2025
Pregnenolone reduces provoked craving and cocaine use in men and women with cocaine use disorder: A pilot trial
Sakmar E, Wemm S, Fogelman N, Hermes G, Sinha R, Milivojevic V. Pregnenolone reduces provoked craving and cocaine use in men and women with cocaine use disorder: A pilot trial. Drug And Alcohol Dependence 2025, 274: 112765. PMID: 40570771, PMCID: PMC12264926, DOI: 10.1016/j.drugalcdep.2025.112765.Peer-Reviewed Original ResearchCocaine use disorderCocaine useNeuroactive steroidsUse disorderTreatment of cocaine use disorderCocaine use outcomePregnenolone levelsTreatment-seeking individualsDays of cocaineChronic cocaine useExposure to stressPreg groupCocaine cuesCocaine cravingCraving responsesNeutral cuesInduce cravingCravingWeek 2CocaineChronic treatmentPilot findingsCocaine amountPrecursor pregnenoloneLinear mixed effects modelsPilot Findings From the First Legalized Mobile Retail Pharmacy Clinic in the United States for Infectious Disease Treatment and Prevention Tailored to Reach People Who Use Drugs
Tarfa A, Di Paola A, Frank C, Schultheis A, Brooks R, Shenoi S, Springer S. Pilot Findings From the First Legalized Mobile Retail Pharmacy Clinic in the United States for Infectious Disease Treatment and Prevention Tailored to Reach People Who Use Drugs. Open Forum Infectious Diseases 2025, 12: ofaf200. PMID: 40276721, PMCID: PMC12019630, DOI: 10.1093/ofid/ofaf200.Peer-Reviewed Original ResearchHuman immunodeficiency virusHepatitis C virusOpioid use disorderAntiretroviral therapyViral loadHepatitis C virus viral loadTested HIVHuman immunodeficiency virus diagnosisSexually transmitted infection testingHepatitis C virus antibodyModerate to severe opioid use disorderDirect-acting antiviralsSevere opioid use disorderHIV antiretroviral therapyInfectious disease treatmentHCV VLImmunodeficiency virusPreexposure prophylaxisCommunity health workersPilot findingsC virusPostexposure prophylaxisHCV testingPositive testSubstance use disorders
2024
Stability and Reliability of Repeated Plasma Pregnenolone Levels After Oral Pregnenolone Dosing in Individuals with Cocaine Use Disorder: Pilot Findings
Gao H, Magin Z, Fogelman N, Sinha R, Angarita G, Milivojevic V. Stability and Reliability of Repeated Plasma Pregnenolone Levels After Oral Pregnenolone Dosing in Individuals with Cocaine Use Disorder: Pilot Findings. Life 2024, 14: 1483. PMID: 39598281, PMCID: PMC11595496, DOI: 10.3390/life14111483.Peer-Reviewed Original ResearchCocaine use disorderSubstance use disordersUse disorderPregnenolone levelsTreatment of cocaine use disorderReduce alcohol cravingTreatment-seeking individualsAssociated across timeAdministration of pregnenoloneEight-week trialSignificant main effectAlcohol cravingPregnenolone administrationNegative health risksDouble-blind clinical trialMain effectPilot findingsLevels of pregnenoloneChronic dosingStudy medication doseMedication dosesDisordersCocainePilot studyStress biology
1992
Behavioral Treatment of Children and Adolescents with Trichotillomania
VITULANO L, KING R, SCAHILL L, COHEN D. Behavioral Treatment of Children and Adolescents with Trichotillomania. Journal Of The American Academy Of Child & Adolescent Psychiatry 1992, 31: 139-146. PMID: 1537765, DOI: 10.1097/00004583-199201000-00021.Peer-Reviewed Original ResearchConceptsStandard psychiatric careBehavioral treatment programTreatment modalitiesPsychiatric careBehavior disorderBehavioral treatmentTreatment programPilot findingsRelative safetyTrichotillomaniaBehavioral techniquesPotential effectivenessChildrenAdolescentsUseful rolePatientsPharmacologicalDisfigurementScalpCare
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