2016
Cellular softening mediates leukocyte demargination and trafficking, thereby increasing clinical blood counts
Fay ME, Myers DR, Kumar A, Turbyfield CT, Byler R, Crawford K, Mannino RG, Laohapant A, Tyburski EA, Sakurai Y, Rosenbluth MJ, Switz NA, Sulchek TA, Graham MD, Lam WA. Cellular softening mediates leukocyte demargination and trafficking, thereby increasing clinical blood counts. Proceedings Of The National Academy Of Sciences Of The United States Of America 2016, 113: 1987-1992. PMID: 26858400, PMCID: PMC4776450, DOI: 10.1073/pnas.1508920113.Peer-Reviewed Original ResearchConceptsHematopoietic stem cell mobilizationEffects of glucocorticoidsStem cell mobilizationWhite blood cellsHealthy human subjectsInnate immune systemProportion of granulocytesCatecholamine exposureBlood countGranulocyte countInflammatory processCell mobilizationLeukocyte traffickingDemarginationVascular wallImmune systemLeukocyte stiffnessGlucocorticoidsCatecholamine hormonesBlood cellsCapillary bedHuman subjectsUnderlying mechanismLarge vesselsCount
2014
Severe falciparum malaria associated with massive pulmonary embolism
Musoke C, Ssendikadiwa C, Babua C, Schwartz JI. Severe falciparum malaria associated with massive pulmonary embolism. Annals Of African Medicine 2014, 13: 47-49. PMID: 24521579, DOI: 10.4103/1596-3519.126952.Peer-Reviewed Original Research
2011
Impact of Lesion Length and Vessel Size on Clinical Outcomes After Percutaneous Coronary Intervention With Everolimus- Versus Paclitaxel-Eluting Stents Pooled Analysis From the SPIRIT (Clinical Evaluation of the XIENCE V Everolimus Eluting Coronary Stent System) and COMPARE (Second-generation everolimus-eluting and paclitaxel-eluting stents in real-life practice) Randomized Trials
Claessen BE, Smits PC, Kereiakes DJ, Parise H, Fahy M, Kedhi E, Serruys PW, Lansky AJ, Cristea E, Sudhir K, Sood P, Simonton CA, Stone GW. Impact of Lesion Length and Vessel Size on Clinical Outcomes After Percutaneous Coronary Intervention With Everolimus- Versus Paclitaxel-Eluting Stents Pooled Analysis From the SPIRIT (Clinical Evaluation of the XIENCE V Everolimus Eluting Coronary Stent System) and COMPARE (Second-generation everolimus-eluting and paclitaxel-eluting stents in real-life practice) Randomized Trials. JACC Cardiovascular Interventions 2011, 4: 1209-1215. PMID: 22115661, DOI: 10.1016/j.jcin.2011.07.016.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplasty, Balloon, CoronaryCardiovascular AgentsChi-Square DistributionCoronary AngiographyCoronary StenosisDrug-Eluting StentsEverolimusFemaleHumansKaplan-Meier EstimateMaleMiddle AgedMyocardial InfarctionPaclitaxelPredictive Value of TestsProportional Hazards ModelsProsthesis DesignRandomized Controlled Trials as TopicRisk AssessmentRisk FactorsSeverity of Illness IndexSirolimusThrombosisTime FactorsTreatment OutcomeConceptsMajor adverse cardiac eventsPaclitaxel-eluting stentsReference vessel diameterEverolimus-eluting stentsPercutaneous coronary interventionLong lesionsGroup BLesion lengthMACE rateCoronary interventionSmall vesselsGroup AStent typeShort lesionsAdverse cardiac eventsHigh-risk patientsPatient-level dataLarge vesselsLower ratesCOMPARE trialLesion revascularizationEfficacy outcomesAdverse eventsCardiac eventsIndependent predictors
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