2023
73 Identification of 24-Month Cognitive Trajectories Among Clinical High Risk for Psychosis (CHR-P) Using Latent Class Mixture Modeling
Guest R, Addington J, Bearden C, Cadenhead K, Cornblatt B, Mathalon D, Perkins D, Tsuang M, Woods S, Cannon T, Keshavan M, Stone W, Walker E. 73 Identification of 24-Month Cognitive Trajectories Among Clinical High Risk for Psychosis (CHR-P) Using Latent Class Mixture Modeling. Journal Of The International Neuropsychological Society 2023, 29: 857-858. DOI: 10.1017/s1355617723010597.Peer-Reviewed Original ResearchMATRICS Consensus Cognitive BatterySpeed of processingVerbal learningCognitive batteryCognitive trajectoriesCognitive deficitsWide Range Achievement TestDomain-specific deficitsConsensus Cognitive BatteryWechsler Abbreviated ScalePre-morbid IQHigher cognitive skillsFull Scale IQLower premorbid IQAge-based normsMild cognitive deficitsClinical high riskMCCB domainsCognitive remediationMemory domainCognitive skillsGeneral cognitionReading subtestCognitive performanceNorth American Prodromal Longitudinal Study
2018
Persistence of abnormalities in white matter in children with type 1 diabetes
Fox LA, Hershey T, Mauras N, Arbeláez AM, Tamborlane WV, Buckingham B, Tsalikian E, Englert K, Raman M, Jo B, Shen H, Reiss A, Mazaika P, for the Diabetes Research in Children Network (DirecNet). Persistence of abnormalities in white matter in children with type 1 diabetes. Diabetologia 2018, 61: 1538-1547. PMID: 29654376, PMCID: PMC5991628, DOI: 10.1007/s00125-018-4610-6.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsBiomarkersBlood GlucoseCase-Control StudiesChildChild DevelopmentChild, PreschoolCognitive DysfunctionDiabetes Mellitus, Type 1Diffusion Tensor ImagingFemaleGlycated HemoglobinHumansLeukoencephalopathiesLongitudinal StudiesMagnetic Resonance ImagingMalePrognosisRisk FactorsTime FactorsUnited StatesConceptsType 1 diabetesNon-diabetic childrenWhite matter microstructureWhite matterAltered white matter developmentContinuous glucose monitoring (CGM) profilesFractional anisotropyConclusions/interpretationThese resultsPersistence of abnormalitiesLongitudinal observational studyWhite matter growthYoung childrenWhite matter developmentMild cognitive deficitsHigher fractional anisotropyDiabetes groupClinical centersMethodsOne hundredObservational studyDiabetesInterpretationThese resultsCognitive deficitsHyperglycaemiaDiabetes researchAdverse effects
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