2025
Once-Weekly Semaglutide in Adults With Alcohol Use Disorder
Hendershot C, Bremmer M, Paladino M, Kostantinis G, Gilmore T, Sullivan N, Tow A, Dermody S, Prince M, Jordan R, McKee S, Fletcher P, Claus E, Klein K. Once-Weekly Semaglutide in Adults With Alcohol Use Disorder. JAMA Psychiatry 2025, 82: 395-405. PMID: 39937469, PMCID: PMC11822619, DOI: 10.1001/jamapsychiatry.2024.4789.Peer-Reviewed Original ResearchAlcohol use disorderUse disorderPeak breath alcohol concentrationMedium to large effect sizesNon-treatment-seeking participantsWeeks of outpatient treatmentAlcohol self-administrationSelf-administration taskReduce alcohol intakeOnce-weekly subcutaneous semaglutideLarge effect sizesAlcohol consumptionSubsample of individualsBreath alcohol concentrationEffects of once-weekly subcutaneous semaglutideTreatment-by-time interactionOnce-weekly semaglutideAlcohol cravingReduce cravingSelf-AdministrationDrinking outcomesSemaglutide treatmentDrinking daysReduce drinkingAmount of alcoholGlucagon-like peptide-1 receptor agonists but not dipeptidyl peptidase-4 inhibitors reduce alcohol intake
Farokhnia M, Tazare J, Pince C, Bruns N, Gray J, Re V, Fiellin D, Kranzler H, Koob G, Justice A, Vendruscolo L, Rentsch C, Leggio L. Glucagon-like peptide-1 receptor agonists but not dipeptidyl peptidase-4 inhibitors reduce alcohol intake. Journal Of Clinical Investigation 2025, 135: e188314. PMID: 40048376, PMCID: PMC12043080, DOI: 10.1172/jci188314.Peer-Reviewed Original ResearchAlcohol use disorderTreat alcohol use disorderGlucagon-like peptide-1 receptor agonistsPeptide-1 receptor agonistsDipeptidyl peptidase-4 inhibitorsPeptidase-4 inhibitorsDPP-4isOperant oral alcohol self-administrationDPP-4iAlcohol intakeOral alcohol self-administrationBinge-like alcohol drinkingBaseline alcohol use disordersReceptor agonistsAlcohol self-administrationAlcohol-dependent ratsReduce alcohol drinkingAlcohol drinkingGLP-1RAAlcohol Use Disorders Identification Test-Consumption (AUDIT-C) scoresReduce alcohol intakeGLP-1RAsImpact of dipeptidyl peptidase-4 inhibitorReverse translational approachBaseline hazardous drinking
2024
Examining HIV Knowledge and Sexually Risky Behaviors among Female Sex Workers in Kampala, Uganda
Ssenyonjo J, Mistler C, Adler T, Shrestha R, Kyambadde P, Copenhaver M. Examining HIV Knowledge and Sexually Risky Behaviors among Female Sex Workers in Kampala, Uganda. International Journal Of Environmental Research And Public Health 2024, 21: 163. PMID: 38397654, PMCID: PMC10888220, DOI: 10.3390/ijerph21020163.Peer-Reviewed Original ResearchConceptsFemale sex workersHealthcare providersHIV testingHIV preventionHistory of HIV testingRates of sexually transmitted infectionsCondom usageSex workersProvider-level barriersDevelopment of targeted interventionsPrimary HIV preventionHIV test resultsHealth education programsHIV transmission riskHIV prevention educationSexually transmitted infectionsHIV knowledgeHIV incidencePreventive interventionsFocus groupsTargeted interventionsReduce alcohol intakeHIV transmissionPrevention educationAlcohol intake
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply