2013
Dabigatran and Kidney Disease: A Bad Combination
Knauf F, Chaknos CM, Berns JS, Perazella MA. Dabigatran and Kidney Disease: A Bad Combination. Clinical Journal Of The American Society Of Nephrology 2013, 8: 1591-1597. PMID: 23868901, PMCID: PMC3805067, DOI: 10.2215/cjn.01260213.Peer-Reviewed Original ResearchConceptsAnticoagulant effectPharmacokinetic profileOral direct thrombin inhibitorContinuous renal replacement therapyRoutine laboratory monitoringSerious bleeding eventsHigh bleeding riskReduced kidney functionRenal replacement therapyDirect thrombin inhibitorDrug Administration approvalLaboratory monitoring testsBleeding eventsBleeding riskSerious bleedingThromboembolic complicationsDose adjustmentHemodialysis cathetersKidney functionKidney diseaseReplacement therapyLaboratory monitoringAdministration approvalClinical indicationsDrug levels
1988
Impact of unusual gastrointestinal problems on the treatment of tricyclic antidepressant overdose
Rinder H, Murphy J, Higgins G. Impact of unusual gastrointestinal problems on the treatment of tricyclic antidepressant overdose. Annals Of Emergency Medicine 1988, 17: 1079-1081. PMID: 3177998, DOI: 10.1016/s0196-0644(88)80449-9.Peer-Reviewed Original ResearchConceptsTricyclic antidepressant overdoseAntidepressant overdoseGastric bypass proceduresCharcoal administrationEsophageal spasmOrogastric tubeFunctional obstructionSecond patientUnreported complicationBypass proceduresFirst patientTricyclic antidepressantsGastrointestinal abnormalitiesGastrointestinal problemsPatientsRapid absorptionOverdoseSpasmAntidepressantsComplicationsNitroglycerinObstructionTherapyAbnormalitiesAdministration
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