2017
Predictors of tanning dependence in white non‐Hispanic females and males
Cartmel B, Bale AE, Mayne ST, Gelernter JE, DeWan AT, Spain P, Leffell DJ, Pagoto S, Ferrucci LM. Predictors of tanning dependence in white non‐Hispanic females and males. Journal Of The European Academy Of Dermatology And Venereology 2017, 31: 1223-1228. PMID: 28129487, PMCID: PMC5522341, DOI: 10.1111/jdv.14138.Peer-Reviewed Original ResearchConceptsEarly-onset basal cell carcinomaCase-control studyBasal cell carcinomaWhite non-Hispanic femalesSymptoms of dependenceCell carcinomaNon-Hispanic femalesAlcohol dependenceMental disordersAppropriate interventionsHost factorsNon-HispanicsStatistical ManualMultivariate modelIndoor tanningSignificant predictorsOnline surveyFourth EditionPredictorsEuropean ancestryQuestionnaireEye openerEye colorParticipantsCarcinoma
2016
Body mass index, height and early-onset basal cell carcinoma in a case-control study
Zhang Y, Cartmel B, Choy CC, Molinaro AM, Leffell DJ, Bale AE, Mayne ST, Ferrucci LM. Body mass index, height and early-onset basal cell carcinoma in a case-control study. Cancer Epidemiology 2016, 46: 66-72. PMID: 28039770, PMCID: PMC5272867, DOI: 10.1016/j.canep.2016.12.007.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBody HeightBody Mass IndexCarcinoma, Basal CellCase-Control StudiesChildFemaleHumansMaleSkin NeoplasmsYoung AdultConceptsEarly-onset basal cell carcinomaBody mass indexBasal cell carcinomaMass indexCell carcinomaInverse associationOdds ratioAdult heightUnconditional logistic regression modelsAdult body mass indexBenign skin conditionsMultivariate odds ratiosSimilar inverse associationsConfidence intervalsCase-control studySignificant inverse associationLogistic regression modelsUltraviolet radiation exposurePrior UV exposureCommon malignancyControl subjectsUV exposureBiopsy siteMedical characteristicsSkin conditions
2015
Family history of skin cancer is associated with early-onset basal cell carcinoma independent of MC1R genotype
Berlin NL, Cartmel B, Leffell DJ, Bale AE, Mayne ST, Ferrucci LM. Family history of skin cancer is associated with early-onset basal cell carcinoma independent of MC1R genotype. Cancer Epidemiology 2015, 39: 1078-1083. PMID: 26381319, PMCID: PMC4679454, DOI: 10.1016/j.canep.2015.09.005.Peer-Reviewed Original ResearchConceptsEarly-onset basal cell carcinomaBasal cell carcinomaFamily historySkin cancerAge of onsetLifestyle factorsBenign skin conditionsStrong risk factorFirst-degree relativesMC1R genotypeCell carcinomaRisk factorsAge 40High riskLifestyle characteristicsAge 50Particular malignancySkin conditionsBCC casesCancerGenetic susceptibilitySaliva samplesMultivariate modelIndividual riskAffected relativesIndoor Tanning and the MC1R Genotype: Risk Prediction for Basal Cell Carcinoma Risk in Young People
Molinaro AM, Ferrucci LM, Cartmel B, Loftfield E, Leffell DJ, Bale AE, Mayne ST. Indoor Tanning and the MC1R Genotype: Risk Prediction for Basal Cell Carcinoma Risk in Young People. American Journal Of Epidemiology 2015, 181: 908-916. PMID: 25858289, PMCID: PMC4445390, DOI: 10.1093/aje/kwu356.Peer-Reviewed Original ResearchConceptsRisk prediction modelCancer risk prediction modelsIndoor tanningBasal cell carcinoma incidenceBasal cell carcinoma riskNovel risk prediction modelRisk of BCCRisk predictionCase-control studyNon-Hispanic whitesLogistic regression modelsCancer risk predictionSignificant morbidityCarcinoma incidenceAdjusted areaCarcinoma riskIndependent cohortYoung individualsTreatment costsMC1R variantsYoung peopleReceptor geneCharacteristic curve
2014
Alcohol intake and early‐onset basal cell carcinoma in a case–control study
Zhang Y, Ferrucci LM, Cartmel B, Molinaro AM, Leffell DJ, Bale AE, Mayne ST. Alcohol intake and early‐onset basal cell carcinoma in a case–control study. British Journal Of Dermatology 2014, 171: 1451-1457. PMID: 25059635, PMCID: PMC4272627, DOI: 10.1111/bjd.13291.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge of OnsetAlcohol DrinkingCarcinoma, Basal CellCase-Control StudiesFemaleHumansMaleSkin NeoplasmsSunbathingSunlightUltraviolet RaysConceptsEarly-onset basal cell carcinomaBasal cell carcinomaLifetime alcohol intakeAlcohol intakeCell carcinomaOdds ratioEpidemiological studiesConfidence intervalsBasal cell carcinoma casesUnconditional multivariate logistic regressionBenign skin conditionsMultivariate logistic regressionOverall alcohol intakeCase-control studyPrevious epidemiological studiesYears of ageType of beverageCarcinoma casesUV exposureHigh riskSkin conditionsSignificant associationLogistic regressionRisk estimatesIntakeNovel gene identified in an exome‐wide association study of tanning dependence
