2025
Pilot Findings From the First Legalized Mobile Retail Pharmacy Clinic in the United States for Infectious Disease Treatment and Prevention Tailored to Reach People Who Use Drugs
Tarfa A, Di Paola A, Frank C, Schultheis A, Brooks R, Shenoi S, Springer S. Pilot Findings From the First Legalized Mobile Retail Pharmacy Clinic in the United States for Infectious Disease Treatment and Prevention Tailored to Reach People Who Use Drugs. Open Forum Infectious Diseases 2025, 12: ofaf200. PMID: 40276721, PMCID: PMC12019630, DOI: 10.1093/ofid/ofaf200.Peer-Reviewed Original ResearchHuman immunodeficiency virusHepatitis C virusOpioid use disorderAntiretroviral therapyViral loadHepatitis C virus viral loadTested HIVHuman immunodeficiency virus diagnosisSexually transmitted infection testingHepatitis C virus antibodyModerate to severe opioid use disorderDirect-acting antiviralsSevere opioid use disorderHIV antiretroviral therapyInfectious disease treatmentHCV VLImmunodeficiency virusPreexposure prophylaxisCommunity health workersPilot findingsC virusPostexposure prophylaxisHCV testingPositive testSubstance use disorders
2024
HIV and Substance Use Disorders
Lier A, Tarfa A, Shenoi S, Kuo I, Springer S. HIV and Substance Use Disorders. Infectious Disease Clinics Of North America 2024, 38: 599-611. PMID: 38960783, PMCID: PMC11410345, DOI: 10.1016/j.idc.2024.06.003.Peer-Reviewed Original ResearchHuman immunodeficiency virusSubstance use disordersEvidence-based public health effortsHuman immunodeficiency virus acquisitionHuman immunodeficiency virus incidenceRisk of HIV acquisitionUntreated substance use disordersPoor HIV outcomesAdherence to HIV antiretroviral therapyHIV antiretroviral therapyPublic health effortsInjection drug useAntiretroviral therapyHIV acquisitionImmunodeficiency virusHIV outcomesHealth effortsTreatment strategiesIncreased riskDrug useSubstance useDrugAmericanRiskPersons
2020
Adherence to HIV antiretroviral therapy among pregnant and postpartum women during the Option B+ era: 12‐month cohort study in urban South Africa and rural Uganda
Matthews L, Orrell C, Bwana M, Tsai A, Psaros C, Asiimwe S, Amanyire G, Musinguzi N, Bell K, Bangsberg D, Haberer J, April N, Mpahleni A, Situlo V, Mzamo S, Ngwenya N, Panda K, Linda T, Atwiine C, Moonight S, Tindimwebwa E, Mugisha N, Atwogeire P, Namana V, Kyampaire C, Nuwagaba G, Kembabazi A, Mugisha S, Nanfuka V, Cross A, Kelly N, Moralie D, Cogill D, Ashaba J, Xapa Z, Orimwesiga M, Tuhanamagyezi E, Mpanga D, Kyarisima L, Kigozi S, October E, Mugisha S, Kiviiri I, Ware N, Elioda T, Siedner M, Katz I, Wyatt M. Adherence to HIV antiretroviral therapy among pregnant and postpartum women during the Option B+ era: 12‐month cohort study in urban South Africa and rural Uganda. Journal Of The International AIDS Society 2020, 23: e25586. PMID: 32820622, PMCID: PMC7441010, DOI: 10.1002/jia2.25586.Peer-Reviewed Original ResearchConceptsAnti-retroviral therapyNever-pregnant womenHIV RNAFollow-upMonth of pregnancyEver-pregnantNon-pregnantMedian adherenceCohort studyPostpartum womenHigher CD4 cell countRural UgandaPoor adherenceMedian ART adherenceNon-pregnancy-relatedOption B+ eraHIV RNA suppressionCD4 cell countUrban South AfricaPostpartum follow-upFollow-up timeAnti-retroviral therapy adherenceAssociated with younger ageAdherence to HIV antiretroviral therapyHIV antiretroviral therapy
2019
Perspective on potential impact of HIV central nervous system latency on eradication.
Chan P, Ananworanich J. Perspective on potential impact of HIV central nervous system latency on eradication. AIDS 2019, 33 Suppl 2: s123-s133. PMID: 31090545, DOI: 10.1097/qad.0000000000002264.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsAntiretroviral therapyEarly antiretroviral therapyHIV antiretroviral therapyLife-long adherencePossibility of comorbidityART interruptionCNS persistenceHIV eradicationNeurological safetyTreatment interruptionHIV remissionNeurocognitive disordersRemission studiesExperimental agentsHIVEradicationTherapyRemissionComorbiditiesAgents
2016
Malaria in HIV-Infected Children Receiving HIV Protease-Inhibitor- Compared with Non-Nucleoside Reverse Transcriptase Inhibitor-Based Antiretroviral Therapy, IMPAACT P1068s, Substudy to P1060
Hobbs CV, Gabriel EE, Kamthunzi P, Tegha G, Tauzie J, Petzold E, Barlow-Mosha L, H. BH, Li Y, Ilmet T, Kirmse B, Neal J, Parikh S, Deygoo N, Philippe P, Mofenson L, Prescott W, Chen J, Musoke P, Palumbo P, Duffy PE, Borkowsky W, Team F. Malaria in HIV-Infected Children Receiving HIV Protease-Inhibitor- Compared with Non-Nucleoside Reverse Transcriptase Inhibitor-Based Antiretroviral Therapy, IMPAACT P1068s, Substudy to P1060. PLOS ONE 2016, 11: e0165140. PMID: 27936233, PMCID: PMC5147802, DOI: 10.1371/journal.pone.0165140.Peer-Reviewed Original ResearchMeSH KeywordsAntimalarialsCD4 Lymphocyte CountChildChild, PreschoolCoinfectionDrug Therapy, CombinationFemaleHIV InfectionsHIV Protease InhibitorsHIV-1HumansInfantLamivudineLopinavirMalaria, FalciparumMalawiMaleNevirapinePlasmodium falciparumReverse Transcriptase InhibitorsRitonavirViral LoadZidovudineConceptsNon-nucleoside reverse transcriptase inhibitorAntiretroviral therapyReverse transcriptase inhibitorBlood smear microscopyHIV protease inhibitorsPositive BSTranscriptase inhibitorProtease inhibitorsClinical malaria incidenceMalaria parasite carriageMalaria-endemic settingsHIV antiretroviral therapyAnti-malarial treatmentLopinavir-ritonavirIllness visitsParasite carriageMalaria treatmentClinical studiesSmear microscopyLower riskMalaria incidenceFurther evaluationMalaria parasitesHIVMonths
2015
The epidemiological impact of HIV antiretroviral therapy on malaria in children
Greenhalgh S, Ndeffo M, Galvani AP, Parikh S. The epidemiological impact of HIV antiretroviral therapy on malaria in children. AIDS 2015, 29: 473-482. PMID: 25486414, PMCID: PMC4391884, DOI: 10.1097/qad.0000000000000550.Peer-Reviewed Original ResearchConceptsHIV protease inhibitorsRecurrent malariaMalaria transmissionAntiretroviral therapyArtemether-lumefantrineAnnual incidenceProtease inhibitorsFirst-line antiretroviral regimenFirst-line antiretroviral therapyArtemether-lumefantrine treatmentHIV-negative childrenFirst-line antimalarialsHIV prevalence settingsHIV antiretroviral therapyRecent clinical trialsHIV prevalence levelsMalaria transmission settingsMalaria transmission intensityAntiretroviral regimenAntimalarial treatmentHIV prevalenceProphylactic effectPrevalence settingsClinical trialsHealth burden
2001
Public Health Consequences of Screening Patients for Adherence to Highly Active Antiretroviral Therapy
Tchetgen E, Kaplan E, Friedland G. Public Health Consequences of Screening Patients for Adherence to Highly Active Antiretroviral Therapy. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2001, 26: 118-129. DOI: 10.1097/00126334-200102010-00003.Peer-Reviewed Original ResearchConceptsActive antiretroviral therapyAntiretroviral therapyDrug resistanceDrug-resistant virusesNew HIV infectionsHIV antiretroviral therapyImportance of adherencePublic health consequencesHIV patientsHIV infectionTreatment regimensScreening patientsAIDS casesPatient benefitPhysician's abilityPatientsAIDS incidenceTherapyHealth consequencesAdherenceRecent studiesPopulation levelHAARTRegimensHIVPublic Health Consequences of Screening Patients for Adherence to Highly Active Antiretroviral Therapy
Tchetgen E, Kaplan E, Friedland G. Public Health Consequences of Screening Patients for Adherence to Highly Active Antiretroviral Therapy. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2001, 26: 118-129. PMID: 11242178, DOI: 10.1097/00042560-200102010-00003.Peer-Reviewed Original ResearchConceptsActive antiretroviral therapyAntiretroviral therapyDrug resistanceDrug-resistant virusesNew HIV infectionsHIV antiretroviral therapyImportance of adherencePublic health consequencesHIV patientsHIV infectionTreatment regimensScreening patientsAIDS casesPatient benefitPhysician's abilityPatientsAIDS incidenceTherapyHealth consequencesAdherenceRecent studiesPopulation levelHAARTRegimensHIV
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