial cellsCohn J, Strong T, Picciotto M, Nairn A, Collins F, Fitz J. Localization of the cystic fibrosis transmembrane conductance regulator in human bile duct epithelial cells. Gastroenterology 1993, 105: 1857-1864. PMID: 7504645, DOI: 10.1016/0016-5085(93)91085-v.
• Cardiac Chloride Channels: Incremental Regulation by Phosphorylation/DephosphorylationaGADSBY D, HWANG T, HORIE M, NAGEL G, NAIRN A. Cardiac Chloride Channels: Incremental Regulation by Phosphorylation/Dephosphorylationa. Annals Of The New York Academy Of Sciences 1993, 707: 259-274. PMID: 9137557, DOI: 10.1111/j.1749-6632.1993.tb38057.x.
• Protein Phosphorylation Regulates Relative Utilization of Processing Pathways for Alzheimer β/A4 Amyloid Precursor ProteinaGANDY S, CAPORASO G, BUXBAUM J, DA CRUZ E SILVA O, IVERFELDT K, NORDSTEDT C, SUZUKI T, CZERNIK A, NAIRN A, GREENGARD P. Protein Phosphorylation Regulates Relative Utilization of Processing Pathways for Alzheimer β/A4 Amyloid Precursor Proteina. Annals Of The New York Academy Of Sciences 1993, 695: 117-121. PMID: 8239268, DOI: 10.1111/j.1749-6632.1993.tb23038.x.
• Purification and characterization of calmodulin-dependent protein kinase III from rabbit reticulocytes and rat pancreasMitsui K, Brady M, Palfrey H, Nairn A. Purification and characterization of calmodulin-dependent protein kinase III from rabbit reticulocytes and rat pancreas. Journal Of Biological Chemistry 1993, 268: 13422-13433. PMID: 8514778, DOI: 10.1016/s0021-9258(19)38667-3.
• Phosphorylation of elongation factor 2 in normal and malignant rat glial cells.Bagaglio DM, Cheng EH, Gorelick FS, Mitsui K, Nairn AC, Hait WN. Phosphorylation of elongation factor 2 in normal and malignant rat glial cells. Cancer Research 1993, 53: 2260-4. PMID: 8485712.
• CHAPTER 39 Rat connexin43: regulation by phosphorylation in heartSÁEZ J, NAIRN A, CZERNIK A, SPRAY D, HERTZBERG E. CHAPTER 39 Rat connexin43: regulation by phosphorylation in heart. 1993, 275-281. DOI: 10.1016/b978-0-444-89871-5.50044-4.
• Protein Phosphorylation Regulates the Cellular Trafficking and Processing of the Alzheimer Beta/A4 Amyloid Precursor ProteinCaporaso G, Gandy S, Buxbaum J, Suzuki T, Nordstedt C, Iverfeldt K, Ramabhadran T, Czernik A, Nairn A, Greengard P. Protein Phosphorylation Regulates the Cellular Trafficking and Processing of the Alzheimer Beta/A4 Amyloid Precursor Protein. 1993, 201-202. DOI: 10.1007/978-3-662-02928-2_42.
• Characterization of Alternative Routes for Processing of the Alzheimer β/A4‐Amyloid Precursor ProteinGANDY S, CAPORASO G, RAMABHADRAN T, SUZUKI T, BUXBAUM J, NORDSTEDT C, IVERFELDT K, CZERNIK A, NAIRN A, GREENGARD P. Characterization of Alternative Routes for Processing of the Alzheimer β/A4‐Amyloid Precursor Protein. Annals Of The New York Academy Of Sciences 1992, 674: 203-217. PMID: 1363189, DOI: 10.1111/j.1749-6632.1992.tb27489.x.
• The protein kinase A-regulated cardiac CI− channel resembles the cystic fibrosis transmembrane conductance regulatorNagel G, Hwang T, Nastiuk K, Nairn A, Gadsbyt D. The protein kinase A-regulated cardiac CI− channel resembles the cystic fibrosis transmembrane conductance regulator. Nature 1992, 360: 81-84. PMID: 1279437, DOI: 10.1038/360081a0.
• Increased phosphorylation of elongation factor 2 in Alzheimer's diseaseJohnson G, Gotlib J, Haroutunian V, Bierer L, Nairn A, Merril C, Wallace W. Increased phosphorylation of elongation factor 2 in Alzheimer's disease. Brain Research 1992, 15: 319-326. PMID: 1331687, DOI: 10.1016/0169-328x(92)90124-t.
• The nature and metabolism of potentially amyloidogenic carboxyl-terminal fragments of the Alzheimer βA4-amyloid precursor protein: Some technical notesGandy S, Buxbaum J, Suzuki T, Ramabhadran T, Caporaso G, Nairn A, Greengard P. The nature and metabolism of potentially amyloidogenic carboxyl-terminal fragments of the Alzheimer βA4-amyloid precursor protein: Some technical notes. Neurobiology Of Aging 1992, 13: 601-603. PMID: 1461349, DOI: 10.1016/0197-4580(92)90063-4.
• Distribution of Protein Phosphatase Inhibitor‐1 in Brain and Peripheral Tissues of Various Species: Comparison with DARPP‐32Hemmings H, Girault J, Nairn A, Bertuzzi G, Greengard P. Distribution of Protein Phosphatase Inhibitor‐1 in Brain and Peripheral Tissues of Various Species: Comparison with DARPP‐32. Journal Of Neurochemistry 1992, 59: 1053-1061. PMID: 1353788, DOI: 10.1111/j.1471-4159.1992.tb08347.x.
• The role of protein phosphatases in synaptic transmission, plasticity and neuronal developmentNairn A, Shenolikar S. The role of protein phosphatases in synaptic transmission, plasticity and neuronal development. Current Opinion In Neurobiology 1992, 2: 296-301. PMID: 1322750, DOI: 10.1016/0959-4388(92)90118-5.
• The role of protein phosphatases in synaptic transmission, plasticity and neuronal developmentNairn A, Shenolikar S. The role of protein phosphatases in synaptic transmission, plasticity and neuronal development. Current Biology 1992, 2: 291-292. DOI: 10.1016/0960-9822(92)90866-9.
• cGMP-dependent protein kinase regulation of a chloride channel in T84 cellsLin M, Nairn A, Guggino S. cGMP-dependent protein kinase regulation of a chloride channel in T84 cells. American Journal Of Physiology 1992, 262: c1304-c1312. PMID: 1317106, DOI: 10.1152/ajpcell.1992.262.5.c1304.
• Role of GTP-binding proteins in the regulation of mammalian cardiac chloride conductance.Hwang T, Horie M, Nairn A, Gadsby D. Role of GTP-binding proteins in the regulation of mammalian cardiac chloride conductance. The Journal Of General Physiology 1992, 99: 465-489. PMID: 1375958, PMCID: PMC2219206, DOI: 10.1085/jgp.99.4.465.
• MARCKS is an actin filament crosslinking protein regulated by protein kinase C and calcium–calmodulinHartwig J, Thelen M, Resen A, Janmey P, Nairn A, Aderem A. MARCKS is an actin filament crosslinking protein regulated by protein kinase C and calcium–calmodulin. Nature 1992, 356: 618-622. PMID: 1560845, DOI: 10.1038/356618a0.
• Characterization of the cystic fibrosis transmembrane conductance regulator in a colonocyte cell line.Cohn J, Nairn A, Marino C, Melhus O, Kole J. Characterization of the cystic fibrosis transmembrane conductance regulator in a colonocyte cell line. Proceedings Of The National Academy Of Sciences Of The United States Of America 1992, 89: 2340-2344. PMID: 1372442, PMCID: PMC48653, DOI: 10.1073/pnas.89.6.2340.
• Phosphorylation of elongation factor 2 during Ca2+-mediated secretion from rat parotid aciniHincke M, Nairn A. Phosphorylation of elongation factor 2 during Ca2+-mediated secretion from rat parotid acini. Biochemical Journal 1992, 282: 877-882. PMID: 1372803, PMCID: PMC1130869, DOI: 10.1042/bj2820877.
• Mechanism of desensitization of the epidermal growth factor receptor protein-tyrosine kinase.Countaway J, Nairn A, Davis R. Mechanism of desensitization of the epidermal growth factor receptor protein-tyrosine kinase. Journal Of Biological Chemistry 1992, 267: 1129-1140. PMID: 1309762, DOI: 10.1016/s0021-9258(18)48406-2.
• Calmodulin and Protein Kinase C Cross‐Talk: The MARCKS Protein is an Actin Filament and Plasma Membrane Cross‐Linking Protein Regulated by Protein Kinase C Phosphorylation and by CalmodulinNairn A, Aderem A. Calmodulin and Protein Kinase C Cross‐Talk: The MARCKS Protein is an Actin Filament and Plasma Membrane Cross‐Linking Protein Regulated by Protein Kinase C Phosphorylation and by Calmodulin. 1992, 164: 145-161. PMID: 1395931, DOI: 10.1002/9780470514207.ch10.
• Protein Phosphorylation Regulates Processing of the Alzheimer β/A4-Amyloid Precursor ProteinGandy S, Caporaso G, Ramabhadran T, Buxbaum J, Suzuki T, Nordstedt C, Iverfeldt K, Czernik A, Nairn A, Greengard P. Protein Phosphorylation Regulates Processing of the Alzheimer β/A4-Amyloid Precursor Protein. 1992, 130-143. DOI: 10.1007/978-3-642-46776-9_14.
• Evidence for isoproterenol-induced phosphorylation of phosphatase inhibitor-1 in the intact heart.Neumann J, Gupta R, Schmitz W, Scholz H, Nairn A, Watanabe A. Evidence for isoproterenol-induced phosphorylation of phosphatase inhibitor-1 in the intact heart. Circulation Research 1991, 69: 1450-1457. PMID: 1659500, DOI: 10.1161/01.res.69.6.1450.
• Identification and localization of a dogfish homolog of human cystic fibrosis transmembrane conductance regulator.Marshall J, Martin K, Picciotto M, Hockfield S, Nairn A, Kaczmarek L. Identification and localization of a dogfish homolog of human cystic fibrosis transmembrane conductance regulator. Journal Of Biological Chemistry 1991, 266: 22749-22754. PMID: 1718999, DOI: 10.1016/s0021-9258(18)54631-7.
• Enhancement of the Glutamate Response by cAMP-Dependent Protein Kinase in Hippocampal NeuronsGreengard P, Jen J, Nairn A, Stevens C. Enhancement of the Glutamate Response by cAMP-Dependent Protein Kinase in Hippocampal Neurons. Science 1991, 253: 1135-1138. PMID: 1716001, DOI: 10.1126/science.1716001.
• Immunocytochemical localization of phosphatase inhibitor‐1 in rat brainGustafson E, Girault J, Hemmings H, Nairn A, Greengard P. Immunocytochemical localization of phosphatase inhibitor‐1 in rat brain. The Journal Of Comparative Neurology 1991, 310: 170-188. PMID: 1955581, DOI: 10.1002/cne.903100204.
• Protein kinase C substrate and inhibitor characteristics of peptides derived from the myristoylated alanine-rich C kinase substrate (MARCKS) protein phosphorylation site domainGraff J, Rajan R, Randall R, Nairn A, Blackshear P. Protein kinase C substrate and inhibitor characteristics of peptides derived from the myristoylated alanine-rich C kinase substrate (MARCKS) protein phosphorylation site domain. Journal Of Biological Chemistry 1991, 266: 14390-14398. PMID: 1650359, DOI: 10.1016/s0021-9258(18)98697-7.
• Regulation by phosphorylation of reversible association of a myristoylated protein kinase C substrate with the plasma membraneThelen M, Rosen A, Nairn A, Aderem A. Regulation by phosphorylation of reversible association of a myristoylated protein kinase C substrate with the plasma membrane. Nature 1991, 351: 320-322. PMID: 2034276, DOI: 10.1038/351320a0.
• [23] Production of phosphorylation state-specific antibodiesJczernik A, Girault J, Nairn A, Chen J, Snyder G, Kebabian J, Greengard P. [23] Production of phosphorylation state-specific antibodies. 1991, 201: 264-283. PMID: 1943769, DOI: 10.1016/0076-6879(91)01025-w.
• Protein phosphatases: recent progress.Shenolikar S, Nairn A. Protein phosphatases: recent progress. 1991, 23: 1-121. PMID: 1847640.
• P2‐Purinergic Receptors on Vascular Endothelial CellsPIROTTON S, LECOMTE M, ROBAYE B, DEMOLLE D, VAN COEVORDEN A, NAIRN A, BOEYNAEMS J. P2‐Purinergic Receptors on Vascular Endothelial Cells. Annals Of The New York Academy Of Sciences 1990, 603: 480-483. DOI: 10.1111/j.1749-6632.1990.tb37712.x.
• Activation of protein kinase C results in the displacement of its myristoylated, alanine-rich substrate from punctate structures in macrophage filopodia.Rosen A, Keenan K, Thelen M, Nairn A, Aderem A. Activation of protein kinase C results in the displacement of its myristoylated, alanine-rich substrate from punctate structures in macrophage filopodia. Journal Of Experimental Medicine 1990, 172: 1211-1215. PMID: 2212950, PMCID: PMC2188604, DOI: 10.1084/jem.172.4.1211.
• Phosphorylation of connexin 32, a hepatocyte gap‐junction protein, by cAMP‐dependent protein kinase, protein kinase C and Ca2+/calmodulin‐dependent protein kinase IISAEZ J, NAIRN A, CZERNIK A, SPRAY D, HERTZBERG E, GREENGARD P, BENNETT M. Phosphorylation of connexin 32, a hepatocyte gap‐junction protein, by cAMP‐dependent protein kinase, protein kinase C and Ca2+/calmodulin‐dependent protein kinase II. The FEBS Journal 1990, 192: 263-273. PMID: 2170122, DOI: 10.1111/j.1432-1033.1990.tb19223.x.
• Tumor necrosis factor alpha modifies agonist-dependent responses in human neutrophils by inducing the synthesis and myristoylation of a specific protein kinase C substrate.Thelen M, Rosen A, Nairn A, Aderem A. Tumor necrosis factor alpha modifies agonist-dependent responses in human neutrophils by inducing the synthesis and myristoylation of a specific protein kinase C substrate. Proceedings Of The National Academy Of Sciences Of The United States Of America 1990, 87: 5603-5607. PMID: 2116001, PMCID: PMC54375, DOI: 10.1073/pnas.87.15.5603.
• Amiloride analogs induce the phosphorylation of elongation factor-2 in vascular endothelial cells.Demolle D, Lecomte M, Boutherin-Falson O, Cragoe E, Nairn A, Boeynaems J. Amiloride analogs induce the phosphorylation of elongation factor-2 in vascular endothelial cells. Molecular Pharmacology 1990, 37: 827-32. PMID: 2359404.
• Nerve Growth Factor‐Induced Down‐Regulation of Calmodulin‐Dependent Protein Kinase III in PC12 Cells Involves Cyclic AMP‐Dependent Protein KinaseBrady M, Nairn A, Wagner J, Palfrey H. Nerve Growth Factor‐Induced Down‐Regulation of Calmodulin‐Dependent Protein Kinase III in PC12 Cells Involves Cyclic AMP‐Dependent Protein Kinase. Journal Of Neurochemistry 1990, 54: 1034-1039. PMID: 1689374, DOI: 10.1111/j.1471-4159.1990.tb02354.x.
• Calcium/calmodulin-dependent protein kinase II increases glutamate and noradrenaline release from synaptosomesNichols R, Sihra T, Czernik A, Nairn A, Greengard P. Calcium/calmodulin-dependent protein kinase II increases glutamate and noradrenaline release from synaptosomes. Nature 1990, 343: 647-651. PMID: 2154695, DOI: 10.1038/343647a0.
• Role of Ca2+/calmodulin-dependent protein phosphorylation in signal transduction.Nairn A. Role of Ca2+/calmodulin-dependent protein phosphorylation in signal transduction. 1990, 24: 202-5. PMID: 1976329.
• Multisite phosphorylation of microtubule-associated protein 2 (MAP-2) in rat brain: Peptide mapping distinguishes between cyclic AMP-, calcium/calmodulin-, and calcium/phospholipid-regulated phosphorylation mechanismsWalaas S, Nairn A. Multisite phosphorylation of microtubule-associated protein 2 (MAP-2) in rat brain: Peptide mapping distinguishes between cyclic AMP-, calcium/calmodulin-, and calcium/phospholipid-regulated phosphorylation mechanisms. Journal Of Molecular Neuroscience 1989, 1: 117-127. DOI: 10.1007/bf02918897.
• Chloride conductance regulated by cyclic AMP-dependent protein kinase in cardiac myocytesBahinski A, Nairn A, Greengard P, Gadsby D. Chloride conductance regulated by cyclic AMP-dependent protein kinase in cardiac myocytes. Nature 1989, 340: 718-721. PMID: 2475783, DOI: 10.1038/340718a0.
• Insulin rapidly induces the biosynthesis of elongation factor 2Levenson R, Nairn A, Blackshear P. Insulin rapidly induces the biosynthesis of elongation factor 2. Journal Of Biological Chemistry 1989, 264: 11904-11911. PMID: 2663845, DOI: 10.1016/s0021-9258(18)80152-1.
• Regulation of Chloride Channels by Protein Kinase C in Normal and Cystic Fibrosis Airway EpitheliaLi M, McCann J, Anderson M, Clancy J, Liedtke C, Nairn A, Greengard P, Welsch M. Regulation of Chloride Channels by Protein Kinase C in Normal and Cystic Fibrosis Airway Epithelia. Science 1989, 244: 1353-1356. PMID: 2472006, DOI: 10.1126/science.2472006.
• Identification of two protein kinases that phosphorylate the neural cell-adhesion molecule, N-CAMMackie K, Sorkin B, Nairn A, Greengard P, Edelman G, Cunningham B. Identification of two protein kinases that phosphorylate the neural cell-adhesion molecule, N-CAM. Journal Of Neuroscience 1989, 9: 1883-1896. PMID: 2542481, PMCID: PMC6569722, DOI: 10.1523/jneurosci.09-06-01883.1989.
• Multisite phosphorylation of microtubule-associated protein 2 (MAP-2) in rat brain: Peptide mapping distinguishes between cyclic AMP-, calcium/calmodulin-, and calcium/phospholipid-regulated phosphorylation mechanismsIvar Walaas S, Nairn A. Multisite phosphorylation of microtubule-associated protein 2 (MAP-2) in rat brain: Peptide mapping distinguishes between cyclic AMP-, calcium/calmodulin-, and calcium/phospholipid-regulated phosphorylation mechanisms. Journal Of Molecular Neuroscience 1989, 1: 117-127. PMID: 2561875, DOI: 10.1007/bf02896895.
• Role of protein phosphorylation in neuronal signal transduction1Hemmings H, Nairn A, McGuinness T, Huganir R, Greengard P. Role of protein phosphorylation in neuronal signal transduction1. The FASEB Journal 1989, 3: 1583-1592. PMID: 2493406, DOI: 10.1096/fasebj.3.5.2493406.
• Protein kinase inhibitors selectively block phorbol ester- or forskolin- induced changes in excitability of Aplysia neuronsConn P, Strong J, Azhderian E, Nairn A, Greengard P, Kaczmarek L. Protein kinase inhibitors selectively block phorbol ester- or forskolin- induced changes in excitability of Aplysia neurons. Journal Of Neuroscience 1989, 9: 473-479. PMID: 2537389, PMCID: PMC6569795, DOI: 10.1523/jneurosci.09-02-00473.1989.
• Thrombin and Histamine Stimulate the Phosphorylation of Elongation Factor 2 in Human Umbilical Vein Endothelial CellsMackie K, Nairn A, Hampel G, Lam G, Jaffe E. Thrombin and Histamine Stimulate the Phosphorylation of Elongation Factor 2 in Human Umbilical Vein Endothelial Cells. Journal Of Biological Chemistry 1989, 264: 1748-1753. PMID: 2536373, DOI: 10.1016/s0021-9258(18)94250-x.
• Autophosphorylation and activation of Ca2+/calmodulin-dependent protein kinase II in intact nerve terminals.Gorelick FS, Wang JK, Lai Y, Nairn AC, Greengard P. Autophosphorylation and activation of Ca2+/calmodulin-dependent protein kinase II in intact nerve terminals. Journal Of Biological Chemistry 1988, 263: 17209-17212. PMID: 2846557, DOI: 10.1016/s0021-9258(19)77816-8.
• Protein kinases 1988: a current perspectiveBlackshear P, Nairn A, Kuo J. Protein kinases 1988: a current perspective. The FASEB Journal 1988, 2: 2957-2969. PMID: 2972578, DOI: 10.1096/fasebj.2.14.2972578.
• Ca2+/calmodulin-dependent protein kinase II: identification of threonine-286 as the autophosphorylation site in the alpha subunit associated with the generation of Ca2+-independent activity.Thiel G, Czernik AJ, Gorelick F, Nairn AC, Greengard P. Ca2+/calmodulin-dependent protein kinase II: identification of threonine-286 as the autophosphorylation site in the alpha subunit associated with the generation of Ca2+-independent activity. Proceedings Of The National Academy Of Sciences Of The United States Of America 1988, 85: 6337-6341. PMID: 2842767, PMCID: PMC281965, DOI: 10.1073/pnas.85.17.6337.
• Skeletal muscle sarcolemma proteins as targets for adenosine 3′:5′-monophosphate-dependent and calcium-dependent protein kinasesWalaas S, Horn R, Nairn A, Walaas O, Adler A. Skeletal muscle sarcolemma proteins as targets for adenosine 3′:5′-monophosphate-dependent and calcium-dependent protein kinases. Archives Of Biochemistry And Biophysics 1988, 262: 245-258. PMID: 3355169, DOI: 10.1016/0003-9861(88)90186-5.
• Purification and characterization of PCPP‐260: A Purkinje cell‐enriched cyclic amp‐regulated membrane phosphoprotein of Mr 260,000Weeks G, Picciotto M, Nairn A, Walaas S, Greengard P. Purification and characterization of PCPP‐260: A Purkinje cell‐enriched cyclic amp‐regulated membrane phosphoprotein of Mr 260,000. Synapse 1988, 2: 89-96. PMID: 2844000, DOI: 10.1002/syn.890020112.
• Cyclic AMP-dependent protein kinase opens chloride channels in normal but not cystic fibrosis airway epitheliumLi M, McCann J, Liedtket C, Nairn A, Greengard P, Welsh M. Cyclic AMP-dependent protein kinase opens chloride channels in normal but not cystic fibrosis airway epithelium. Nature 1988, 331: 358-360. PMID: 2448645, DOI: 10.1038/331358a0.
• DARPP‐32 and Phosphatase Inhibitor‐1, Two Structurally Related Inhibitors of Protein Phosphatase‐1, Are Both Present in Striatonigral NeuronsNairn A, Hemmings H, Walaas S, Greengard P. DARPP‐32 and Phosphatase Inhibitor‐1, Two Structurally Related Inhibitors of Protein Phosphatase‐1, Are Both Present in Striatonigral Neurons. Journal Of Neurochemistry 1988, 50: 257-262. PMID: 3335843, DOI: 10.1111/j.1471-4159.1988.tb13258.x.
• Identification of the major Mr 100,000 substrate for calmodulin-dependent protein kinase III in mammalian cells as elongation factor-2.Nairn A, Palfrey H. Identification of the major Mr 100,000 substrate for calmodulin-dependent protein kinase III in mammalian cells as elongation factor-2. Journal Of Biological Chemistry 1987, 262: 17299-17303. PMID: 3693353, DOI: 10.1016/s0021-9258(18)45377-x.
• Nerve growth factor treatment or cAMP elevation reduces Ca2+/calmodulin-dependent protein kinase III activity in PC12 cells.Nairn A, Nichols R, Brady M, Palfrey H. Nerve growth factor treatment or cAMP elevation reduces Ca2+/calmodulin-dependent protein kinase III activity in PC12 cells. Journal Of Biological Chemistry 1987, 262: 14265-14272. PMID: 2443502, DOI: 10.1016/s0021-9258(18)47933-1.
• Ca2+/calmodulin-dependent protein kinase II: identification of autophosphorylation sites responsible for generation of Ca2+/calmodulin-independence.Lai Y, Nairn AC, Gorelick F, Greengard P. Ca2+/calmodulin-dependent protein kinase II: identification of autophosphorylation sites responsible for generation of Ca2+/calmodulin-independence. Proceedings Of The National Academy Of Sciences Of The United States Of America 1987, 84: 5710-5714. PMID: 3475699, PMCID: PMC298932, DOI: 10.1073/pnas.84.16.5710.
• Rapid activation of calmodulin-dependent protein kinase III in mitogen-stimulated human fibroblasts. Correlation with intracellular Ca2+ transients.Palfrey H, Nairn A, Muldoon L, Villereal M. Rapid activation of calmodulin-dependent protein kinase III in mitogen-stimulated human fibroblasts. Correlation with intracellular Ca2+ transients. Journal Of Biological Chemistry 1987, 262: 9785-9792. PMID: 3496338, DOI: 10.1016/s0021-9258(18)48002-7.
• The cyclic nucleotide-dependent phosphorylation of aortic smooth muscle membrane proteinsParks T, Nairn A, Greengard P, Jamieson J. The cyclic nucleotide-dependent phosphorylation of aortic smooth muscle membrane proteins. Archives Of Biochemistry And Biophysics 1987, 255: 361-371. PMID: 3036005, DOI: 10.1016/0003-9861(87)90404-8.
• Cholecystokinin induces a decrease in Ca2+ current in snail neurons that appears to be mediated by protein kinase CHammond C, Paupardin-Tritsch D, Nairn A, Greengard P, Gerschenfeld H. Cholecystokinin induces a decrease in Ca2+ current in snail neurons that appears to be mediated by protein kinase C. Nature 1987, 325: 809-811. PMID: 2434859, DOI: 10.1038/325809a0.
• cGMP-dependent protein kinase enhances Ca2+ current and potentiates the serotonin-induced Ca2+ current increase in snail neuronesPaupardin-Tritsch D, Hammond C, Gerschenfeld H, Nairn A, Greengard P. cGMP-dependent protein kinase enhances Ca2+ current and potentiates the serotonin-induced Ca2+ current increase in snail neurones. Nature 1986, 323: 812-814. PMID: 3022154, DOI: 10.1038/323812a0.
• Intracellular injection of cGMP-dependent protein kinase results in increased input resistance in neurons of the mammalian motor cortexWoody C, Bartfai T, Gruen E, Nairn A. Intracellular injection of cGMP-dependent protein kinase results in increased input resistance in neurons of the mammalian motor cortex. Brain Research 1986, 386: 379-385. PMID: 3779415, DOI: 10.1016/0006-8993(86)90175-7.
• Protein phosphorylation in cultured endothelial cellsMackie K, Lai Y, Nairn A, Greengard P, Pitt B, Lazo J. Protein phosphorylation in cultured endothelial cells. Journal Of Cellular Physiology 1986, 128: 367-374. PMID: 3745280, DOI: 10.1002/jcp.1041280304.
• Identification of calmodulin-dependent protein kinase III and its major Mr 100,000 substrate in mammalian tissues.Nairn A, Bhagat B, Palfrey H. Identification of calmodulin-dependent protein kinase III and its major Mr 100,000 substrate in mammalian tissues. Proceedings Of The National Academy Of Sciences Of The United States Of America 1985, 82: 7939-7943. PMID: 3906654, PMCID: PMC390885, DOI: 10.1073/pnas.82.23.7939.
• Calcium-Regulated Protein Phosphorylation in Mammalian BrainWalaas S, Nairn A. Calcium-Regulated Protein Phosphorylation in Mammalian Brain. 1985, 238-264. DOI: 10.1007/978-3-642-70070-5_12.
• The amino acid sequence of rabbit skeletal muscle calmodulinNairn A, Grand R, Perry S. The amino acid sequence of rabbit skeletal muscle calmodulin. FEBS Letters 1984, 167: 215-220. PMID: 6698209, DOI: 10.1016/0014-5793(84)80129-5.
• Cyclic Nucleotide‐Dependent Protein Kinases and Some Major Substrates in the Rat Cerebellum After Neonatal X‐IrradiationDolphin A, Detre J, Schlichter D, Nairn A, Yeh H, Woodward D, Greengard P. Cyclic Nucleotide‐Dependent Protein Kinases and Some Major Substrates in the Rat Cerebellum After Neonatal X‐Irradiation. Journal Of Neurochemistry 1983, 40: 577-581. PMID: 6296321, DOI: 10.1111/j.1471-4159.1983.tb11321.x.
• Serum antibodies that distinguish between the phospho- and dephospho-forms of a phosphoproteinNairn A, Detre J, Casnellie J, Greengard P. Serum antibodies that distinguish between the phospho- and dephospho-forms of a phosphoprotein. Nature 1982, 299: 734-736. PMID: 6289133, DOI: 10.1038/299734a0.
• THE RELATIONSHIP OF THE STRUCTURE TO THE FUNCTION OF CALMODULIN IN THE MYOSIN LIGHT CHAIN KINASE SYSTEMNairn A, Grand R, Wall C, Perry S. THE RELATIONSHIP OF THE STRUCTURE TO THE FUNCTION OF CALMODULIN IN THE MYOSIN LIGHT CHAIN KINASE SYSTEM. Annals Of The New York Academy Of Sciences 1980, 356: 413-414. PMID: 6940506, DOI: 10.1111/j.1749-6632.1980.tb29653.x.
• The preparation of calmodulins from barley (Hordeum sp.) and basidiomycete fungiGrand R, Nairn A, Perry S. The preparation of calmodulins from barley (Hordeum sp.) and basidiomycete fungi. Biochemical Journal 1980, 185: 755-760. PMID: 6248033, PMCID: PMC1161454, DOI: 10.1042/bj1850755.
• The role of calmodulin in the myosin light-chain kinase system [proceedings].NAIRN A, PERRY S. The role of calmodulin in the myosin light-chain kinase system [proceedings]. Biochemical Society Transactions 1979, 7: 966-7. PMID: 229046, DOI: 10.1042/bst0070966.
• The Role of Calmodulin in the Structure and Regulation of Phosphorylase Kinase from Rabbit Skeletal MuscleSHENOLIKAR S, COHEN P, COHEN P, NAIRN A, PERRY S. The Role of Calmodulin in the Structure and Regulation of Phosphorylase Kinase from Rabbit Skeletal Muscle. The FEBS Journal 1979, 100: 329-337. PMID: 159817, DOI: 10.1111/j.1432-1033.1979.tb04175.x.
• Calcium-binding proteins and the regulation of contractile activity.PERRY S, GRAND R, NAIRN A, VANAMAN T, WALL C. Calcium-binding proteins and the regulation of contractile activity. Biochemical Society Transactions 1979, 7: 619-22. PMID: 383543, DOI: 10.1042/bst0070619.
• Calmodulin and myosin light-chain kinase of rabbit fast skeletal muscleNairn A, Perry S. Calmodulin and myosin light-chain kinase of rabbit fast skeletal muscle. Biochemical Journal 1979, 179: 89-97. PMID: 224861, PMCID: PMC1186598, DOI: 10.1042/bj1790089.
• PHOSPHORYLATION OF THE MYOFIBRILLAR PROTEINSPerry S, Cole H, Frearson N, Moir A, Nairn A, Solaro R. PHOSPHORYLATION OF THE MYOFIBRILLAR PROTEINS. 1979, 147-159. DOI: 10.1016/b978-0-08-023178-5.50018-5.
• The equilibrium constant and the reversibility of the reaction catalysed by nicotinamide-adenine dinucleotide kinase from pigeon liverApps D, Nairn A. The equilibrium constant and the reversibility of the reaction catalysed by nicotinamide-adenine dinucleotide kinase from pigeon liver. Biochemical Journal 1977, 167: 87-93. PMID: 201249, PMCID: PMC1183625, DOI: 10.1042/bj1670087.