2024
Validation of Metallothionein Immunohistochemistry as a Highly Sensitive Screening Test for Wilson Disease
Stokes N, Patil A, Adeyi O, Bhalla A, Brown I, Byrnes K, Calderaro J, Chen D, Chen W, Cooper C, Dhall D, Frankel W, Gooch G, Gonzalez R, Hammer S, Hale G, Lagana S, McKenzie C, Allende D, Moreira R, Nakhleh R, Nalbantoglu I, Pai R, Salomao M, Schaeffer D, Shih A, Shin J, Simoes C, Vij M, Rela M, Xue Y, Yantiss R, Sabatto B, Graham R. Validation of Metallothionein Immunohistochemistry as a Highly Sensitive Screening Test for Wilson Disease. Modern Pathology 2024, 38: 100628. PMID: 39384020, DOI: 10.1016/j.modpat.2024.100628.Peer-Reviewed Original ResearchWilson's diseaseHistological featuresRare autosomal recessive conditionChronic cholestatic diseaseProtean clinical manifestationsEvaluation of patientsAutosomal recessive conditionSensitive screening testCase of WDCost-effective screening toolRoutine histologic sectionsMedian ageNeedle biopsyCholestatic diseasesWD patientsFibrosis stageClinical manifestationsHistopathological patternsATP7B mutationsHistological patternWD diagnosisTissue specimensAssessed patientsImmunohistochemistryMasson's trichromeSimilarities and differences of interstitial lung disease associated with pathogenic variants in SFTPC and ABCA3 in adults
Diesler R, Legendre M, Si‐Mohamed S, Brillet P, Wemeau L, Manali E, Gagnadoux F, Hirschi S, Lorillon G, Reynaud‐Gaubert M, Bironneau V, Blanchard E, Bourdin A, Dominique S, Justet A, Macey J, Marchand‐Adam S, Morisse‐Pradier H, Nunes H, Papiris S, Traclet J, Traore I, Crestani B, Amselem S, Nathan N, Borie R, Cottin V, network T. Similarities and differences of interstitial lung disease associated with pathogenic variants in SFTPC and ABCA3 in adults. Respirology 2024, 29: 312-323. PMID: 38345107, DOI: 10.1111/resp.14667.Peer-Reviewed Original ResearchConceptsInterstitial lung diseaseChest Computed TomographyGround-glass opacitiesInterstitial pneumoniaFibrosing ILDsMulticentre retrospective studyConsecutive adult patientsNonspecific interstitial pneumoniaMedian FVCChest CTMedian timeRadiological patternsClinical characteristicsLung transplantationRare conditionRetrospective studyAdult patientsHistological patternComputed tomographyFollow-upPathogenic variantsLung diseaseSFTPCABCA3PatientsHistopathologic fate of resected pulmonary pure ground glass nodule: a systematic review and meta-analysis
Woo W, Kang D, Jin Y, Kipkorir V, Song S, Moon D, Shin J, Lee S. Histopathologic fate of resected pulmonary pure ground glass nodule: a systematic review and meta-analysis. Journal Of Thoracic Disease 2024, 0: 0-0. PMID: 38505083, PMCID: PMC10944737, DOI: 10.21037/jtd-23-1089.Peer-Reviewed Original ResearchMinimally invasive adenocarcinomaGround-glass nodulesAdenocarcinoma in situAtypical adenomatous hyperplasiaPure ground-glass nodulesInvasive adenocarcinomaMeta-analysisDiagnosis of invasive adenocarcinomaLung cancer screening programAggressive histologic patternCancer screening programLepidic subtypeSublobar resectionBetween-study heterogeneityHistological subtypesInvasive componentPathology reportsPathological diagnosisPooled proportionAdenomatous hyperplasiaHistological outcomesClinical outcomesHistological patternPathological characteristicsGlass nodules
2016
Immunologic Changes Implicated in the Pathogenesis of Focal Segmental Glomerulosclerosis
Kronbichler A, Leierer J, Oh J, Meijers B, Shin J. Immunologic Changes Implicated in the Pathogenesis of Focal Segmental Glomerulosclerosis. BioMed Research International 2016, 2016: 2150451. PMID: 26989679, PMCID: PMC4773535, DOI: 10.1155/2016/2150451.Peer-Reviewed Original ResearchConceptsFocal segmental glomerulosclerosisImmunological changesTGF-ss1TNF-aSegmental glomerulosclerosisTransforming growth factor-ss1End-stage renal diseaseClinical practiceTumor necrosis factor-aPathogenesis of focal segmental glomerulosclerosisDevelopment of proteinuriaB7-1Primary FSGSProfibrotic milieuTumor necrosisImmunosuppressive measuresResistant patientsRenal biopsyT cellsImmunological factorsHistological patternInterleukin-1ssRenal diseaseDisease progressionDisease onset
2014
ITMIG Consensus Statement on the Use of the WHO Histological Classification of Thymoma and Thymic Carcinoma: Refined Definitions, Histological Criteria, and Reporting
