Rachel Dreyer, PhD
Assistant Professor AdjunctCards
Contact Info
About
Titles
Assistant Professor Adjunct
Biography
Dr Dreyer is a Clinical Research Scientist at Facebook Reality Labs (Health Technology). In her role at Meta she is developing and executing Digital health projects aimed at improving health outcomes throughout the world. Previously, Dr. Dreyer was full time faculty at Yale, during which time she sought to improve health care quality by accelerating the implementation of patient-centered outcomes research. More specifically, her work has pioneered efforts to improve outcomes for patients with heart disease, with a focus on understanding disparities in women. Her work has been featured in various high impact journals including JAMA and Circulation and she is an Affiliate reviewer for Medrxiv (Pre-print server for health sciences, BMJ, Yale University). Dr Dreyer remains adjunct faculty at the Yale Schools of Medicine and Public Health where she continues to collaborate with colleagues in academia. She received her BSc and PhD (Clinical research/Epidemiology) at the University of Adelaide.
Departments & Organizations
- Emergency Medicine York Street Campus Faculty
Education & Training
- PhD
- University of Adelaide (Australia) (2013)
- BS (Hon)
- University of Adelaide (Australia) (2007)
Research
Overview
Medical Research Interests
Public Health Interests
ORCID
0000-0003-2861-1383
Research at a Glance
Yale Co-Authors
Publications Timeline
Research Interests
Harlan Krumholz, MD, SM
Erica Spatz, MD, MHS
Gail D'Onofrio, MD, MS
Mary Geda, BSN, MSN, RN
Judith Lichtman, PhD, MPH
Yuan Lu, ScD
Healthcare Disparities
Publications
2024
Predictors of Health-Related Quality of Life Among Women Participating in an Appointment-Based Cardiac Rehabilitation Program.
Wright C, Fournier S, Deng Y, Meng C, Tucker K, Spatz E, Lichtman J, Zhu C, Dreyer R, Oen-Hsiao J. Predictors of Health-Related Quality of Life Among Women Participating in an Appointment-Based Cardiac Rehabilitation Program. The Journal Of Cardiovascular Nursing 2024 PMID: 38595128, DOI: 10.1097/jcn.0000000000001096.Peer-Reviewed Original ResearchConceptsHealth-related quality of lifeCR programSF-36 scoresSF-36Quality of lifeCardiac rehabilitationPredictors of health-related quality of lifeYale New Haven HealthShort-Form General Health SurveyCardiac rehabilitation programGeneral Health SurveyHealth-related qualityCardiovascular diseaseMultivariate linear regression modelChronic obstructive pulmonary diseaseMeasure HRQoL.CR adherenceCR entryPredictors of improvementRehabilitation programHealth outcomesHealth SurveyEvaluate sex differencesObstructive pulmonary diseaseSocioeconomic statusAssociation of marital/partner status with hospital readmission among young adults with acute myocardial infarction.
Zhu C, Dreyer R, Li F, Spatz E, Caraballo C, Mahajan S, Raparelli V, Leifheit E, Lu Y, Krumholz H, Spertus J, D'Onofrio G, Pilote L, Lichtman J. Association of marital/partner status with hospital readmission among young adults with acute myocardial infarction. PLOS ONE 2024, 19: e0287949. PMID: 38277368, PMCID: PMC10817183, DOI: 10.1371/journal.pone.0287949.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsMarital/partner statusPsychosocial factorsAcute myocardial infarctionYoung adultsHospital dischargeYear of hospital dischargeYoung acute myocardial infarctionAssociated with 1.3-foldCohort of young adultsLong-term readmissionCox proportional hazards modelsStatus interactionSimilar-aged menMyocardial infarctionProportional hazards modelUnpartnered statusPatient interviewsPhysician panelCardiovascular healthHospital readmissionSocioeconomic factorsAMI survivorsSequential adjustmentCardiac readmissionMultiple imputation
2023
Sex Difference in Outcomes of Acute Myocardial Infarction in Young Patients