Cartmel B, Dewan A, Ferrucci LM, Gelernter J, Stapleton J, Leffell DJ, Mayne ST, Bale AE. Novel gene identified in an exome‐wide association study of tanning dependence. Experimental Dermatology 2014, 23: 757-759. PMID: 25041255, PMCID: PMC4204712, DOI: 10.1111/exd.12503.Peer-Reviewed Original ResearchTea, coffee, and caffeine and early-onset basal cell carcinoma in a case–control study
Ferrucci LM, Cartmel B, Molinaro AM, Leffell DJ, Bale AE, Mayne ST. Tea, coffee, and caffeine and early-onset basal cell carcinoma in a case–control study. European Journal Of Cancer Prevention 2014, 23: 296-302. PMID: 24841641, PMCID: PMC4059399, DOI: 10.1097/cej.0000000000000037.Peer-Reviewed Original ResearchConceptsEarly-onset basal cell carcinomaBasal cell carcinomaCase-control studyCell carcinomaDermatopathology databaseOdds ratioRegular consumptionRisk of BCCMultivariate odds ratiosSquamous cell carcinomaUnconditional logistic regressionConfidence intervalsModest protective effectHot teaNon-Hispanic whitesPotential health benefitsEpidemiologic evidenceInverse associationProtective effectBiopsy siteAge 40Caffeinated coffeeSkin carcinogenesisBCC casesProtective roleSystemic glucocorticoid use and early-onset basal cell carcinoma
Troche JR, Ferrucci LM, Cartmel B, Leffell DJ, Bale AE, Mayne ST. Systemic glucocorticoid use and early-onset basal cell carcinoma. Annals Of Epidemiology 2014, 24: 625-627. PMID: 24958637, PMCID: PMC4119504, DOI: 10.1016/j.annepidem.2014.05.009.Peer-Reviewed Original Research
2012
Lifetime history of indoor tanning in young people: a retrospective assessment of initiation, persistence, and correlates
Lostritto K, Ferrucci LM, Cartmel B, Leffell DJ, Molinaro AM, Bale AE, Mayne ST. Lifetime history of indoor tanning in young people: a retrospective assessment of initiation, persistence, and correlates. BMC Public Health 2012, 12: 118. PMID: 22324969, PMCID: PMC3340300, DOI: 10.1186/1471-2458-12-118.Peer-Reviewed Original Research
2011
Indoor tanning and risk of early-onset basal cell carcinoma
Ferrucci LM, Cartmel B, Molinaro AM, Leffell DJ, Bale AE, Mayne ST. Indoor tanning and risk of early-onset basal cell carcinoma. Journal Of The American Academy Of Dermatology 2011, 67: 552-562. PMID: 22153793, PMCID: PMC3307842, DOI: 10.1016/j.jaad.2011.11.940.Peer-Reviewed Original ResearchConceptsEarly-onset basal cell carcinomaBasal cell carcinomaIndoor tanningCell carcinomaOdds ratioMultiple basal cell carcinomasBenign skin conditionsStrong risk factorConfidence intervalsMultivariate logistic regressionPotential recall biasYears of ageExposure-disease relationshipsIndoor tanning devicesAge of initiationRisk factorsBiopsy siteEpidemiologic studiesSkin conditionsReferent groupControl populationTanning devicesLogistic regressionRecall biasIndoor tannersHost Phenotype Characteristics and MC1R in Relation to Early-Onset Basal Cell Carcinoma
Ferrucci LM, Cartmel B, Molinaro AM, Gordon PB, Leffell DJ, Bale AE, Mayne ST. Host Phenotype Characteristics and MC1R in Relation to Early-Onset Basal Cell Carcinoma. Journal Of Investigative Dermatology 2011, 132: 1272-1279. PMID: 22158557, PMCID: PMC3305835, DOI: 10.1038/jid.2011.402.Peer-Reviewed Original ResearchConceptsDermatopathology databaseSkin reactionsCase statusBasal cell carcinoma incidenceMelanocortin 1 receptor gene variantsNon-synonymous variantsBenign skin conditionsBasal cell carcinomaReceptor gene variantsCarcinoma incidenceCell carcinomaBCC riskEpidemiologic studiesSelf-reported phenotypesLower riskSkin conditionsBCC casesSkin cancerOlder populationYoung individualsGene variantsPhenotype-genotype interactionsHost characteristicsPhenotype characteristicSkin color