Marx A, Ströbel P, Badve SS, Chalabreysse L, Chan JK, Chen G, de Leval L, Detterbeck F, Girard N, Huang J, Kurrer MO, Lauriola L, Marino M, Matsuno Y, Molina TJ, Mukai K, Nicholson AG, Nonaka D, Rieker R, Rosai J, Ruffini E, Travis WD. ITMIG Consensus Statement on the Use of the WHO Histological Classification of Thymoma and Thymic Carcinoma: Refined Definitions, Histological Criteria, and Reporting. Journal Of Thoracic Oncology 2014, 9: 596-611. PMID: 24722150, DOI: 10.1097/jto.0000000000000154.Peer-Reviewed Original ResearchConceptsThymic carcinomaThymic epithelial tumorsB3 thymomaEpithelial tumorsInternational Thymic Malignancy Interest GroupWorld Health Organization classificationPoor interobserver reproducibilityHistological patternOrganization classificationConsensus statementHistological classificationHistological criteriaThymoma subtypesThymomaAtypical typeGrading systemInterobserver reproducibilityTumorsCarcinomaReproducibility studyRefined criteriaMorphological overlapSubtypesVariable proportions
2009
Leptospirosis pulmonary haemorrhage syndrome is associated with linear deposition of immunoglobulin and complement on the alveolar surface
Croda J, Neto A, Brasil R, Pagliari C, Nicodemo A, Duarte M. Leptospirosis pulmonary haemorrhage syndrome is associated with linear deposition of immunoglobulin and complement on the alveolar surface. Clinical Microbiology And Infection 2009, 16: 593-599. PMID: 19778300, DOI: 10.1111/j.1469-0691.2009.02916.x.Peer-Reviewed Original ResearchConceptsLeptospirosis pulmonary hemorrhage syndromePulmonary hemorrhage syndromeLPHS patientsPulmonary hemorrhageAlveolar surfaceLinear depositionUnique histological patternLife-threatening syndromeImmunoglobulin depositsTreatment regimensPathological featuresPresent studyHistological patternLung specimensLung tissueSevere diseaseAlveolar septaHuman leptospirosisLinear stainingSyndromeZoonotic infectionGranular stainingHemorrhageHeterogeneous stainingPatientsWNT5A Is a Regulator of Fibroblast Proliferation and Resistance to Apoptosis
Vuga LJ, Ben-Yehudah A, Kovkarova-Naumovski E, Oriss T, Gibson KF, Feghali-Bostwick C, Kaminski N. WNT5A Is a Regulator of Fibroblast Proliferation and Resistance to Apoptosis. American Journal Of Respiratory Cell And Molecular Biology 2009, 41: 583-589. PMID: 19251946, PMCID: PMC2778165, DOI: 10.1165/rcmb.2008-0201oc.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsApoptosisbeta CateninBlotting, WesternCase-Control StudiesCaspase 3Cell LineCell ProliferationCell SurvivalFibroblastsFibronectinsGene Expression ProfilingHumansHydrogen PeroxideIdiopathic Pulmonary FibrosisIntegrin alpha5LungMiceOligonucleotide Array Sequence AnalysisProto-Oncogene ProteinsRecombinant ProteinsReverse Transcriptase Polymerase Chain ReactionRNA InterferenceTransfectionUp-RegulationWnt ProteinsWnt-5a ProteinConceptsUsual interstitial pneumoniaNormal lung fibroblastsLung tissueLung fibroblastsFibrotic interstitial lung diseaseInterstitial lung fibrosisSpecific histopathologic patternIdiopathic pulmonary fibrosisInterstitial lung diseaseRole of Wnt5aReal-time RT-PCRQuantitative real-time RT-PCRInterstitial pneumoniaPulmonary fibrosisAutoimmune diseasesHistopathologic patternLung diseaseLung fibrosisHistological patternNormal histologyWnt/beta-catenin pathwayCanonical Wnt/beta-catenin pathwayWestern blotFibroblast proliferationBeta-catenin pathway
2007
Management of nonmelanoma skin cancer in 2007
Neville JA, Welch E, Leffell DJ. Management of nonmelanoma skin cancer in 2007. Nature Reviews Clinical Oncology 2007, 4: 462-469. PMID: 17657251, DOI: 10.1038/ncponc0883.Peer-Reviewed Original ResearchConceptsNonmelanoma skin cancerSkin cancerNew noninvasive treatmentImmune response modifiersMohs micrographic surgeryTopical chemotherapeuticsSelect tumorsHistological patternMicrographic surgerySurgical methodsConventional excisionNoninvasive optionNoninvasive treatmentTumor typesSurgeryCancerPhotodynamic therapyTreatmentCurettageMorbidityElectrodesiccationTherapyTumorsExcisionRetinoids
1979
CNS Infiltration: A Complication of Diffuse Lymphomas
Young R, Howser D, Anderson T, Jaffe E, DeVita V. CNS Infiltration: A Complication of Diffuse Lymphomas. 1979, 121-130. DOI: 10.1007/978-1-349-04285-2_11.Peer-Reviewed Original ResearchCentral nervous systemHistological patternVaried histological patternsHigh-risk populationDiffuse histological patternVaried natural historyCNS complicationsCNS recurrenceNeurological complicationsProphylactic therapySerious complicationsLymphomatous involvementRappaport classificationHodgkin's lymphomaSuccessful therapyHigh riskDistinct histologyNervous systemDiffuse lymphomaComplications
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply