Research Specialties

2026

Systemic lupus erythematosus-associated neutrophilic dermatoses
Saeed S, Zhou A, Gehlhausen J, Ko C, Koumpouras F, Nelson C, Ramachandran S. Systemic lupus erythematosus-associated neutrophilic dermatoses. JAAD Case Reports 2026, 68: 43-47. DOI: 10.1016/j.jdcr.2025.10.063.
Peer-Reviewed Original Research

2025

Lipophilic Statins Deplete GPX4 to Promote Ferroptosis and Sensitize Cancer Cells to Immune Checkpoint Blockade.
Talty R, Brooks V, McGeary M, Milette S, Zheng S, Flem-Karlsen K, Daniels A, Deshmukh M, Park K, Caraccio W, Yan H, Echeandia-Francis C, McNamara M, Hong S, Kirwin D, Olino K, Johnson C, Bosenberg M, Micevic G, Roy S. Lipophilic Statins Deplete GPX4 to Promote Ferroptosis and Sensitize Cancer Cells to Immune Checkpoint Blockade. Molecular Cancer Therapeutics 2025, of1-of12. PMID: 41423587, PMCID: PMC12752129, DOI: 10.1158/1535-7163.mct-25-0667.
Peer-Reviewed Original Research
Concepts
Keratinocytes as active regulators of cutaneous and mucosal immunity: a systematic review across inflammatory epithelial disorders
Klimitz F, Shen Y, Repetto F, Brown S, Knoedler L, Ko C, Abu Hussein N, Crisler W, Adams T, Kaminski N, Lian C, Murphy G, Hsia H, Pomahac B, Kauke-Navarro M. Keratinocytes as active regulators of cutaneous and mucosal immunity: a systematic review across inflammatory epithelial disorders. Frontiers In Immunology 2025, 16: 1694066. DOI: 10.3389/fimmu.2025.1694066.
Peer-Reviewed Original Research
Concepts
Acquired perforating dermatosis and nephrogenic systemic fibrosis, the importance of framing and search satisficing
Debenham L, Gehlhausen J, Ko C. Acquired perforating dermatosis and nephrogenic systemic fibrosis, the importance of framing and search satisficing. Journal Of The American Academy Of Dermatology 2025 PMID: 41390128, DOI: 10.1016/j.jaad.2025.12.028.
Peer-Reviewed Original Research
Concepts
Epithelioid Fibrous Histiocytoma With Abundant Multinucleated Giant Cells: Report of 3 Cases of an Unusual Variant With Predilection for Acral Sites
Wang S, Zubek A, Panse G. Epithelioid Fibrous Histiocytoma With Abundant Multinucleated Giant Cells: Report of 3 Cases of an Unusual Variant With Predilection for Acral Sites. American Journal Of Dermatopathology 2025, 47: 909-916. PMID: 41263920, DOI: 10.1097/dad.0000000000002937.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
Nephrogenic Systemic Fibrosis in Patients with Advanced Renal Dysfunction Following Gadolinium-based Contrast Agents.
Mallepally A, Kidd J, Grizzard J, Syed H, Chetla N, Carucci L, Cowper S, Trankle C. Nephrogenic Systemic Fibrosis in Patients with Advanced Renal Dysfunction Following Gadolinium-based Contrast Agents. Radiology 2025, 317: e251794. PMID: 41400469, PMCID: PMC12710783, DOI: 10.1148/radiol.251794.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
Dermal Hypersensitivity Reaction Masquerading as Cellulitis: An Underrecognized Diagnostic Pitfall in the Inpatient Setting
Valido K, Hong S, Damsky W, Nelson C. Dermal Hypersensitivity Reaction Masquerading as Cellulitis: An Underrecognized Diagnostic Pitfall in the Inpatient Setting. International Journal Of Dermatology 2025 PMID: 41266937, DOI: 10.1111/ijd.70169.
Peer-Reviewed Original Research
Concepts
Partial Spiky Acantholysis due to Loss of Desmosomal Attachments in Erythrokeratodermia Cardiomyopathy Syndrome
Ko C, MacGibeny M, Choate K. Partial Spiky Acantholysis due to Loss of Desmosomal Attachments in Erythrokeratodermia Cardiomyopathy Syndrome. Journal Of Cutaneous Pathology 2025 PMID: 41255294, DOI: 10.1111/cup.70016.
Peer-Reviewed Original Research
Concepts
Cutaneous Extracavitary Primary Effusion Lymphoma: A Case Report and Review of Literature
Dileep A, Zaki T, Leasure A, Xu M, Nelson C, Panse G. Cutaneous Extracavitary Primary Effusion Lymphoma: A Case Report and Review of Literature. Journal Of Cutaneous Pathology 2025 PMID: 41218762, DOI: 10.1111/cup.70007.
Peer-Reviewed Original Research
Concepts
Granuloma Annulare Patients Treated with JAK Inhibitors Show Cutibacterium acnes Expansion: A clue to the Mechanism Underlying Acneiform Eruptions Seen with JAK Inhibitors
Wang Y, Hernandez E, Junejo M, Damsky W. Granuloma Annulare Patients Treated with JAK Inhibitors Show Cutibacterium acnes Expansion: A clue to the Mechanism Underlying Acneiform Eruptions Seen with JAK Inhibitors. Journal Of Investigative Dermatology 2025 PMID: 41203008, DOI: 10.1016/j.jid.2025.10.600.
Peer-Reviewed Original Research
Concepts
1266 Spatial profiling of melanoma brain metastases exhibit elevated neural cell adhesion molecule 1 (NCAM1) protein expression and associations with immune microenvironment and treatment response
Su D, Gaiger N, Schoenfeld D, Dong M, Djureinovic D, Galan A, Chiang V, Adeniran A, Olino K, Jilaveanu L, Kluger H. 1266 Spatial profiling of melanoma brain metastases exhibit elevated neural cell adhesion molecule 1 (NCAM1) protein expression and associations with immune microenvironment and treatment response. 2025, a1441-a1443. DOI: 10.1136/jitc-2025-sitc2025.1266.
Peer-Reviewed Original Research
Concepts
171 From tissue to test: an RNA-first workflow for in situ target validation and point-of-care diagnostics
Prohroff J, Randy Chen C, Earl C, Acharya A, Choi H, Damsky W, Cohen J. 171 From tissue to test: an RNA-first workflow for in situ target validation and point-of-care diagnostics. 2025, a187-a187. DOI: 10.1136/jitc-2025-sitc2025.0171.
Peer-Reviewed Original Research
Concepts
167 Single-cell RNA sequencing nominates LAG3 as a potential therapeutic target for alopecia areata
Sanchez E, Wang Y, Kalil L, Peterson D, Hwang E, Yu W, Micevic G, Park K, King B, Damsky W. 167 Single-cell RNA sequencing nominates LAG3 as a potential therapeutic target for alopecia areata. Journal Of Investigative Dermatology 2025, 145: e58. DOI: 10.1016/j.jid.2025.09.182.
Peer-Reviewed Original Research
316 Cytokine Profiling of Monogenic Epidermal Differentiation Disorders
Mortlock R, Zhao M, Luo A, Echeandia-Francis C, Rabbaa L, Sun D, Chen T, Jiang X, Liu W, Junejo M, Cohen J, Damsky W, Paller A, Choate K. 316 Cytokine Profiling of Monogenic Epidermal Differentiation Disorders. Journal Of Investigative Dermatology 2025, 145: e81. DOI: 10.1016/j.jid.2025.09.318.
Peer-Reviewed Original Research
325 Spatial Transcriptomics Reveals Immune Cell Subsets and Tumor-Specific Keratinocytes Associated with Premalignant Lesions in Vulvar Lichen Sclerosus
Suresh A, Abi-Raad R, Panse G, Little A. 325 Spatial Transcriptomics Reveals Immune Cell Subsets and Tumor-Specific Keratinocytes Associated with Premalignant Lesions in Vulvar Lichen Sclerosus. Journal Of Investigative Dermatology 2025, 145: e82. DOI: 10.1016/j.jid.2025.09.327.
Peer-Reviewed Original Research
Concepts
Isolated perineal plaque as the initial presentation of pemphigus vulgaris
Workineh A, Panse G, Tomayko M, Little A. Isolated perineal plaque as the initial presentation of pemphigus vulgaris. JAAD Case Reports 2025, 67: 158-161. PMID: 41446696, PMCID: PMC12723278, DOI: 10.1016/j.jdcr.2025.10.034.
Peer-Reviewed Original Research
Dermatopathology Learning Needs Identified Through Continuing Certification Program Assessments of the American Board of Dermatology
Stratman E, Schaffer J, Miller S, Ferringer T, Hick R, Ko C, Roenigk R. Dermatopathology Learning Needs Identified Through Continuing Certification Program Assessments of the American Board of Dermatology. Journal Of Cutaneous Pathology 2025 PMID: 41137500, DOI: 10.1111/cup.70003.
Peer-Reviewed Original Research
Concepts
Tumor miRNA Signatures Associate with Outcomes of Patients with Stage II/III Melanoma.
Wiggins J, Zhang Q, Zhang Y, Vand-Rajabpour F, Hanniford D, He L, Lu Y, Kenney J, Sadeghi K, Argibay D, Orlow I, Busam K, Lezcano C, Lee T, Luo L, Gorlov I, Amos C, Ernstoff M, Seshan V, Cust A, Wilmott J, Scolyer R, Mann G, Reiner A, Kostrzewa C, Nagore E, Funchain P, Ko J, Edmiston S, Conway K, Googe P, Ollila D, Lee J, Rees J, Thompson C, Gerstenblith M, Bosenberg M, Gould Rothberg B, Osman I, Saenger Y, Reynolds A, Boyce T, Holmen S, Yan S, Brunsgaard E, Bogner P, Kuan P, Thomas N, Begg C, Shen R, Berwick M, Shao Y, Polsky D, Hernando E. Tumor miRNA Signatures Associate with Outcomes of Patients with Stage II/III Melanoma. Clinical Cancer Research 2025, 31: 5225-5236. PMID: 41114662, PMCID: PMC12588674, DOI: 10.1158/1078-0432.ccr-24-3785.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
The role of TCF-1+CD8+ exhausted progenitors and TCF-1 in graft-versus-host responses
Quann K, Sacirbegovic F, Rosenberger S, McFerran E, Codispot K, Garcia-Dieguez L, Rowe A, Wei W, Jain D, McNiff J, Shlomchik W. The role of TCF-1+CD8+ exhausted progenitors and TCF-1 in graft-versus-host responses. JCI Insight 2025, 10: e181568. PMID: 41059570, PMCID: PMC12507345, DOI: 10.1172/jci.insight.181568.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
Targeting an essential viral oncoprotein with an IL-7-enhanced mRNA vaccine induces durable immunity to Merkel cell carcinoma
Frey A, Clulo K, Fei Y, Dumit T, Scallo F, Allen J, Chang E, Perry C, Wirth L, Jacobs D, Braun D, Bosenberg M, Tran T, Clune J, Kluger H, Olino K, Ishizuka J. Targeting an essential viral oncoprotein with an IL-7-enhanced mRNA vaccine induces durable immunity to Merkel cell carcinoma. Cell Reports 2025, 44: 116359. PMID: 41042672, PMCID: PMC12646823, DOI: 10.1016/j.celrep.2025.116359.
Peer-Reviewed Original Research
Concepts
Reactive granulomatous dermatitis arising in the setting of interleukin-17 inhibition successfully treated with tofacitinib
Spaulding S, Wride A, Murphy M, Junejo M, Damsky W. Reactive granulomatous dermatitis arising in the setting of interleukin-17 inhibition successfully treated with tofacitinib. JAAD Case Reports 2025 DOI: 10.1016/j.jdcr.2025.09.043.
Peer-Reviewed Original Research
Concepts
Dermatologist prescribing patterns for androgenetic alopecia therapies among Medicare beneficiaries
Sun Q, Damsky W, Cohen J. Dermatologist prescribing patterns for androgenetic alopecia therapies among Medicare beneficiaries. Archives Of Dermatological Research 2025, 317: 872. DOI: 10.1007/s00403-025-04374-w.
Peer-Reviewed Original Research
Cytotoxic CD8+ T Cells Downregulate GPX4 to Promote Ferroptosis in Melanoma That Drives Antitumor Immunity.
Flem-Karlsen K, Talty R, McGeary M, Park K, Thakral D, Brooks V, Daniels A, Damsky W, Roy S, Micevic G, Bosenberg M. Cytotoxic CD8+ T Cells Downregulate GPX4 to Promote Ferroptosis in Melanoma That Drives Antitumor Immunity. Cancer Research 2025, 85: 4139-4150. PMID: 40828991, DOI: 10.1158/0008-5472.can-24-1952.
Peer-Reviewed Original Research
Concepts
0571 Linear epidermal nevus caused by a novel mosaic heterozygous PTPN11 variant
Jiang X, Chen T, Hu R, Mortlock R, Ko C, Choate K. 0571 Linear epidermal nevus caused by a novel mosaic heterozygous PTPN11 variant. Journal Of Investigative Dermatology 2025, 145: s99. DOI: 10.1016/j.jid.2025.06.578.
Peer-Reviewed Original Research
0582 Dissecting the role of inflammation in the pathogenesis of ichthyosis with confetti
Mortlock R, Yanez D, Zhou J, Little A, Damsky W, Choate K. 0582 Dissecting the role of inflammation in the pathogenesis of ichthyosis with confetti. Journal Of Investigative Dermatology 2025, 145: s101. DOI: 10.1016/j.jid.2025.06.589.
Peer-Reviewed Original Research

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