2023
Lung endothelium, tau, and amyloids in health and disease
Balczon R, Lin M, Voth S, Nelson A, Schupp J, Wagener B, Pittet J, Stevens T. Lung endothelium, tau, and amyloids in health and disease. Physiological Reviews 2023, 104: 533-587. PMID: 37561137, PMCID: PMC11281824, DOI: 10.1152/physrev.00006.2023.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsEnd-organ dysfunctionLung endotheliumLower respiratory tract infectionsRespiratory tract infectionsAlveolar-capillary barrierLung capillary endotheliumTract infectionsImmune responseNeurocognitive dysfunctionBarrier integrityProtein tauLung capillariesInfectionCapillary endotheliumDysfunctionEpithelial cellsEndotheliumTau variantsVascular nicheTauHost-pathogen interactionsType ICytotoxic activityCytotoxicAmyloid variants
2017
The cationic small molecule GW4869 is cytotoxic to high phosphatidylserine‐expressing myeloma cells
Vuckovic S, Vandyke K, Rickards DA, Winter P, Brown SHJ, Mitchell TW, Liu J, Lu J, Askenase PW, Yuriev E, Capuano B, Ramsland PA, Hill GR, Zannettino ACW, Hutchinson AT. The cationic small molecule GW4869 is cytotoxic to high phosphatidylserine‐expressing myeloma cells. British Journal Of Haematology 2017, 177: 423-440. PMID: 28211573, DOI: 10.1111/bjh.14561.Peer-Reviewed Original ResearchConceptsMyeloma cell linesMyeloma cellsMyeloma plasma cellsCell linesPlasma cellsPrimary myeloma samplesMalignant cellsMyeloma samplesGW4869Surface phosphatidylserine exposurePhosphatidylserine expressionPhosphatidylserine exposureCell surface phosphatidylserine exposureCellsBiochemical analysisCytotoxicSmall cationic moleculesIntracellular sidePhosphatidylserineCancerCell membraneSmall moleculesBrefeldin A
2010
Cytotoxic and antioxidant effects of methoxylated stilbene analogues on HepG2 hepatoma and Chang liver cells: Implications for structure activity relationship
Hasiah A, Ghazali A, Weber J, Velu S, Thomas N, Inayat Hussain S. Cytotoxic and antioxidant effects of methoxylated stilbene analogues on HepG2 hepatoma and Chang liver cells: Implications for structure activity relationship. Human & Experimental Toxicology 2010, 30: 138-144. PMID: 20385705, DOI: 10.1177/0960327110368739.Peer-Reviewed Original ResearchConceptsChang liver cellsHepG2 hepatomaTotal antioxidant activityLiver cellsCytotoxic effectsAntioxidant activityFerric Reducing Antioxidant Power AssayChemopreventive activityAntioxidant effectsAntioxidant power assayStilbene analoguesSelective antiproliferative agentsStructure-activity relationship studiesHepG2 cellsAntiproliferative agentsHighest antioxidant activityPower assayHepatomaActivity relationship studiesStructural activity relationshipCytotoxicCellsActivity relationshipsRelationship studiesStructure-activity relationships
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply