2020
Acute Kidney Injury in Decompensated Cirrhosis Is Associated With Both Hypo‐coagulable and Hyper‐coagulable Features
Zanetto A, Rinder HM, Campello E, Saggiorato G, Deng Y, Ciarleglio M, Wilson FP, Senzolo M, Gavasso S, Bulato C, Simioni P, Garcia‐Tsao G. Acute Kidney Injury in Decompensated Cirrhosis Is Associated With Both Hypo‐coagulable and Hyper‐coagulable Features. Hepatology 2020, 72: 1327-1340. PMID: 32614088, PMCID: PMC8672302, DOI: 10.1002/hep.31443.Peer-Reviewed Original ResearchConceptsAcute kidney injuryPlasmin-antiplasmin complexDecompensated cirrhosisHemostasis assessmentVon Willebrand factorKidney injuryPlatelet functionThrombin generationPlatelet aggregationSeverity of cirrhosisMedian serum creatinineWillebrand factorLower platelet aggregationAnti-coagulant factorsImpaired platelet functionAKI resolutionHypercoagulable featuresSerum creatinineAspects of hemostasisCirrhosis patientsPlatelet countProspective studyFibrinolytic factorsCirrhosisHyperfibrinolytic state
2018
Utility and Limitations of Glycated Hemoglobin (HbA1c) in Patients with Liver Cirrhosis as Compared with Oral Glucose Tolerance Test for Diagnosis of Diabetes
Sehrawat T, Jindal A, Kohli P, Thour A, Kaur J, Sachdev A, Gupta Y. Utility and Limitations of Glycated Hemoglobin (HbA1c) in Patients with Liver Cirrhosis as Compared with Oral Glucose Tolerance Test for Diagnosis of Diabetes. Diabetes Therapy 2018, 9: 243-251. PMID: 29305791, PMCID: PMC5801248, DOI: 10.1007/s13300-017-0362-4.Peer-Reviewed Original ResearchOral glucose tolerance testDiagnosis of diabetesSeverity of cirrhosisGlucose tolerance testWorld Health OrganizationLiver cirrhosisSevere anemiaTolerance testStandard oral glucose tolerance testCTP class AGold-standard oral glucose tolerance testPrevalence of diabetesEffect of anemiaSeverity of anemiaNegative predictive valuePugh scoreChild-TurcotteOGTT resultsPatient departmentHospitalized patientsOGTT criteriaWHO criteriaResultsA totalGlycated hemoglobinCirrhosis
2005
Histological-hemodynamic correlation in cirrhosis—a histological classification of the severity of cirrhosis
Nagula S, Jain D, Groszmann RJ, Garcia-Tsao G. Histological-hemodynamic correlation in cirrhosis—a histological classification of the severity of cirrhosis. Journal Of Hepatology 2005, 44: 111-117. PMID: 16274836, DOI: 10.1016/j.jhep.2005.07.036.Peer-Reviewed Original ResearchConceptsHepatic venous pressure gradientPresence of CSPHSeverity of cirrhosisSeptal thicknessSmall nodularityPortal hypertensionPortal tractsBiopsy-proven cirrhosisSpecific histological parametersVenous pressure gradientDevelopment of complicationsNodule sizeHistological cirrhosisSinusoidal fibrosisAlcoholic etiologyHVPG measurementIndependent predictorsDefinitive diagnosisHistological classificationBACKGROUND/CirrhosisHistological parametersCentral veinNodularityCSPH
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply