2023
Chemiexcitation: Mammalian Photochemistry in the Dark†
Brash D, Goncalves L. Chemiexcitation: Mammalian Photochemistry in the Dark†. Photochemistry And Photobiology 2023, 99: 251-276. PMID: 36681894, PMCID: PMC10065968, DOI: 10.1111/php.13781.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsExcited statesMammalian cellsCyclobutane pyrimidine dimersEvolutionary selectionBond rearrangementUnoccupied orbitalsGround stateReaction productsPyrimidine dimersChemiexcitationRecent findingsBiologyPathogenic eventsRadicalsUltraviolet lightMoleculesDrug-induced deafnessPotential pathogenesisCellsMelaninAchilles heelMammalsBiomoleculesPhotochemistryDNA
2018
Chemiexcitation and Its Implications for Disease
Brash DE, Goncalves LCP, Bechara EJH, Group T. Chemiexcitation and Its Implications for Disease. Trends In Molecular Medicine 2018, 24: 527-541. PMID: 29751974, PMCID: PMC5975183, DOI: 10.1016/j.molmed.2018.04.004.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsHigh-energy processesQuantum mechanicsMolecular orbitalsTransfer energyHighest energy molecular orbitalChemiexcitationUltraviolet lightMutagenic cyclobutane pyrimidine dimersNumerous human diseasesPhotonsElectronsCyclobutane pyrimidine dimersOrbitalsHuman diseasesUpstream eventsPigment melaninEnergy