Salpingectomy for Ovarian Cancer Risk Reduction: Improving Utilization and Informed Decision-Making
New evidence on ovarian carcinogenesis shows that most ovarian cancers originate from the fallopian tubes rather than from the ovaries. This reveals a better opportunity for ovarian cancer prevention – prophylactic salpingectomy (removing the fallopian tubes while preserving the ovaries), which can effectively reduce ovarian cancer risk without the detrimental effects of hormonal deprivation. The overarching objective of this project is to improve quality of care for prophylactic salpingectomy by identifying provider- and patient-related barriers to utilization and promoting informed decision-making. Our specific aims are: 1) to identify distinct practice phenotypes in adopting prophylactic salpingectomy among physicians and compare physician attributes across these phenotypes; 2) to examine the role of social contagion among physicians in influencing salpingectomy uptake; 3) to ascertain physician perceived barriers to salpingectomy uptake and shared decision-making; and 4) to evaluate quality of decision-making regarding prophylactic salpingectomy from patients’ perspective and identify influencing factors.
Developing A Digital Tool to Support Lung Cancer Screening
The goals of this project are to develop, test, and refine a digital tool to engage patients in lung cancer screening.
Development of Cancer Survivorship Risk Models to Inform Pathways of Care
Supporting Personalized Decision-Making for Breast Cancer Screening for Older Women
In this multi-method research study, we will evaluate how patients and providers understand and incorporate new risk assessment technologies into clinical decisions for prostate cancer. First, using population-level administrative claims data, we will define contemporary adoption patterns and study the association of prostate MRI and/or genomic testing with the initial management received by the patient. Then, to understand how both patients and providers perceive of these technologies in the process of decision-making, we will conduct in-depth, semi-structured qualitative interviews of patients with prostate cancer, as well as physicians who treat prostate cancer.
Funding source: National Institutes of Health (National Cancer Institute)
Principal Investigator: Michael Leapman