2020
Predictors of successful randomized phase III studies in the treatment metastatic renal cell carcinoma: A meta-analysis.
Lin J, Zhong X, Galsky M, Oh W, Tsao C. Predictors of successful randomized phase III studies in the treatment metastatic renal cell carcinoma: A meta-analysis. Journal Of Clinical Oncology 2020, 38: e17105-e17105. DOI: 10.1200/jco.2020.38.15_suppl.e17105.Peer-Reviewed Original ResearchMetastatic renal cell carcinomaRenal cell carcinomaPrimary endpointCell carcinomaRandomized phase III studyNegative endpointsFactors associated with PEPhase III studyAdvanced kidney cancerBaseline patient characteristicsPhase III therapeutic trialsAssociated with PETrial designClinical characteristic variablesMultivariate logistic regressionClinical trial designIII studiesBaseline patientSubgroup analysisKidney cancerTherapeutic trialsPatient characteristicsTherapy studiesPositive endpointsMeta-analysis
2016
A major miss in prognostication after cardiac arrest: Burst suppression and brain healing
Becker D, Schiff N, Becker L, Holmes M, Fins J, Horowitz J, Devinsky O. A major miss in prognostication after cardiac arrest: Burst suppression and brain healing. Epilepsy & Behavior Reports 2016, 7: 1-5. PMID: 28053858, PMCID: PMC5198796, DOI: 10.1016/j.ebcr.2016.09.004.Peer-Reviewed Original ResearchCardiac arrestBurst suppressionTherapeutic hypothermiaLoss of brainstem reflexesMechanisms of therapeutic hypothermiaOut-of-hospital cardiac arrestAbsent motor responseStatus epilepticusBrainstem reflexesNeuronal cell deathFunctional capacityStandard criteriaCell deathArrestNegative endpointsHypothermiaMotor responseEnd-of-life decisionsBrain healingEnd-of-lifeEpilepticusSuppressionEndpoint
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