Regulation of thrombosis and vascular function by protein methionine oxidation
Gu S, Stevens J, Lentz S. Regulation of thrombosis and vascular function by protein methionine oxidation. Blood 2015, 125: 3851-3859. PMID: 25900980, PMCID: PMC4473114, DOI: 10.1182/blood-2015-01-544676.Peer-Reviewed Original ResearchConceptsProtein methionine oxidationMethionine residuesRedox regulation of protein functionRegulation of protein functionOxidation-sensitive methionine residuesMethionine oxidationMethionine sulfoxide reductaseIntracellular redox stateRegulatory domainProtein functionSulfoxide reductaseCellular homeostasisRedox regulationStereospecific enzymesReactive oxygen speciesRegulation of thrombosisSignaling moleculesGene expressionRedox biologyRedox sensorCell adhesionRedox balanceMethionine sulfoxideProteinInflammatory gene expression
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