2017
Protein Requirements for Critically Ill Patients With Renal and Liver Failure
Patel J, McClain C, Sarav M, Hamilton‐Reeves J, Hurt R. Protein Requirements for Critically Ill Patients With Renal and Liver Failure. Nutrition In Clinical Practice 2017, 32: 101s-111s. PMID: 28208022, DOI: 10.1177/0884533616687501.Peer-Reviewed Original ResearchConceptsDecompensated liver cirrhosisAcute kidney injuryAcute liver failureNegative nitrogen balanceMuscle wastingRenal replacement therapyCritically ill patientsRespiratory failureLiver dysfunctionReplacement therapyKidney injuryLiver failureLiver cirrhosisAmino acid lossesICU admissionIncreased riskOptimal protein supplementationSevere formIll patientsCritical illnessNitrogen balanceProtein abnormalitiesAssociated with proteolysisProtein requirementsAcid loss
2011
Immunohistochemical Staining for DNA Mismatch Repair Proteins in Intestinal Tract Carcinoma
Shia J, Stadler Z, Weiser M, Rentz M, Gonen M, Tang L, Vakiani E, Katabi N, Xiong X, Markowitz A, Shike M, Guillem J, Klimstra D. Immunohistochemical Staining for DNA Mismatch Repair Proteins in Intestinal Tract Carcinoma. The American Journal Of Surgical Pathology 2011, 35: 447-454. PMID: 21297438, DOI: 10.1097/pas.0b013e31820a091d.Peer-Reviewed Original ResearchMeSH KeywordsAdaptor Proteins, Signal TransducingAdenocarcinomaAdenosine TriphosphatasesAdultAgedAged, 80 and overBiomarkers, TumorBiopsyColorectal NeoplasmsDNA Mismatch RepairDNA Repair EnzymesDNA-Binding ProteinsFemaleGerm-Line MutationHumansImmunohistochemistryMaleMiddle AgedMismatch Repair Endonuclease PMS2MutL Protein Homolog 1MutS Homolog 2 ProteinNuclear ProteinsReproducibility of ResultsConceptsMismatch repair protein abnormalitiesLynch syndromeResected specimenMismatch repair proteinsPathogenic germline mutationsWeak stainingBiopsy samplesStaining patternMLH1 stainingMSH6 stainingModerate intensityProtein abnormalitiesCancer resection specimensGastrointestinal tract cancerMismatch repair abnormalitiesImmunohistochemical staining patternsConcordant staining patternSpecimens of adenocarcinomaColorectal cancerIncreased riskMSH6Loss of stainingMLH1Rectal carcinomaGermline mutations
1999
MITOP: database for mitochondria-related proteins, genes and diseases
Scharfe C, Zaccaria P, Hoertnagel K, Jaksch M, Klopstock T, Lill R, Prokisch H, Gerbitz K, Mewes HW, Meitinger T. MITOP: database for mitochondria-related proteins, genes and diseases. Nucleic Acids Research 1999, 27: 153-155. PMID: 9847163, PMCID: PMC148118, DOI: 10.1093/nar/27.1.153.Peer-Reviewed Original ResearchConceptsGene catalogProtein entriesMitochondrial-encoded genesMitochondria-related proteinsCaenorhabditis elegansProtein catalogueEST hitsMitochondrial processesNeurospora crassaFASTA searchInterspecies homologyMus musculusReference sequenceHomologyGenesProteinFacilitate investigationProtein abnormalitiesSequenceElegansCrassaCerevisiaeMusculusSpeciesPathway
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