2025
CryoEM structures of Kv1.2 potassium channels, conducting and non-conducting
Wu Y, Yan Y, Yang Y, Bian S, Rivetta A, Allen K, Sigworth F. CryoEM structures of Kv1.2 potassium channels, conducting and non-conducting. ELife 2025, 12: rp89459. PMID: 39945513, PMCID: PMC11825129, DOI: 10.7554/elife.89459.Peer-Reviewed Original ResearchConceptsIon occupancyIon binding sitesTerminal amineSelectivity filterIon densityLow-resolution structureProtein conformationIonsDetergent micellesPotassium channelsToxin blockVoltage-gated potassium channel Kv1.2Non-conductingStructureVoltage-gated potassium channelsPotassium channel Kv1.2Kv1.2 potassium channelChannel's outer mouthBinding sitesAminesCarbonylCryoEM structures of Kv1.2 potassium channels, conducting and non-conducting
Wu Y, Yan Y, Yang Y, Bian S, Rivetta A, Allen K, Sigworth F. CryoEM structures of Kv1.2 potassium channels, conducting and non-conducting. ELife 2025, 12 DOI: 10.7554/elife.89459.4.Peer-Reviewed Original ResearchIon occupancyIon binding sitesTerminal amineIon densitySelectivity filterLow-resolution structureProtein conformationIonsDetergent micellesPotassium channelsToxin blockVoltage-gated potassium channel Kv1.2Non-conductingStructureVoltage-gated potassium channelsPotassium channel Kv1.2Kv1.2 potassium channelChannel's outer mouthBinding sites
2024
Composition Heterogeneity of Metal Ions Bound at the Oxygen-Evolving Center of Photosystem II in Living Cells
Wang J. Composition Heterogeneity of Metal Ions Bound at the Oxygen-Evolving Center of Photosystem II in Living Cells. Biochemistry 2024, 63: 1963-1968. PMID: 39037205, DOI: 10.1021/acs.biochem.4c00261.Peer-Reviewed Original ResearchConceptsX-ray free-electron lasersStructure of photosystem IIOxygen-evolving centerPhotosystem IICrystal structure of photosystem IIFree-electron laserPhotosystem II dimersPhotosystem ILight-harvesting complexesCryo-electron tomographyMetal ionsPSII samplesCryo-electron microscopyCryo-ETDimeric core complexesCryo-EMMetal ion cofactorsLiving cellsCrystal structureCryo-electronCryo-EM structureMetal-ion occupancyIon occupancySpectroscopic interpretationAsymmetric environment
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply