2011
Ketogenic diet in the treatment of seizures associated with hypothalamic hamartomas
Chapman K, Kim D, Rho J, Ng Y, Kerrigan J. Ketogenic diet in the treatment of seizures associated with hypothalamic hamartomas. Epilepsy Research 2011, 94: 218-221. PMID: 21377333, PMCID: PMC3161155, DOI: 10.1016/j.eplepsyres.2011.02.004.Peer-Reviewed Original ResearchConceptsHypothalamic hamartomaKetogenic dietIntrinsic epileptogenicityMultiple seizure typesKetone bodiesSurgical resectionHH tissueSpontaneous firingMedical therapyRetrospective studySeizure-freedomSeizure typesPatientsAlternative treatmentMicroelectrode recordingsHH neuronsHamartomaTissue slicesSeizuresNeuronsTreatmentResection
2003
Hypothalamic hamartomas: seven cases and review of the literature
Nguyen D, Singh S, Zaatreh M, Novotny E, Levy S, Testa F, Spencer SS. Hypothalamic hamartomas: seven cases and review of the literature. Epilepsy & Behavior 2003, 4: 246-258. PMID: 12791326, DOI: 10.1016/s1525-5050(03)00086-6.Peer-Reviewed Original ResearchConceptsSessile lesionsPrecocious pubertyDifferent surgical optionsGamma Knife surgeryRare developmental lesionIntrinsic epileptogenicityGelastic seizuresGelastic epilepsySeizure typesPartial resectionSurgical optionsHypothalamic hamartomaOpen surgeryTranscallosal approachClinical aspectsSubtemporal approachIntraventricular componentDevelopmental lesionsCognitive declineLesionsAvailable evidenceResectionSurgerySeizuresSubsequent development
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