2016
The Cervical Vestibular-Evoked Myogenic Potentials (cVEMPs) Recorded Along the Sternocleidomastoid Muscles During Head Rotation and Flexion in Normal Human Subjects
Ashford A, Huang J, Zhang C, Wei W, Mustain W, Eby T, Zhu H, Zhou W. The Cervical Vestibular-Evoked Myogenic Potentials (cVEMPs) Recorded Along the Sternocleidomastoid Muscles During Head Rotation and Flexion in Normal Human Subjects. Journal Of The Association For Research In Otolaryngology 2016, 17: 303-311. PMID: 27105980, PMCID: PMC4940286, DOI: 10.1007/s10162-016-0566-8.Peer-Reviewed Original ResearchConceptsCervical Vestibular Evoked Myogenic PotentialsSternocleidomastoid muscleMyogenic potentialsHead flexionTonic levelsVestibular-evoked myogenic potentialsHead rotationLeft sternocleidomastoid muscleHealthy adult subjectsNormal human subjectsSternal headVestibular functionReflex pathwaysContralateral earAdult subjectsSensory componentFlexionTone burstsSurface electrodesHuman subjectsRecording sitesMotor componentsMusclePresent studySubjects
2012
Frequency Tuning of the Cervical Vestibular-Evoked Myogenic Potential (cVEMP) Recorded from Multiple Sites along the Sternocleidomastoid Muscle in Normal Human Subjects
Wei W, Jeffcoat B, Mustain W, Zhu H, Eby T, Zhou W. Frequency Tuning of the Cervical Vestibular-Evoked Myogenic Potential (cVEMP) Recorded from Multiple Sites along the Sternocleidomastoid Muscle in Normal Human Subjects. Journal Of The Association For Research In Otolaryngology 2012, 14: 37-47. PMID: 23183876, PMCID: PMC3540270, DOI: 10.1007/s10162-012-0360-1.Peer-Reviewed Original ResearchConceptsCervical Vestibular Evoked Myogenic PotentialsSternocleidomastoid muscleMyogenic potentialsTonic levelsVestibular-evoked myogenic potentialsNormal human subjectsTuning curvesCVEMP responsesVEMP testFrequency tuning propertiesVestibular deficitsVestibular functionLower quarterLow sound intensities
2008
Anesthetic effects on regional CBF, BOLD, and the coupling between task‐induced changes in CBF and BOLD: An fMRI study in normal human subjects
Qiu M, Ramani R, Swetye M, Rajeevan N, Constable RT. Anesthetic effects on regional CBF, BOLD, and the coupling between task‐induced changes in CBF and BOLD: An fMRI study in normal human subjects. Magnetic Resonance In Medicine 2008, 60: 987-996. PMID: 18816821, PMCID: PMC2716171, DOI: 10.1002/mrm.21759.Peer-Reviewed Original ResearchConceptsCerebral blood flowLow-dose sevofluraneRegional cerebral blood flowTask-induced changesBaseline cerebral blood flowBlood oxygen level-dependent (BOLD) signalAbsence of anesthesiaHealthy human subjectsHuman subjectsNormal human subjectsLevel-dependent signalFunctional MR imagingVascular measuresAnesthetic agentsBlood flowAnesthetic effectSevofluraneFunctional MRI dataAnesthesia conditionsAnesthesiaMR imagingAuditory regionsOxidative metabolismAuditory stimuliFMRI study
1994
BOLD MRI monitoring of changes in cerebral perfusion induced by acetazolamide and hypercarbia in the rat
Graham G, Zhong J, Petroff O, Constable R, Prichard J, Gore J. BOLD MRI monitoring of changes in cerebral perfusion induced by acetazolamide and hypercarbia in the rat. Magnetic Resonance In Medicine 1994, 31: 557-560. PMID: 8015411, DOI: 10.1002/mrm.1910310514.Peer-Reviewed Original ResearchConceptsApparent diffusion coefficientNormal human subjectsMRI changesCerebral perfusionCerebrovascular reserveCerebrovascular diseaseAnatomic mappingRatsMRI monitoringSignificant decreaseHuman subjectsMRI methodsMRI signalHypercarbiaPatientsInhalationPerfusionReactivity patternsAcetazolamideDiseaseAdministrationMetabolic Effects of rhIGF-1 in Normal Human Subjects
Rennert NJ, Boulware SD, Kerr D, Caprio S, Tamborlane WV, Sherwin RS. Metabolic Effects of rhIGF-1 in Normal Human Subjects. Advances In Experimental Medicine And Biology 1994, 343: 311-318. PMID: 8184741, DOI: 10.1007/978-1-4615-2988-0_30.Peer-Reviewed Original ResearchConceptsRhIGF-1Hepatic glucose productionIGF-1Free fatty acidsGlucose productionGlucose uptakeEuglycemic clamp techniqueHuman IGF-1Normal human subjectsSpite of maintenanceSustained euglycemiaMetabolic effectsFFA levelsHypoglycemic effectClamp techniqueMetabolic actionsProfound reductionInsulinHypoglycemic hormoneFat cellsRatsComparable stimulationProtein breakdownSimilar extentEuglycemia
1989
Intravenous physostigmine increases cerebrospinal fluid neuropeptide-Y
Berrettini W, Garrick N, Nurnberger J, Simmons-Alling S, Gelernter J, Gold P, Rubinow D, Murphy D. Intravenous physostigmine increases cerebrospinal fluid neuropeptide-Y. Biological Psychiatry 1989, 26: 623-630. PMID: 2790099, DOI: 10.1016/0006-3223(89)90087-5.Peer-Reviewed Original ResearchConceptsIntravenous infusionMicrograms/Central nervous system neurotransmittersAcute pharmacological challengePharmacological challenge paradigmsAcute intravenous infusionSerial CSF samplesDose-time interactionUseful clinical toolNormal human subjectsCholinergic agonist physostigmineCerebrospinal fluid neuropeptidesCSF NPYPhysostigmine infusionStimulus-induced responsesIntravenous physostigmineCSF levelsCSF cathetersCSF neuropeptidesNeuropeptide changesPharmacological challengeCSF samplesClinical toolRhesus monkeysPhysostigmine
1986
Antigen reactive memory T cells are defined by Ta1.
Hafler DA, Fox DA, Benjamin D, Weiner HL. Antigen reactive memory T cells are defined by Ta1. The Journal Of Immunology 1986, 137: 414-8. PMID: 3013990, DOI: 10.4049/jimmunol.137.2.414.Peer-Reviewed Original ResearchConceptsT cellsReactive memory T cellsPeripheral blood T cellsAutologous mixed lymphocyte responseHuman peripheral blood T cellsMemory T cellsMixed lymphocyte responseBlood T cellsPresence of PWMT cell clonesEnhanced proliferative responseTA1 cellsActivated T cellsNormal human subjectsT cell linesT memory cellsSuppressor cellsLymphocyte responsesAnamnestic responseMitogen PHAPeripheral bloodLymphocyte populationsIL-2Tetanus toxoidT lymphocytes
1983
Naloxone augments electrophysiological signs of selective attention in man
Arnsten A, Segal D, Neville H, Hillyard S, Janowsky D, Judd L, Bloom F. Naloxone augments electrophysiological signs of selective attention in man. Nature 1983, 304: 725-727. PMID: 6888538, DOI: 10.1038/304725a0.Peer-Reviewed Original ResearchConceptsEndogenous opioid systemOpioid systemSelective attentionOpiate antagonist naloxoneSelective information processingNormal human subjectsAntagonist naloxoneOpiate antagonistElectrophysiological signsAuditory attentionOpioid roleElectrophysiological measuresGeneral arousalElectrophysiological evidenceInformation processingBehavioral functionsNaloxoneHuman subjectsSource of stimulusMenPrevious researchArousalAttentionAntagonist
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