2014
Modern Experience with Aggressive Parathyroid Tumors in a High-Volume New England Referral Center
Quinn CE, Healy J, Lebastchi AH, Brown TC, Stein JE, Prasad ML, Callender GG, Carling T, Udelsman R. Modern Experience with Aggressive Parathyroid Tumors in a High-Volume New England Referral Center. Journal Of The American College Of Surgeons 2014, 220: 1054-1062. PMID: 25488353, DOI: 10.1016/j.jamcollsurg.2014.10.007.Peer-Reviewed Original ResearchConceptsParathyroid carcinomaAtypical adenomasReferral centerParathyroid tumorsIntact parathyroid hormone levelsTertiary academic referral centerClinicopathologic tumor characteristicsParathyroid carcinoma patientsParathyroid hormone levelsAcademic referral centerAtypical parathyroid adenomaLoss of parafibrominHypercalcemic crisisProspective databaseIntraoperative variablesPathologic variablesRare malignancySurgical treatmentCarcinoma patientsClinical presentationSerum calciumTumor characteristicsParathyroid adenomaPostoperative managementTumor size
2011
Parathyroid Four‐Dimensional Computed Tomography: Evaluation of Radiation Dose Exposure During Preoperative Localization of Parathyroid Tumors in Primary Hyperparathyroidism
Mahajan A, Starker LF, Ghita M, Udelsman R, Brink JA, Carling T. Parathyroid Four‐Dimensional Computed Tomography: Evaluation of Radiation Dose Exposure During Preoperative Localization of Parathyroid Tumors in Primary Hyperparathyroidism. World Journal Of Surgery 2011, 36: 1335-1339. PMID: 22146947, DOI: 10.1007/s00268-011-1365-3.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overChildChild, PreschoolFemaleFour-Dimensional Computed TomographyHumansHyperparathyroidism, PrimaryInfantInfant, NewbornMaleMiddle AgedParathyroid NeoplasmsParathyroidectomyPreoperative CareRadiation DosageRadiopharmaceuticalsTechnetium Tc 99m SestamibiTomography, Emission-Computed, Single-PhotonYoung AdultConceptsPrimary hyperparathyroidismFour-dimensional computed tomographyParathyroid tumorsPreoperative localizationThyroid cancerComputed tomographyRadiation doseRadiation exposureSingle-photon emission CTMCi of technetiumSex-dependent risk factorsYear old womanThyroid radiation doseRadiation dose exposurePreoperative imaging modalitiesImaging Performance AssessmentPhoton emission CTCT radiation doseRow CT scannerDetector-row CT scannerPHPT patientsInvasive parathyroidectomyRisk factorsOlder womenBackground radiation exposure
2010
4D Parathyroid CT as the Initial Localization Study for Patients with De Novo Primary Hyperparathyroidism
Starker LF, Mahajan A, Björklund P, Sze G, Udelsman R, Carling T. 4D Parathyroid CT as the Initial Localization Study for Patients with De Novo Primary Hyperparathyroidism. Annals Of Surgical Oncology 2010, 18: 1723-1728. PMID: 21184187, DOI: 10.1245/s10434-010-1507-0.Peer-Reviewed Original ResearchConceptsPrimary hyperparathyroidismMultiglandular diseaseParathyroid tumorsIntraoperative parathyroid hormone measurementParathyroid hormone measurementDe novo patientsMajority of patientsPreferred imaging modalityFour-dimensional computed tomographyIntact PTHInvasive parathyroidectomyConsecutive patientsNovo patientsPathologic findingsParathyroid lesionsComputed tomographyHormone measurementsPatientsCorrect quadrantBiochemical measurementsLocalization studiesTumorsS-CaImaging modalitiesHyperparathyroidism
2006
Surveillance for Early Detection of Aggressive Parathyroid Disease: Carcinoma and Atypical Adenoma in Familial Isolated Hyperparathyroidism Associated With a Germline HRPT2 Mutation1*
Kelly TG, Shattuck TM, Reyes‐Mugica M, Stewart AF, Simonds WF, Udelsman R, Arnold A, Carpenter TO. Surveillance for Early Detection of Aggressive Parathyroid Disease: Carcinoma and Atypical Adenoma in Familial Isolated Hyperparathyroidism Associated With a Germline HRPT2 Mutation1*. Journal Of Bone And Mineral Research 2006, 21: 1666-1671. PMID: 16995822, DOI: 10.1359/jbmr.060702.Peer-Reviewed Original ResearchConceptsGermline HRPT2 mutationsHRPT2 mutationsPrimary hyperparathyroidismEarly detectionParathyroid tumorsFamilial hyperparathyroid syndromesAggressive histological featuresSpecific surveillance strategiesMalignant parathyroid tumorsGenetic screeningLeukocyte DNA analysisMutations of HRPT2FIHP familiesHyperparathyroidism AssociatedParathyroid statusRecurrent diseaseClassic tumor suppressor geneBiochemical surveillanceLeft neckRare causeAggressive featuresInitial tumorParathyroid diseaseSurgical extirpationPatients 7
1997
Clear cell neoplasms of the endocrine system and thymus.
Wick M, Ritter J, Humphrey P, Nappi O. Clear cell neoplasms of the endocrine system and thymus. Seminars In Diagnostic Pathology 1997, 14: 183-202. PMID: 9279975.Peer-Reviewed Original ResearchConceptsEndocrine systemClear cell tumorsClear cell neoplasmsPancreatic endocrine neoplasmsThymic malignanciesThymic lesionsRare lesionsCell tumorsEndocrine tumorsAdrenocortical proliferationParathyroid tumorsCell neoplasmsDifferential diagnosisPituitary adenomasSurgical pathologistsEndocrine neoplasmsSimilar lesionsNeoplasmsLesionsTumorsUltrastructural featuresLymphoid differentiationThymusDiagnosisGerm cells
1991
Allelic loss on chromosome 11 in hereditary and sporadic tumors related to familial multiple endocrine neoplasia type 1.
Bale A, Norton J, Wong E, Fryburg J, Maton P, Oldfield E, Streeten E, Aurbach G, Brandi M, Friedman E. Allelic loss on chromosome 11 in hereditary and sporadic tumors related to familial multiple endocrine neoplasia type 1. Cancer Research 1991, 51: 1154-7. PMID: 1671755.Peer-Reviewed Original ResearchConceptsFamilial multiple endocrine neoplasia type 1Multiple endocrine neoplasia type 1Anterior pituitary tumorsPancreatic islet tumorsIslet tumorsPituitary tumorsAllelic lossType 1Autosomal dominant disorderMalignant gastrinomaBronchial carcinoidParathyroid glandsParathyroid tumorsAnterior pituitaryLoss of heterozygosityTumorsPancreatic isletsSporadic tumorsDominant disorderMEN1 genePatientsRestriction fragment length polymorphismFragment length polymorphismHomozygous inactivationInformative restriction fragment length polymorphisms
1989
Clonality of Parathyroid Tumors in Familial Multiple Endocrine Neoplasia Type 1
Friedman E, Sakaguchi K, Bale A, Falchetti A, Streeten E, Zimering M, Weinstein L, McBride W, Nakamura Y, Brandi M, Norton J, Aurbach G, Spiegel A, Marx S. Clonality of Parathyroid Tumors in Familial Multiple Endocrine Neoplasia Type 1. New England Journal Of Medicine 1989, 321: 213-218. PMID: 2568586, DOI: 10.1056/nejm198907273210402.Peer-Reviewed Original Research
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