2023
A wider and deeper peptide-binding groove for the class I molecules from B15 compared to B19 chickens correlates with relative resistance to Marek’s disease
Han L, Wu S, Zhang T, Peng W, Zhao M, Yue C, Wen W, Cai W, Li M, Wallny H, Avila D, Mwangi W, Nair V, Ternette N, Guo Y, Zhao Y, Chai Y, Qi J, Liang H, Gao G, Kaufman J, Liu W. A wider and deeper peptide-binding groove for the class I molecules from B15 compared to B19 chickens correlates with relative resistance to Marek’s disease. The Journal Of Immunology 2023, 210: 668-680. PMID: 36695776, PMCID: PMC7614295, DOI: 10.4049/jimmunol.2200211.Peer-Reviewed Original ResearchConceptsPeptide-binding grooveResistance to MDMarek's diseaseResistance to Marek's diseaseGas phase sequencingClass I genesPeptide motifsI geneGeneralist allelesChicken MHCImportant pathogensChicken linesMD resistanceCell surfaceAmino acidsB19 chickensExpression levelsChickenOncogenic herpesvirusX-ray crystallographyClass I moleculesPeptideStronger bindingI moleculesMotif
2004
9 Genetic resistance to Marek's disease
Bumstead N, Kaufman J. 9 Genetic resistance to Marek's disease. 2004, 112-vi. DOI: 10.1016/b978-012088379-0/50013-x.Peer-Reviewed Original ResearchChicken major histocompatibility complexGenome mappingMajor histocompatibility complexMD resistance genesChicken genome sequenceMD resistanceMarek's diseaseExpressed class I moleculeInbred chicken linesMajor histocompatibility complex haplotypeGenome sequencePositional cloningGene interactionsResistance genesDNA arraysGenetic mechanismsChicken linesProteomic technologiesGenesIndividual chickensHaplotypesChickenHistocompatibility complexClass I moleculesClass II molecules
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply