Imran Quraishi, MD, PhD
Associate Professor of NeurologyCards
About
Research
Overview
Clinical projects
- Long-term ambulatory recordings from the responsive neurostimulation system (RNS) and thalamic deep brain stimulation (DBS) devices, which are implanted into the brain to treat epilepsy.
- Clinical trials of brain stimulation to treat epilepsy.
- Use of intracranial EEG from surgical epilepsy patients and from RNS to study cognitive neuroscience of language and memory.
- Seizure forecasting based on intracranial EEG biomarkers.
- Electric and magnetic source localization, including magnetoencephalography (MEG) to understand epilepsy networks.
- PET imaging with novel tracers to visualize the effects of brain stimulation and brain dysfunction in epilepsy.
Laboratory projects
- Cellular and animal models of KCNT1 potassium channelopathies
- Anti-sense oligonucleotides and new medications to treat epilepsy due to KCNT1 mutations
Medical Subject Headings (MeSH)
Clinical Care
Overview
Imran H. Quraishi, MD, PhD, is a neurologist who cares for patients with all forms of epilepsy, including those with associated developmental or genetic disorders, as well as patients undergoing evaluation for such advanced treatments as surgery and medical devices. He is devoted to seeking out better treatments. “We want to find out why epilepsy develops and how we can interfere with that process,” he says. “We also look for answers as to why patients with epilepsy develop memory loss and other cognitive difficulties.”
As a Yale School of Medicine researcher, Dr. Quraishi’s main focus is to determine how mutations in ion channel genes contribute to seizures and epilepsy. Drawing on his background in computational modeling and electrophysiology, he is assessing the role of specific ion channels in seizures and how they can be targeted with new medications. He is also applying his expertise to studies of medical devices for the treatment of epilepsy.
Seizures from epilepsy are much more common than most people realize, Dr. Quraishi says. “Most of the time we are able to control seizures and limit side effects for our patients with the appropriate medications. Our goal is to have no seizures and no side effects,” he says.
Clinical Specialties
Fact Sheets
Epilepsy in Children and Teens
Learn More on Yale MedicinePediatric Sepsis
Learn More on Yale MedicineSyncope
Learn More on Yale MedicineGuillain-Barré Syndrome
Learn More on Yale Medicine
Board Certifications
Epilepsy
- Certification Organization
- AB of Psychiatry & Neurology
- Original Certification Date
- 2016
Neurology
- Certification Organization
- AB of Psychiatry & Neurology
- Original Certification Date
- 2013