2018
A Mixed Periodic Paralysis & Myotonia Mutant, P1158S, Imparts pH-Sensitivity in Skeletal Muscle Voltage-gated Sodium Channels
Ghovanloo MR, Abdelsayed M, Peters CH, Ruben PC. A Mixed Periodic Paralysis & Myotonia Mutant, P1158S, Imparts pH-Sensitivity in Skeletal Muscle Voltage-gated Sodium Channels. Scientific Reports 2018, 8: 6304. PMID: 29674667, PMCID: PMC5908869, DOI: 10.1038/s41598-018-24719-y.Peer-Reviewed Original ResearchConceptsPeriodic paralysisSkeletal muscle voltageSkeletal muscle channelopathiesHypokalemic periodic paralysisSteady-state fast inactivationLow potassium levelsAutosomal dominant mutationsEpisodic attacksIntense exercisePhysical activityMuscle channelopathiesBlood acidosisCommon triggerPotassium levelsAction potential modelingParalysisSodium channelsMuscular contractionSkeletal muscleMyotoniaPhenotype correlationLate currentPatientsExtracellular pHFast inactivationImpaired corticomuscular and interhemispheric cortical beta oscillation coupling in amyotrophic lateral sclerosis
Proudfoot M, van Ede F, Quinn A, Colclough G, Wuu J, Talbot K, Benatar M, Woolrich M, Nobre A, Turner M. Impaired corticomuscular and interhemispheric cortical beta oscillation coupling in amyotrophic lateral sclerosis. Clinical Neurophysiology 2018, 129: 1479-1489. PMID: 29678369, DOI: 10.1016/j.clinph.2018.03.019.Peer-Reviewed Original ResearchConceptsALS patientsHealthy controlsCorticomuscular coherenceGene carriersAsymptomatic gene carriersBeta-band corticomuscular coherenceMotor cortexTherapeutic efficacyDisease mimicsMotor system dysfunctionSystem dysfunctionWhole-head magnetoencephalographyPatientsForce productionNeuropathyPrimary motor cortexBeta rhythmsBeta bandCortical hemisphereStructural MRICortexNeural activityMuscular contractionInterhemispheric communicationCorticomuscular
2001
Neurotransmitters and Neurohormones
B.Levitan I, Kaczmarek L. Neurotransmitters and Neurohormones. 2001, 223-252. DOI: 10.1093/oso/9780195145236.003.0010.Peer-Reviewed Original Research
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