1996
Human neuroblastoma cell lines regain catecholamine fluorescence when xenografted into athymic (nude) mice
Tomayko M, Triche T, Reynolds C. Human neuroblastoma cell lines regain catecholamine fluorescence when xenografted into athymic (nude) mice. International Journal Of Developmental Neuroscience 1996, 14: 771-777. PMID: 8960984, DOI: 10.1016/s0736-5748(96)00050-0.Peer-Reviewed Original ResearchConceptsNeuroblastoma cell linesPrimitive neuroectodermal tumorHuman neuroblastoma cell lineCatecholamine fluorescenceDense core granulesCatecholamine productionXenograft tumorsAthymic miceCell linesGlyoxylic acid-induced catecholamine fluorescenceHistochemical evidenceCore granulesNude mice tumor tissuesUseful tumor markerHuman neuroblastoma cellsMouse tumor tissuesNeuroblastoma patientsNeuroectodermal tumorUrinary catecholaminesTumor markersCatecholamine synthesisCorresponding tumorsHuman neuronsTumor tissueTumors
1993
Human neuroblastoma cell lines that express N‐myc without gene amplification
Wada R, Seeger R, Brodeur G, Einhorn P, Rayner S, Tomayko M, Reynolds C. Human neuroblastoma cell lines that express N‐myc without gene amplification. Cancer 1993, 72: 3346-3354. PMID: 8242562, DOI: 10.1002/1097-0142(19931201)72:11<3346::aid-cncr2820721134>3.0.co;2-e.Peer-Reviewed Original ResearchMeSH KeywordsAntigens, NeoplasmAntigens, SurfaceBiomarkers, TumorCatecholaminesCell DivisionChild, PreschoolGene AmplificationGene Expression Regulation, NeoplasticGenes, mycHumansKaryotypingMaleNeuritesNeuroblastomaProto-Oncogene Proteins c-mycTime FactorsTranscriptional ActivationTumor Cells, CulturedConceptsGenomic amplificationN-myc expressionCell linesN-mycNeuroblastoma cell linesUnique genetic rearrangementDouble minute chromosomesGene activationChromosome 2New cell lineGenetic rearrangementsChromosomal deletionsHuman neuroblastoma cell lineBone marrow metastasesStage IV neuroblastomaCell surface antigen expressionN-myc amplificationAggressive tumor behaviorGene amplificationSurface antigen expressionCytogenetic analysisN-myc RNAProgressive diseaseBiological basisMarrow metastases