2008
Development of Immunogenic Tumor-Loaded Dendritic Cells Through Physical Perturbation and Apoptotic Cell Loading
Shen X, Berger CL, Tigelaar R, Edelson RL. Development of Immunogenic Tumor-Loaded Dendritic Cells Through Physical Perturbation and Apoptotic Cell Loading. Immunological Investigations 2008, 37: 798-821. PMID: 18991097, DOI: 10.1080/08820130802403358.Peer-Reviewed Original ResearchMeSH KeywordsAntigen PresentationAntigens, CDAntigens, NeoplasmApoptosisB7-1 AntigenCancer VaccinesCD8-Positive T-LymphocytesCell DifferentiationCell Line, TumorCytotoxicity, ImmunologicDendritic CellsHumansImmunoglobulinsLymphocyte ActivationLymphoma, T-CellMechanotransduction, CellularMembrane GlycoproteinsMonocytesPerforinReceptors, CCR7Silicon DioxideConceptsT cellsDendritic cellsAllogeneic T cell proliferationCD8 T cellsLevels of perforinChemokine receptor CCR7T cell proliferationApoptotic tumor cellsUniverse of antigensDC vaccinesImmunogenic tumorsImmature DCsReceptor CCR7TNF-alphaPassage of leukocytesIFN-gammaHuman monocytesMonocytesTumor cellsPotent inductionCell apoptosisPhenotypic conversionCell proliferationApoptotic cellsCells induces
2006
Innate immunity defects in Hermansky-Pudlak type 2 syndrome
Fontana S, Parolini S, Vermi W, Booth S, Gallo F, Donini M, Benassi M, Gentili F, Ferrari D, Notarangelo L, Cavadini P, Marcenaro E, Dusi S, Cassatella M, Facchetti F, Griffiths G, Moretta A, Notarangelo L, Badolato R. Innate immunity defects in Hermansky-Pudlak type 2 syndrome. Blood 2006, 107: 4857-4864. PMID: 16507770, DOI: 10.1182/blood-2005-11-4398.Peer-Reviewed Original ResearchMeSH KeywordsAdaptor Protein Complex 3Adaptor Protein Complex beta SubunitsAdultAntigens, CDChildChild, PreschoolFemaleGene Expression RegulationHermanski-Pudlak SyndromeHumansImmunity, CellularImmunity, InnateImmunologic Deficiency SyndromesInfantKiller Cells, NaturalLeukocyte ElastaseMaleNeutrophilsPlatelet Membrane GlycoproteinsTetraspanin 30trans-Golgi NetworkConceptsAdaptor protein 3Hermansky-PudlakHermansky-Pudlak syndrome type 2Type 2 syndromeTrans-GolgiCargo proteinsBeta3A subunitAutosomal recessive diseaseDefects of innate immunityPlasma membraneNatural killerNK cellsInnate immunityInnate immune defectsAnalysis of neutrophilsRecessive diseaseIL-2-activated NK cellsPartial albinismLevels of perforinPathogenesis of immunodeficiencyUnstimulated NK cellsProtein 3Cytolitic activityImmune defectsNeutrophil function
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