Publications

2025

Linker histone regulates the myeloid versus lymphoid bifurcation of multipotent hematopoietic stem and progenitors
Karatepe K, de Faria B, Zhang J, Chen X, Pinto H, Fyodorov D, Sefik E, Willcockson M, Flavell R, Skoultchi A, Guo S. Linker histone regulates the myeloid versus lymphoid bifurcation of multipotent hematopoietic stem and progenitors. Proceedings Of The National Academy Of Sciences Of The United States Of America 2025, 122: e2509412122. PMID: 41118213, PMCID: PMC12582276, DOI: 10.1073/pnas.2509412122.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
Successful Treatment of Alopecia Areata With One JAK Inhibitor After Failure of Other JAK Inhibitors.
Kalil L, Craiglow BG, King B. Successful Treatment of Alopecia Areata With One JAK Inhibitor After Failure of Other JAK Inhibitors. JAMA Dermatol 2025 PMID: 41060634, DOI: 10.1001/jamadermatol.2025.3537.
Peer-Reviewed Original Research
Discontinuation and restart of Janus kinase inhibitors due to pregnancy in alopecia areata: a case series
Ogbutor C, Chen L, Kalil L, Kelley K, Craiglow B, King B, Senna M. Discontinuation and restart of Janus kinase inhibitors due to pregnancy in alopecia areata: a case series. International Journal Of Women's Dermatology 2025, 11: e218. PMID: 40810112, PMCID: PMC12348381, DOI: 10.1097/jw9.0000000000000218.
Peer-Reviewed Original Research
Concepts
Targeting an essential viral oncoprotein with an IL-7-enhanced mRNA vaccine induces durable immunity to Merkel cell carcinoma
Frey A, Clulo K, Fei Y, Dumit T, Scallo F, Williams J, Chang E, Perry C, Wirth L, Jacobs D, Braun D, Bosenberg M, Tran T, Clune J, Kluger H, Olino K, Ishizuka J. Targeting an essential viral oncoprotein with an IL-7-enhanced mRNA vaccine induces durable immunity to Merkel cell carcinoma. Cell Reports 2025, 44: 116359. PMID: 41042672, DOI: 10.1016/j.celrep.2025.116359.
Peer-Reviewed Original Research
Concepts
Clinicopathological Challenge: Fixed Urticaria‐Like Pink Papules in a Patient With Recurrent Fevers and Arthralgias
Williams M, Turner N, Mendez L, Leventhal J. Clinicopathological Challenge: Fixed Urticaria‐Like Pink Papules in a Patient With Recurrent Fevers and Arthralgias. International Journal Of Dermatology 2025 PMID: 40973999, DOI: 10.1111/ijd.70083.
Peer-Reviewed Original Research
Concepts
Regional and Insurance-Based Differences in Biologic Initiation for Psoriasis Among Medicare and Commercially Insured Individuals in the United States: A Merative Marketscan Analysis
Sun Q, Cohen J. Regional and Insurance-Based Differences in Biologic Initiation for Psoriasis Among Medicare and Commercially Insured Individuals in the United States: A Merative Marketscan Analysis. Journal Of The American Academy Of Dermatology 2025 PMID: 40976535, DOI: 10.1016/j.jaad.2025.09.049.
Peer-Reviewed Original Research
Concepts
Weekly dosing schedule of brentuximab vedotin is well tolerated in mycosis fungoides/Sézary syndrome
Lee M, Schiffer M, Isufi I, Huntington S, Xu M, Sethi T, Kothari S, Girardi M, Foss F. Weekly dosing schedule of brentuximab vedotin is well tolerated in mycosis fungoides/Sézary syndrome. British Journal Of Haematology 2025 PMID: 40968584, DOI: 10.1111/bjh.70147.
Peer-Reviewed Original Research
Concepts
Sclerotic GVHD and Scleroderma Share Dysregulated Gene Expression that is Ameliorated by EREG Therapeutic Antibody
Newton N, Agrawal K, Odell A, Tracy T, Hackett C, Eldrup A, Whitfield M, Martyanov V, Girardi M, Sefik E, Flavell R, Odell I. Sclerotic GVHD and Scleroderma Share Dysregulated Gene Expression that is Ameliorated by EREG Therapeutic Antibody. Blood 2025 PMID: 40961242, DOI: 10.1182/blood.2025029836.
Peer-Reviewed Original Research
Concepts
Dermatologist prescribing patterns for androgenetic alopecia therapies among Medicare beneficiaries
Sun Q, Damsky W, Cohen J. Dermatologist prescribing patterns for androgenetic alopecia therapies among Medicare beneficiaries. Archives Of Dermatological Research 2025, 317: 872. DOI: 10.1007/s00403-025-04374-w.
Peer-Reviewed Original Research
Humanization of CD47 enables development of functional human neutrophils via postirradiation remodeling of the bone marrow.
Sefik E, Philbrick W, Zhang F, Agrawal K, Van Lee B, Sam J, Karatepe K, Zheng Y, Liang K, Peng S, Mirza H, Rangavajhula A, Simon P, Arun N, Babu P, Eynon E, Chiorazzi M, Shan L, Halene S, Luo H, Rongvaux A, Kluger Y, Flavell R. Humanization of CD47 enables development of functional human neutrophils via postirradiation remodeling of the bone marrow. Proceedings Of The National Academy Of Sciences Of The United States Of America 2025, 122: e2426546122. PMID: 40956886, PMCID: PMC12478129, DOI: 10.1073/pnas.2426546122.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
Treatment of Melasma Using Low-Fluence QS Nd: YAG (1064 nm) Laser: A Blind, Randomized, Placebo-Controlled Trial.
Sadeghpour M, Laughter M, Rizzo S, Depina J, Petrell K, Arndt K, Dover J. Treatment of Melasma Using Low-Fluence QS Nd: YAG (1064 nm) Laser: A Blind, Randomized, Placebo-Controlled Trial. Dermatologic Surgery 2025 PMID: 40932145, DOI: 10.1097/dss.0000000000004846.
Peer-Reviewed Original Research
Concepts
Cisplatin‐ineligible patients with muscle‐invasive bladder cancer demonstrate poor long‐term survival following immediate radical cystectomy
Fazili A, Jazayeri S, Rose K, Guske C, Wen L, Durant A, Prunty M, Bukavina L, Tyson M, Grass G, Xu H, Spiess P, Gilbert S, Sexton W, Zemp L, Pessoa R, Poch M, Lerner S, Li R. Cisplatin‐ineligible patients with muscle‐invasive bladder cancer demonstrate poor long‐term survival following immediate radical cystectomy. BJU International 2025 PMID: 40932312, DOI: 10.1111/bju.16895.
Peer-Reviewed Original Research
Concepts
End Points for the Next-Generation Bladder-Sparing Perioperative Trials for Patients With Muscle-Invasive Bladder Cancer.
Necchi A, Galsky M, Dizman N, Aggen D, Agarwal N, Al-Ahmadie H, Apolo A, Ballas L, Bangs R, Black P, Brausi M, Brembilla G, Cheng L, Chiti A, Cimadamore A, Colecchia M, Daneshmand S, Di Stasi S, Efstathiou J, Filicevas A, Geynisman D, Grivas P, Gupta S, Iasonos A, James N, Lerner S, Loriot Y, Makaroff L, Maluf F, Moschini M, Ostrovnaya I, Pal S, Plimack E, Prakash G, Psutka S, Rosenberg J, Sadeghi S, Schmidt B, Schwartz L, Sonpavde G, St Laurent M, Ye D, Spiess P, Kamat A. End Points for the Next-Generation Bladder-Sparing Perioperative Trials for Patients With Muscle-Invasive Bladder Cancer. Journal Of Clinical Oncology 2025, jco2501608. PMID: 40934451, PMCID: PMC12431632, DOI: 10.1200/jco-25-01608.
Peer-Reviewed Original Research
Concepts
Establishing Consensus on Defining Failure of Topical Therapy in Psoriasis: Recommendations from the International Psoriasis Council
Strober B, Blauvelt A, van de Kerkhof P, Asawanonda P, Chandra R, Gonzalez-Cantero A, Gonzalez C, Matlock B, Maul J, Rob F, Torres T, Skov L. Establishing Consensus on Defining Failure of Topical Therapy in Psoriasis: Recommendations from the International Psoriasis Council. Journal Of The American Academy Of Dermatology 2025 PMID: 40945737, DOI: 10.1016/j.jaad.2025.08.116.
Peer-Reviewed Original Research
Concepts
Factors that increase class I MHC expression may contribute to the development of immune checkpoint inhibitor-induced diabetes
Aizenbud L, Gaiger N, Perdigoto A, Mann J, Torres M, Boland G, Lawless A, Silverman S, Schoenfeld D, Destina J, Hasson N, Tran T, Hurwitz M, Austin M, Sullivan R, Herold K, Kluger H. Factors that increase class I MHC expression may contribute to the development of immune checkpoint inhibitor-induced diabetes. Journal For ImmunoTherapy Of Cancer 2025, 13: e012358. PMID: 40935567, DOI: 10.1136/jitc-2025-012358.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
Low-grade non-muscle-invasive bladder cancer: molecular landscape, treatment strategies and emerging therapies
Wen L, Miyagi H, Spiess P, Yu A, Mendelsohn C, Tan W, Psutka S, Lerner S, Cheng L, Dyrskjøt L, Meeks J, Shariat S, Gontero P, Pradere B, Steinberg G, Kamat A, Li R. Low-grade non-muscle-invasive bladder cancer: molecular landscape, treatment strategies and emerging therapies. Nature Reviews Urology 2025, 1-16. PMID: 40931081, DOI: 10.1038/s41585-025-01072-0.
Peer-Reviewed Original Research
Concepts
NivobotulinumtoxinA in the Treatment of Lateral Canthal Lines Alone and With Concurrent Treatment of Glabellar Lines.
Carruthers J, DuBois J, Friedmann D, LaTowsky B, Palm M, Rivers J, Weinkle S, Duggan S, Enfield K, Donofrio L. NivobotulinumtoxinA in the Treatment of Lateral Canthal Lines Alone and With Concurrent Treatment of Glabellar Lines. Dermatologic Surgery 2025 PMID: 40923599, DOI: 10.1097/dss.0000000000004829.
Peer-Reviewed Original Research
Concepts
Gammopathic dermopathies: A retrospective review of cutaneous response to haematologic therapy
Williams M, Bhullar S, Olamiju B, Tattersall I, Turner N, Heald P, Leventhal J. Gammopathic dermopathies: A retrospective review of cutaneous response to haematologic therapy. Journal Of The European Academy Of Dermatology And Venereology 2025 PMID: 40916947, DOI: 10.1111/jdv.70037.
Peer-Reviewed Original Research
Systemic Corticosteroid Use in Atopic Dermatitis: A Position Paper to Inform Safer Clinical Practice and Policy
Burshtein J, Bunick C, Vleugels R, Armstrong A, Golant A, Schlesinger T, Strober B, Song E, Gold L, Lebwohl M. Systemic Corticosteroid Use in Atopic Dermatitis: A Position Paper to Inform Safer Clinical Practice and Policy. Journal Of Investigative Dermatology 2025 PMID: 40914897, DOI: 10.1016/j.jid.2025.08.002.
Peer-Reviewed Original Research
Concepts
Replacement of Beta Cells for Type 1 Diabetes
Herold K, Pober J. Replacement of Beta Cells for Type 1 Diabetes. New England Journal Of Medicine 2025, 393: 917-921. PMID: 40902169, DOI: 10.1056/nejme2507578.
Peer-Reviewed Original Research
Concepts
The prevalence of endometriosis in adult female patients with hidradenitis suppurativa: a cross-sectional study using the All of Us Research Programme
Hodelin C, Cohen J, Eisenstein A. The prevalence of endometriosis in adult female patients with hidradenitis suppurativa: a cross-sectional study using the All of Us Research Programme. Clinical And Experimental Dermatology 2025, llaf395. PMID: 40898779, DOI: 10.1093/ced/llaf395.
Peer-Reviewed Original Research
Concepts
New Gene-based Classification of Ichthyoses and Palmoplantar Keratodermas: Hereditary Epidermal Differentiation Disorders
Paller A, Akiyama M, Hernández-Martín Á, Mazereeuw-Hautier J, Sprecher E, Initiative R, Akiyama M, Aldwin-Easton M, Bodemer C, Choate K, Fischer J, Gostynski A, Martín A, Hovnanian A, Ishida-Yamamoto A, Mazereeuw-Hautier J, O´Toole E, Paller A, Schmuth M, Sprecher E, Schwartz J, Tadini G, Teng J. New Gene-based Classification of Ichthyoses and Palmoplantar Keratodermas: Hereditary Epidermal Differentiation Disorders. Journal Of The American Academy Of Dermatology 2025 PMID: 40907761, DOI: 10.1016/j.jaad.2025.08.086.
Peer-Reviewed Original Research
Concepts
64524 Long-Term Safety of Ruxolitinib Cream in Adults and Adolescents With Mild-to-Moderate Atopic Dermatitis: Adverse Events of Interest From the TRuE-AD1 and TRuE-AD2 Phase 3 Studies
Simpson E, Kircik L, Eichenfield L, Bunick C, Boguniewicz M, Kallender H, Sturm D, Jackson T, Ren H, Blauvelt A. 64524 Long-Term Safety of Ruxolitinib Cream in Adults and Adolescents With Mild-to-Moderate Atopic Dermatitis: Adverse Events of Interest From the TRuE-AD1 and TRuE-AD2 Phase 3 Studies. Journal Of The American Academy Of Dermatology 2025, 93: ab245. DOI: 10.1016/j.jaad.2025.05.973.
Peer-Reviewed Original Research
Concepts
62400 Rapid Itch Relief with Upadacitinib vs Dupilumab in Adults and Adolescents with Moderate-to-Severe Atopic Dermatitis: Results from the Phase 3b/4 Level Up Study
Bunick C, Kwatra S, Lima H, Abe M, Song E, Ibrahim N, Sanchez C, Vigna N, Lane M, Calimlim B, Ständer S. 62400 Rapid Itch Relief with Upadacitinib vs Dupilumab in Adults and Adolescents with Moderate-to-Severe Atopic Dermatitis: Results from the Phase 3b/4 Level Up Study. Journal Of The American Academy Of Dermatology 2025, 93: ab281. DOI: 10.1016/j.jaad.2025.05.1115.
Peer-Reviewed Original Research
Concepts
63516 Higher Levels of Skin Clearance Across Body Regions with Upadacitinib versus Dupilumab in Patients with Moderate-to-Severe Atopic Dermatitis
Eyerich K, Torres T, Lynde C, Bunick C, Moore A, Vigna N, Calimlim B, Wu X, Ibrahim N, Sancho C, Silverberg J. 63516 Higher Levels of Skin Clearance Across Body Regions with Upadacitinib versus Dupilumab in Patients with Moderate-to-Severe Atopic Dermatitis. Journal Of The American Academy Of Dermatology 2025, 93: ab218. DOI: 10.1016/j.jaad.2025.05.865.
Peer-Reviewed Original Research
Concepts

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