2008
Sodium channel activity modulates multiple functions in microglia
Black JA, Liu S, Waxman SG. Sodium channel activity modulates multiple functions in microglia. Glia 2008, 57: 1072-1081. PMID: 19115387, DOI: 10.1002/glia.20830.Peer-Reviewed Original ResearchMeSH KeywordsAdenosine TriphosphateAnimalsAnimals, NewbornBrainCell MovementCell ProliferationCells, CulturedCoculture TechniquesCytokinesGliosisInflammation MediatorsMicrogliaNAV1.1 Voltage-Gated Sodium ChannelNAV1.5 Voltage-Gated Sodium ChannelNAV1.6 Voltage-Gated Sodium ChannelNerve Tissue ProteinsPhagocytosisPhenytoinRatsRats, Sprague-DawleySodium Channel BlockersSodium ChannelsTetrodotoxinConceptsIL-1 betaIL-1 alphaSodium channelsTNF-alphaPhagocytic activitySodium channel blockadeSodium channel Nav1.1Central nervous systemVoltage-gated sodium channelsSodium channel activitySodium channel isoformsActivated microgliaIL-10IL-6MCP-1Microglial migrationChannel Nav1.1Cultured microgliaIL-2IL-4MicroM TTXChannel blockadeMed miceMicrogliaTissue insult
1996
Action potential-like responses in B 104 cells with low Na+ channel densities
Gu X, Waxman S. Action potential-like responses in B 104 cells with low Na+ channel densities. Brain Research 1996, 735: 50-58. PMID: 8905169, DOI: 10.1016/0006-8993(96)00604-x.Peer-Reviewed Original ResearchConceptsAction potential-like responsesB104 cellsWhole-cell patch-clamp methodB104 neuroblastoma cellsPA/pFCurrent-clamp modeSteady-state inactivationAction potential generationPatch-clamp methodMicroM TTXNeuroblastoma cellsPrepulse potentialPotential generationResponse amplitudeCellsResponseStimuli
1987
Voltage‐dependent conductances of solitary ganglion cells dissociated from the rat retina.
Lipton S, Tauck D. Voltage‐dependent conductances of solitary ganglion cells dissociated from the rat retina. The Journal Of Physiology 1987, 385: 361-391. PMID: 2443669, PMCID: PMC1192350, DOI: 10.1113/jphysiol.1987.sp016497.Peer-Reviewed Original ResearchConceptsWhole-cell recordingsRetinal ganglion cellsGanglion cellsPatch pipetteMicroM TTXRat retinaAction potentialsMM TEASlow action potentialsPatch-clamp recordingsSingle-channel recordingsCentral mammalian neuronesConventional intracellular electrodesCurrent-clamp conditionsWhole-cell currentsVoltage-clamp experimentsIntracellular recordingsVoltage-clamp analysisPharmacological agentsExtracellular Ca2Inactivation time constantsMicroM Cd2Conventional intracellularElectrophysiological propertiesFast spikes
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply