2012
Human Laboratory Paradigms in Alcohol Research
Plebani J, Ray L, Morean M, Corbin W, MacKillop J, Amlung M, King A. Human Laboratory Paradigms in Alcohol Research. Alcohol Clinical And Experimental Research 2012, 36: 972-983. PMID: 22309888, PMCID: PMC4167612, DOI: 10.1111/j.1530-0277.2011.01704.x.Peer-Reviewed Original ResearchConceptsHuman laboratory studiesAlcohol cravingAlcohol researchHuman laboratory paradigmsMechanisms of riskField of alcoholAlcohol phenotypesNeurobehavioral mechanismsAlcohol pharmacotherapyLaboratory paradigmAlcohol effectsExperimental laboratory approachAlcohol riskNeuropharmacological effectsMedication developmentPhenotype refinementTranslational phenotypesAlcohol usersCravingTreatment responsePhenotypically distinct subtypesFindings to studiesAlcoholAlcoholic etiologyBehavioral economics
2005
Histological-hemodynamic correlation in cirrhosis—a histological classification of the severity of cirrhosis
Nagula S, Jain D, Groszmann RJ, Garcia-Tsao G. Histological-hemodynamic correlation in cirrhosis—a histological classification of the severity of cirrhosis. Journal Of Hepatology 2005, 44: 111-117. PMID: 16274836, DOI: 10.1016/j.jhep.2005.07.036.Peer-Reviewed Original ResearchConceptsHepatic venous pressure gradientPresence of CSPHSeverity of cirrhosisSeptal thicknessSmall nodularityPortal hypertensionPortal tractsBiopsy-proven cirrhosisSpecific histological parametersVenous pressure gradientDevelopment of complicationsNodule sizeHistological cirrhosisSinusoidal fibrosisAlcoholic etiologyHVPG measurementIndependent predictorsDefinitive diagnosisHistological classificationBACKGROUND/CirrhosisHistological parametersCentral veinNodularityCSPH
2004
Treatment of acute variceal bleeding: general management and prevention of infections
Garcia-Tsao G. Treatment of acute variceal bleeding: general management and prevention of infections. 2004, 233-240. DOI: 10.1007/978-94-007-1042-9_25.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsVariceal bleedingCirrhotic patientsPoor outcomePredictive factorsHepatic venous pressure gradientUpper gastrointestinal bleeding episodesActive variceal bleedingEarly recurrent bleedingAcute variceal bleedingVenous pressure gradientGastrointestinal bleeding episodesPrevention of infectionAlcoholic etiologyBleeding episodesGastrointestinal hemorrhageRecurrent bleedingRenal dysfunctionVariceal hemorrhageLiver dysfunctionEsophageal varicesUncontrolled bleedingDiagnostic endoscopyHepatocellular carcinomaBleedingPatients
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