Prophylaxis with rFIXFc Reduces the Frequency and Delays Time to First Spontaneous Bleed Event in Previously Untreated Patients with Hemophilia B: A Post Hoc Analysis of the PUPs B-LONG Trial
Nolan B, Recht M, Rendo P, Falk A, Foster M, Casiano S, Rauch A, Shapiro A. Prophylaxis with rFIXFc Reduces the Frequency and Delays Time to First Spontaneous Bleed Event in Previously Untreated Patients with Hemophilia B: A Post Hoc Analysis of the PUPs B-LONG Trial. Blood 2021, 138: 498. DOI: 10.1182/blood-2021-148765.Peer-Reviewed Original ResearchSpontaneous bleeding eventsEntity's Board of DirectorsBleeding eventsPost Hoc AnalysisHemophilia BYears of agePPX treatmentCSL BehringKaplan-MeierHalf-life recombinant factorTreatment of bleeding eventsPrevention of bleeding eventsHoc AnalysisSmall patient groupsFIX replacement therapyFactor IXKaplan-Meier (KM) survival analysisStandard of careAdvisory CommitteeOD therapyBleeding patternsUntreated patientsPrimary endpointOD regimensProlonged bleeding
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