2012
A renaissance in therapeutic options for pancreatic neuroendocrine tumors.
Kunz PL. A renaissance in therapeutic options for pancreatic neuroendocrine tumors. American Society Of Clinical Oncology Educational Book 2012, 271-4. PMID: 24451747, DOI: 10.14694/edbook_am.2012.32.136.Peer-Reviewed Original ResearchProgression-free survivalPancreatic neuroendocrine tumorsNeuroendocrine tumorsTherapeutic optionsRandomized placebo-controlled studyPlacebo-controlled studyNovel therapeutic optionsChemotherapy backboneLocoregional diseaseAdvanced diseaseBiologic therapySurgical resectionSomatostatin analoguesClinical trialsDrug AdministrationU.S. FoodAntiproliferative agentsTumorsDiseaseFuture studiesResectionEverolimusSunitinibPatientsOptions
2010
Cytotoxic and antioxidant effects of methoxylated stilbene analogues on HepG2 hepatoma and Chang liver cells: Implications for structure activity relationship
Hasiah A, Ghazali A, Weber J, Velu S, Thomas N, Inayat Hussain S. Cytotoxic and antioxidant effects of methoxylated stilbene analogues on HepG2 hepatoma and Chang liver cells: Implications for structure activity relationship. Human & Experimental Toxicology 2010, 30: 138-144. PMID: 20385705, DOI: 10.1177/0960327110368739.Peer-Reviewed Original ResearchConceptsChang liver cellsHepG2 hepatomaTotal antioxidant activityLiver cellsCytotoxic effectsAntioxidant activityFerric Reducing Antioxidant Power AssayChemopreventive activityAntioxidant effectsAntioxidant power assayStilbene analoguesSelective antiproliferative agentsStructure-activity relationship studiesHepG2 cellsAntiproliferative agentsHighest antioxidant activityPower assayHepatomaActivity relationship studiesStructural activity relationshipCytotoxicCellsActivity relationshipsRelationship studiesStructure-activity relationships
2003
The proapoptotic benzodiazepine Bz-423 affects the growth and survival of malignant B cells.
Boitano A, Ellman JA, Glick GD, Opipari AW. The proapoptotic benzodiazepine Bz-423 affects the growth and survival of malignant B cells. Cancer Research 2003, 63: 6870-6. PMID: 14583485.Peer-Reviewed Original ResearchConceptsB cell linesSystemic lupus erythematosusMalignant B-cell linesMalignant B cellsPeripheral benzodiazepine receptorReactive oxygen species levelsEBV statusLupus erythematosusLymphoproliferative diseaseAntineoplastic therapyOxygen species levelsBurkitt's lymphomaAnimal modelsBenzodiazepine receptorsClinical developmentB cellsPotent antiproliferative agentBz-423Phase arrestBcl-2Expression levelsLymphomaAntiproliferative agentsCell deathDisease
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