2023
99mTc/123I Dual-Radionuclide Correction for Self-Scatter, Down-Scatter, and Tailing Effect for a CZT SPECT With Varying Tracer Distributions
Velo A, Fan P, Xie H, Chen X, Boutagy N, Feher A, Sinusas A, Ljungberg M, Liu C. 99mTc/123I Dual-Radionuclide Correction for Self-Scatter, Down-Scatter, and Tailing Effect for a CZT SPECT With Varying Tracer Distributions. IEEE Transactions On Radiation And Plasma Medical Sciences 2023, 7: 839-850. PMID: 38745858, PMCID: PMC11090119, DOI: 10.1109/trpms.2023.3297443.Peer-Reviewed Original Research
2018
Monte Carlo dosimetry modeling of focused kV x‐ray radiotherapy of eye diseases with potential nanoparticle dose enhancement
Yan H, Ma X, Sun W, Mendez S, Stryker S, Starr‐Baier S, Delliturri G, Zhu D, Nath R, Chen Z, Roberts K, MacDonald CA, Liu W. Monte Carlo dosimetry modeling of focused kV x‐ray radiotherapy of eye diseases with potential nanoparticle dose enhancement. Medical Physics 2018, 45: 4720-4733. PMID: 30133705, DOI: 10.1002/mp.13144.Peer-Reviewed Original ResearchConceptsX-ray beamMC simulation programEye plaque treatmentCentral axis depth doseMC simulationsDose distributionBeam focusingEye Physics plaquesPhantom irradiationDose enhancementEnergy spectrumDepth doseLens modelingDosimetry modelingPhotoelectric absorptionKV rangeKV X-ray beamsBeamEBT3 filmSimulation programEnergy regimeModelingX-ray techniquesHalf maximumMore flexibility
2017
The Chandra COSMOS Legacy Survey: Energy Spectrum of the Cosmic X-Ray Background and Constraints on Undetected Populations
Cappelluti N, Li Y, Ricarte A, Agarwal B, Allevato V, Ananna T, Ajello M, Civano F, Comastri A, Elvis M, Finoguenov A, Gilli R, Hasinger G, Marchesi S, Natarajan P, Pacucci F, Treister E, Urry C. The Chandra COSMOS Legacy Survey: Energy Spectrum of the Cosmic X-Ray Background and Constraints on Undetected Populations. The Astrophysical Journal 2017, 837: 19. DOI: 10.3847/1538-4357/aa5ea4.Peer-Reviewed Original ResearchSpectral index γBlack holesCosmic X-ray background spectrumIndex γCosmic X-ray backgroundX-ray background spectrumX-ray-detected sourcesStar-forming galaxiesActive galactic nucleiKeV energy bandX-ray backgroundEarly black holesLow-metallicity environmentsX-ray sourcesUndetected galaxiesExtragalactic componentGalactic nucleiChandra observationsFaint galaxiesHard spectrumUnresolved sourcesLegacy SurveyPower lawEnergy spectrumThermal plasmaA measurement-based generalized source model for Monte Carlo dose simulations of CT scans
Ming X, Feng Y, Liu R, Yang C, Zhou L, Zhai H, Deng J. A measurement-based generalized source model for Monte Carlo dose simulations of CT scans. Physics In Medicine And Biology 2017, 62: 1759-1776. PMID: 28079526, PMCID: PMC5857954, DOI: 10.1088/1361-6560/aa5911.Peer-Reviewed Original ResearchConceptsMonte Carlo dose simulationsGeneralized source modelEnergy spectrumFluence distributionDose profilesCentral axis percent depth dose curvePercent depth dose curvesDose simulationsDepth dose curvesMonte Carlo user codeSource distributionBeam inputDose curvesFilm measurementsCTDI phantomCT scannerOutput factorsAbsolute dose comparisonsMonte Carlo simulationsDose distributionSource modelCarlo simulationsCircular sourceGE LightspeedScanner specifications
2015
Scatter and crosstalk corrections for 99mTc/123I dual‐radionuclide imaging using a CZT SPECT system with pinhole collimators
Fan P, Hutton BF, Holstensson M, Ljungberg M, Pretorius P, Prasad R, Ma T, Liu Y, Wang S, Thorn SL, Stacy MR, Sinusas AJ, Liu C. Scatter and crosstalk corrections for 99mTc/123I dual‐radionuclide imaging using a CZT SPECT system with pinhole collimators. Medical Physics 2015, 42: 6895-6911. PMID: 26632046, DOI: 10.1118/1.4934830.Peer-Reviewed Original ResearchConceptsDual-radionuclide imagingCrosstalk correction methodTEW methodLine source experimentDefect contrastSource experimentsMonte Carlo simulationsIncomplete charge collectionCadmium zinc telluride detectorsLow-energy tailImaging systemCarlo simulationsPinhole collimatorCardiac SPECT systemEnergy tailDetector effectsEnergy spectrumPoint source measurementsSPECT systemCZT detectorsTriple energy window (TEW) methodScatter modelDedicated cardiac SPECT systemsCorrection methodCrosstalk correctionFast Biological Modeling for Voxel-based Heavy Ion Treatment Planning Using the Mechanistic Repair-Misrepair-Fixation Model and Nuclear Fragment Spectra
