CryoEM structures of Kv1.2 potassium channels, conducting and non-conducting
Wu Y, Yan Y, Yang Y, Bian S, Rivetta A, Allen K, Sigworth F. CryoEM structures of Kv1.2 potassium channels, conducting and non-conducting. ELife 2025, 12: rp89459. PMID: 39945513, PMCID: PMC11825129, DOI: 10.7554/elife.89459.Peer-Reviewed Original ResearchConceptsIon occupancyIon binding sitesTerminal amineSelectivity filterIon densityLow-resolution structureProtein conformationIonsDetergent micellesPotassium channelsToxin blockVoltage-gated potassium channel Kv1.2Non-conductingStructureVoltage-gated potassium channelsPotassium channel Kv1.2Kv1.2 potassium channelChannel's outer mouthBinding sitesAminesCarbonylCryoEM structures of Kv1.2 potassium channels, conducting and non-conducting
Wu Y, Yan Y, Yang Y, Bian S, Rivetta A, Allen K, Sigworth F. CryoEM structures of Kv1.2 potassium channels, conducting and non-conducting. ELife 2025, 12 DOI: 10.7554/elife.89459.4.Peer-Reviewed Original ResearchIon occupancyIon binding sitesTerminal amineIon densitySelectivity filterLow-resolution structureProtein conformationIonsDetergent micellesPotassium channelsToxin blockVoltage-gated potassium channel Kv1.2Non-conductingStructureVoltage-gated potassium channelsPotassium channel Kv1.2Kv1.2 potassium channelChannel's outer mouthBinding sites
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