2025
Trends and outcomes of tenecteplase and alteplase usage for ischemic stroke in the United States
Anadani M, Hamoud L, Chase B, Wang C, Kassam A, Akanda M, de Havenon A, Kassab S, Gory B, Kashiouris M, Jumaa M. Trends and outcomes of tenecteplase and alteplase usage for ischemic stroke in the United States. Clinical Neurology And Neurosurgery 2025, 258: 109150. PMID: 40967056, DOI: 10.1016/j.clineuro.2025.109150.Peer-Reviewed Original ResearchIn-Hospital MortalityIntracranial hemorrhageHome dischargeHigher oddsAcute ischemic strokeTNK groupIschemic strokeHigher likelihood of home dischargeOdds of intracranial hemorrhageSensitivity analysis restricted to patientsRate of intracranial hemorrhageStroke patients treated with intravenous thrombolysisOdds of in-hospital mortalityAssociated with home dischargeIschemic stroke patients treated with intravenous thrombolysisPatients treated with intravenous thrombolysisAssociated with higher oddsAnalysis restricted to patientsLikelihood of home dischargeRate of home dischargeTreated with alteplaseHigher likelihoodRestricted to patientsNo significant associationEndovascular therapyEndovascular Stenting for Acute Ischemic Stroke Due to Cervical Artery Dissection: Nationwide Study of Stroke Recurrence
Chen H, Khunte M, Colasurdo M, Malhotra A, Gandhi D. Endovascular Stenting for Acute Ischemic Stroke Due to Cervical Artery Dissection: Nationwide Study of Stroke Recurrence. Stroke Vascular And Interventional Neurology 2025, 5 DOI: 10.1161/svin.124.001726.Peer-Reviewed Original ResearchCervical artery dissectionRate of intracranial hemorrhageNo-stent groupStent groupIntracranial hemorrhageEndovascular stentingAcute ischemic strokeArtery dissectionRate of short-term morbidityStroke recurrenceDays of follow-upSecondary end pointsShort-term morbidityRetrospective cohort studyRate of recurrent strokeRate of stroke recurrenceMaintain vessel patencyPropensity score matchingRoutine dischargeRate of routine dischargeAdult patientsRecurrence riskLogistic regression modelsOcclusive lesionsFollow-up
2023
Trends in outcomes and racial disparities in adult hospitalizations for immune thrombocytopenia over a decade
Litvin R, Dasgupta M, Deenadayalan V, Cuartas-Mesa M, Olafimihan A, Park D, Zia M, Shaka H. Trends in outcomes and racial disparities in adult hospitalizations for immune thrombocytopenia over a decade. Annals Of Hematology 2023, 102: 1677-1686. PMID: 37147362, DOI: 10.1007/s00277-023-05249-8.Peer-Reviewed Original ResearchConceptsImmune thrombocytopeniaAutoimmune-mediated platelet destructionWhite patientsRate of intracranial hemorrhageITP managementRate of epistaxisLow platelet countRare hematologic disorderNationwide population-based studyTotal healthcare chargesDiagnosis of exclusionResponse to treatmentPopulation-based studyLength of stayNational Inpatient SampleThrombopoietin deficiencyPlatelet destructionIntracranial hemorrhagePlatelet countHematological disordersProspective studyDisease behaviorPatientsHispanic patientsHospital outcomes
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