Sawano M, Lu Y, Caraballo C, Mahajan S, Dreyer R, Lichtman J, D'Onofrio G, Spatz E, Khera R, Onuma O, Murugiah K, Spertus J, Krumholz H. Sex Difference in Outcomes of Acute Myocardial Infarction in Young Patients. Journal Of The American College Of Cardiology 2023, 81: 1797-1806. PMID: 37137590, DOI: 10.1016/j.jacc.2023.03.383.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsAcute myocardial infarctionNoncardiac hospitalizationsSubdistribution HRYounger patientsMyocardial infarctionSex differencesYoung womenCause-specific hospitalizationsCause of hospitalizationWorse health statusSignificant sex disparityNoncardiovascular hospitalizationsVIRGO StudyIndex episodeAdverse outcomesIncidence rateHospitalizationHigh riskSex disparitiesHealth statusPatientsU.S. hospitalsWomenInfarctionOutcomesSex Differences in Symptom Complexity and Door-to-Balloon Time in Patients With ST-Elevation Myocardial Infarction
Brush J, Chaudhry S, Dreyer R, D'Onofrio G, Greene E, Hajduk A, Lu Y, Krumholz H. Sex Differences in Symptom Complexity and Door-to-Balloon Time in Patients With ST-Elevation Myocardial Infarction. The American Journal Of Cardiology 2023, 197: 101-107. PMID: 37062667, PMCID: PMC10198892, DOI: 10.1016/j.amjcard.2023.03.009.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsPercutaneous coronary interventionD2B timeSymptom complexityYoung womenChest painBalloon timeST-elevation myocardial infarctionSILVER-AMI StudySymptom phenotypeSex differencesPain symptomsCoronary interventionOlder patientsMyocardial infarctionOlder womenSTEMIOlder menSymptom patternsPresentation delayPatientsSymptom clustersLogistic regressionSymptomsWomenMean numberAssociation of marital/partner status and patient-reported outcomes following myocardial infarction: a systematic review and meta-analysis
Zhu C, Tran P, Leifheit E, Spatz E, Dreyer R, Nyhan K, Wang S, Lichtman J. Association of marital/partner status and patient-reported outcomes following myocardial infarction: a systematic review and meta-analysis. European Heart Journal Open 2023, 3: oead018. PMID: 36942107, PMCID: PMC10023828, DOI: 10.1093/ehjopen/oead018.Peer-Reviewed Original ResearchCitationsAltmetricConceptsPatient-reported outcome measuresMarital/partner statusPersonal recovery outcomesMyocardial infarctionHigher HRQoLMI patientsPartner statusSystematic reviewOutcome domainsRecovery outcomesSex differencesPatient-reported outcomesNewcastle-Ottawa ScaleStandardized mean differenceSymptoms of anxietyPotential sex differencesUnpartnered patientsFunctional statusSubgroup analysisEligible studiesStudy qualityOutcome measuresPeer-reviewed studiesMean differencePatientsAssociation of Sociodemographic Characteristics With 1-Year Hospital Readmission Among Adults Aged 18 to 55 Years With Acute Myocardial Infarction
Okafor C, Zhu C, Raparelli V, Murphy T, Arakaki A, D’Onofrio G, Tsang S, Smith M, Lichtman J, Spertus J, Pilote L, Dreyer R. Association of Sociodemographic Characteristics With 1-Year Hospital Readmission Among Adults Aged 18 to 55 Years With Acute Myocardial Infarction. JAMA Network Open 2023, 6: e2255843. PMID: 36787140, PMCID: PMC9929697, DOI: 10.1001/jamanetworkopen.2022.55843.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsAcute myocardial infarctionYoung adultsHospital readmissionBlack raceMyocardial infarctionRacial differencesCardiac factorsSociodemographic characteristicsBlack individualsOdds of readmissionObservational cohort studyMedical record abstractionRisk of readmissionWhite individualsAdults Aged 18Year of dischargePostdischarge readmissionVIRGO StudyCause readmissionCohort studyPrimary outcomeRecord abstractionMulticenter studyAged 18Male ratio
2022
Young Women With Acute Myocardial Infarction: Risk Prediction Model for 1-Year Hospital Readmission
Dreyer R, Arakaki A, Raparelli V, Murphy T, Tsang S, D’Onofrio G, Wood M, Wright C, Pilote L. Young Women With Acute Myocardial Infarction: Risk Prediction Model for 1-Year Hospital Readmission. CJC Open 2022, 5: 335-344. PMID: 37377522, PMCID: PMC10290947, DOI: 10.1016/j.cjco.2022.12.004.Peer-Reviewed Original ResearchCitationsConceptsAcute myocardial infarctionRisk prediction modelHospital readmissionYoung womenMyocardial infarctionYoung AMI Patients (VIRGO) studyObstructive coronary artery diseaseRisk of readmissionCongestive heart failureProspective observational studyCoronary artery diseaseYoung female patientHospital readmission riskHospital complicationsHospital stayYounger patientsArtery diseaseClinical factorsHeart failureFemale patientsReadmission riskObservational studyModest discriminationHigh riskDepressive symptomsPreScription DigitaL ThErapEutic For Patients with Insomnia (SLEEP-I): A Protocol for a Pragmatic Randomized Controlled Trial
Dreyer R, Berkowitz A, Yaggi H, Schneeberg L, Shah N, Emanuel L, Prakash K, Jeffery M, Thorndike F, Deeg M, Ervin K, Ross J. PreScription DigitaL ThErapEutic For Patients with Insomnia (SLEEP-I): A Protocol for a Pragmatic Randomized Controlled Trial. Sleep Medicine 2022, 100: s133-s134. DOI: 10.1016/j.sleep.2022.05.365.Peer-Reviewed Original ResearchThe association of marital/partner status with patient-reported health outcomes following acute myocardial infarction or stroke: Protocol for a systematic review and meta-analysis
Zhu C, Tran P, Leifheit E, Spatz E, Dreyer R, Nyhan K, Wang S, Goldstein L, Lichtman J. The association of marital/partner status with patient-reported health outcomes following acute myocardial infarction or stroke: Protocol for a systematic review and meta-analysis. PLOS ONE 2022, 17: e0267771. PMID: 36378664, PMCID: PMC9665376, DOI: 10.1371/journal.pone.0267771.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsPatient-reported outcome measuresAcute myocardial infarctionMarital/partner statusPartner statusMyocardial infarctionHealth outcomesPatient-reported health outcomesPROSPERO registration numberRisk of biasPatient-centered factorsPeer-reviewed journalsPrimary outcomeSubgroup analysisThird reviewerOutcome measuresRegistration numberLower mortalitySystematic reviewEthics approvalStrokePartner supportMale participantsInfarctionFull textOutcomesSex Differences in Clopidogrel Effects Among Young Patients With Acute Coronary Syndrome: A Role for Genetics?
Kaur A, Dreyer R, Marsh T, Thanassoulis G, Raparelli V, D’Onofrio G, Engert J, Pilote L. Sex Differences in Clopidogrel Effects Among Young Patients With Acute Coronary Syndrome: A Role for Genetics? CJC Open 2022, 4: 970-978. PMID: 36444366, PMCID: PMC9700217, DOI: 10.1016/j.cjco.2022.07.013.Peer-Reviewed Original ResearchCitationsConceptsAcute coronary syndromeUsers of clopidogrelCoronary syndromeClinical outcomesMultivariable logistic regression modelSex differencesAdverse clinical outcomesWorse clinical outcomesTime of presentationGenetic risk scoreLogistic regression modelsSex-specific impactClopidogrel usersAtherothrombotic eventsCardiac eventsYounger patientsClopidogrel effectAntiplatelet agentsClopidogrelHigh riskRisk scoreIndependent factorsRole of sexHealth outcomesReadmission
Clinical Trials
Current Trials
An Intervention to Reduce Readmission Rates in Young Women with Acute Myocardial Infarction (AMI)
HIC ID2000026617RolePrincipal InvestigatorPrimary Completion Date12/31/2023Recruiting Participants
News & Links
News
- November 01, 2022Source: American Heart Association News
Perceived discrimination increased the risk of worse health outcomes after a heart attack
- June 14, 2022
Sex Is Not a Significant Predictor of Blood Pressure Among the Elderly
- May 30, 2022Source: Eat This, Not That!
Subtle Signs of Heart Disease for Women
- May 03, 2022
Surprising Risk Factors May Predict Heart Attacks in Young Women
Related Links