2025
Long-term neurocognitive and behavioral outcomes in patients with non-syndromic craniosynostosis
Ihnat J, Hu K, Goss J, Allam O, Parikh N, Vassallo M, Mayes L, Persing J, Alperovich M. Long-term neurocognitive and behavioral outcomes in patients with non-syndromic craniosynostosis. Child's Nervous System 2025, 41: 233. PMID: 40659876, DOI: 10.1007/s00381-025-06888-0.Peer-Reviewed Original ResearchConceptsNon-syndromic craniosynostosisBehavioral testsCraniofacial plastic surgeonsGeneral populationNeurocognitive testsYears of ageSRS-2Corrective surgeryResultsThirty-twoModerate-severeAutism-related behaviorsCounseling parentsCraniosynostosisPatientsPlastic surgeonsPrevalence of ADHDDiagnosis of autismResultsThirty-two participantsInfantsEarly screeningMean scoreOperative recordsSurgeryADHD indexBehavior of patients
2024
Clinician–caregiver informant discrepancy is associated with sex, diagnosis age, and intervention use among autistic children
Azu M, Han G, Wolf J, Naples A, Chawarska K, Dawson G, Bernier R, Jeste S, Dziura J, Webb S, Sugar C, Shic F, McPartland J. Clinician–caregiver informant discrepancy is associated with sex, diagnosis age, and intervention use among autistic children. Autism 2024, 29: 614-626. PMID: 39344965, PMCID: PMC11906266, DOI: 10.1177/13623613241279999.Peer-Reviewed Original ResearchAutism-related behaviorsAutism featuresClinician ratingsParent ratingsInformant discrepanciesCaregiver ratingsCaregiver reportsAutism diagnosisAutistic childrenChild sexAutismCaregiver perceptionsIntervention useClinicians' perceptionsAssociated with sexCaregiversChildrenDiagnosis ageCliniciansOlder ageInterventionPerceptionGirlsSexAge
2019
Network Analysis of Behaviors in the Depression and Autism Realms: Inter-Relationships and Clinical Implications
Montazeri F, de Bildt A, Dekker V, Anderson GM. Network Analysis of Behaviors in the Depression and Autism Realms: Inter-Relationships and Clinical Implications. Journal Of Autism And Developmental Disorders 2019, 50: 1580-1595. PMID: 30778821, DOI: 10.1007/s10803-019-03914-4.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderASD groupHigh-functioning individualsSpecific intervention targetsAutism-related behaviorsASD networkSpectrum disorderIntervention targetsAnxiety itemsClinical depressionNetwork of depressionOCDAnxietyDepressionDepression itemsItemsClinical implicationsInsomniaAutismInter-relationshipsItem moduleRestlessnessBehaviorIndividualsDisorders
2018
Brain region-specific disruption of Shank3 in mice reveals a dissociation for cortical and striatal circuits in autism-related behaviors
Bey AL, Wang X, Yan H, Kim N, Passman RL, Yang Y, Cao X, Towers AJ, Hulbert SW, Duffney LJ, Gaidis E, Rodriguiz RM, Wetsel WC, Yin HH, Jiang YH. Brain region-specific disruption of Shank3 in mice reveals a dissociation for cortical and striatal circuits in autism-related behaviors. Translational Psychiatry 2018, 8: 94. PMID: 29700290, PMCID: PMC5919902, DOI: 10.1038/s41398-018-0142-6.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAutism Spectrum DisorderBehavior, AnimalCorpus StriatumDisease Models, AnimalExcitatory Postsynaptic PotentialsHippocampusHomer Scaffolding ProteinsMice, KnockoutMicrofilament ProteinsNerve Tissue ProteinsNeuronsPhenotypeProsencephalonReceptors, Dopamine D1Receptors, Dopamine D2Receptors, N-Methyl-D-AspartateSocial BehaviorSynapsesConceptsDeletion of Shank3Brain regionsAutism-related behaviorsWhole-cell patch recordingsGluN2B-containing NMDARsShank3 mutant miceHomer1b/cRegion-specific disruptionRespective brain regionsNeural circuit mechanismsSpecific brain regionsASD-like behaviorsStriatal lossStriatal neuronsElectrophysiological findingsExcitatory neuronsHippocampal neuronsCell type-specific rolesInhibitory neuronsASD-related behaviorsStriatal circuitsSHANK3 deletionStriatal D1Excessive groomingPatch recordings
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