Addictive Behaviors

PET Imaging of Microglia with [11C]PBR28 in Opioid Dependent and Healthy Control Subjects

Volunteers
Health Professionals

What is the purpose of this trial?

This study aims to examine inflammation processes in the brain (neuroinflammatory and microglia markers). The proposed study will fill a major gap in our understanding of opioid addiction. The study entails a screening, mri, and PET scans. This study may also include an inpatient or outpatient treatment with buprenorphine maintenance therapy for opioid dependent participants.

Trial with
Yale University School of Medicine and National Institute on Drug Abuse (NIDA)
Ages
21 years - 45 years
Gender
Both

Find out more about who can participate in this trial

Contact Information

For more information about this study, including how to volunteer, contact Marc Grasso

marc.grasso@yale.edu

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Principal Investigator

Kelly Cosgrove, PhD
Professor of Psychiatry and of Neuroscience and of Radiology and Biomedical Imaging; Co-Director of the T32 Translational Alcohol Research Program, Psychiatry and Public Health

Sub-Investigators

Last Updated
10/17/2024
Study HIC
#2000023881