Kamp F, Cabal G, Mairani A, Parodi K, Wilkens JJ, Carlson DJ. Fast Biological Modeling for Voxel-based Heavy Ion Treatment Planning Using the Mechanistic Repair-Misrepair-Fixation Model and Nuclear Fragment Spectra. International Journal Of Radiation Oncology • Biology • Physics 2015, 93: 557-568. PMID: 26460998, DOI: 10.1016/j.ijrobp.2015.07.2264.Peer-Reviewed Original ResearchConceptsRelative biological effectivenessCarbon ion therapyCarbon ionsIon therapyHeavy ion treatment planningMonte Carlo code FLUKAPrimary carbon ionsCarbon ion energyRadiation therapy beamsRBE valuesCarbon ion treatment plansRelevant RBE valuesRMF predictionsHeavy ionsIon energyDouble-strand break (DSB) yieldsRMF modelEnergy spectrumTherapy beamsSecondary fragmentsMonte Carlo damage simulationNuclear fragmentsBiological optimizationBiological effectivenessRBE predictions
2013
SU‐E‐T‐25: Investigating the Impact of Polymer‐Coating On the Dosimetric Characteristics of a 103Pd Brachytherapy Source Using Photon Spectroscopy
Chen Z, Kim J, Nath R. SU‐E‐T‐25: Investigating the Impact of Polymer‐Coating On the Dosimetric Characteristics of a 103Pd Brachytherapy Source Using Photon Spectroscopy. Medical Physics 2013, 40: 208-208. DOI: 10.1118/1.4814459.Peer-Reviewed Original ResearchPhoton energy spectrumHigh-purity germaniumDosimetric characteristicsEnergy spectrumLow-energy brachytherapy sourcesDose-rate constantDose rate constantPd-103Photon spectroscopyBrachytherapy sourcesPhoton spectrometerPd-103 seedsDosimetric propertiesBrachytherapy seedsPhotonic characteristicsDosimetry dataPhotonsSeed modelSpectraBrachytherapyHigh-resolutionDosimetricallyDosimetrySeed migrationConstantSU‐E‐T‐100: The Influence Edge Electrons in Small Fields: Emphasis by the Difference of Copper‐Cerrobend Cutout
Chu A, Deng J, Feng W, Chen Z, Ahmad M, Nath R. SU‐E‐T‐100: The Influence Edge Electrons in Small Fields: Emphasis by the Difference of Copper‐Cerrobend Cutout. Medical Physics 2013, 40: 226-226. DOI: 10.1118/1.4814535.Peer-Reviewed Original ResearchCerrobend cutoutsEdge electronsFilm dosimetry techniquesSurface of phantomMonte Carlo calculationsVarian acceleratorPDD curvesElectron scatteringDose profilesDose outputElectron energyEnergy spectrumPrimary electronsDosimetry techniquesElectron beamBeam-qualityPhoton transmissionMonte Carlo simulationsSmall fieldsEdge scatteringChamber measurementsNarrow widthBremsstrahlungCerrobendElectron
2010
Novel Scatter Compensation of List-Mode PET Data Using Spatial and Energy Dependent Corrections
Guérin B, Fakhri G. Novel Scatter Compensation of List-Mode PET Data Using Spatial and Energy Dependent Corrections. IEEE Transactions On Medical Imaging 2010, 30: 759-773. PMID: 21118770, PMCID: PMC3120772, DOI: 10.1109/tmi.2010.2095025.Peer-Reviewed Original ResearchConceptsScattered coincidencesEnergy resolutionE-pdfNCAT phantomDependent correctionsEnergy of individual photonsScatter correctionEnergy dependent correctionsEnergy probability density functionScatter correction schemeTotal energy spectrumList-mode acquisitionEnergy informationPositron emission tomography dataActivity distribution estimationScatter sinogramIndividual photonsEnergy spectrumCylindrical phantomEnergy distributionMonte Carlo simulationsScattering approachPhotonsScatteringScattering componentMO‐EE‐A1‐04: A Generalized Dose‐Rate Constant Formalism for Brachytherapy Sources Emitting Anisotropic Photon Energy Spectrum
Chen Z, Nath R. MO‐EE‐A1‐04: A Generalized Dose‐Rate Constant Formalism for Brachytherapy Sources Emitting Anisotropic Photon Energy Spectrum. Medical Physics 2010, 37: 3347-3347. DOI: 10.1118/1.3469082.Peer-Reviewed Original ResearchDose deposition kernelPhoton energy spectrumEnergy spectrumBrachytherapy sourcesGeneral formalismPrimary photonsTransverse bisectorPhoton sourcesLow-energy brachytherapy sourcesMass energy absorption coefficientsDose-rate constantContribution of scattered photonsInterstitial brachytherapy sourcesAngular energy spectraIsotropic energy spectrumScattered photonsRadioactive sourcesDosimetry parametersPhotonsEnergy EPhoton emissionDose-rateFormalismSpectraBrachytherapy
2008
Realistic PET Monte Carlo Simulation with Pixelated Block Detectors, Light Sharing, Random Coincidences and Dead-Time Modeling
Guérin B, Fakhri G. Realistic PET Monte Carlo Simulation with Pixelated Block Detectors, Light Sharing, Random Coincidences and Dead-Time Modeling. IEEE Transactions On Nuclear Science 2008, 55: 942-952. PMID: 19079776, PMCID: PMC2600659, DOI: 10.1109/tns.2008.924064.Peer-Reviewed Original ResearchBlock detectorsDiscovery STRandom coincidencesSimSET softwareMonte Carlo transport codeElectronics dead-timeNEMA NU 2Detector dead-timeDead-timeMonte Carlo simulation softwarePositron emission tomography scannerSimulated spatial resolutionPET modelingSpatial resolutionWhole scannerCoincidence spectraPhoton interactionsEnergy spectrumNU 2Light sharingTransport codeSingles ratesCrystal elementsDead-time modelMonte Carlo simulations
2007
SU‐FF‐T‐82: Angular Distribution of Photon Energy Spectra Emitted by Low‐Energy Interstitial Brachytherapy Sources
Chen Z, Khan S, Nath R. SU‐FF‐T‐82: Angular Distribution of Photon Energy Spectra Emitted by Low‐Energy Interstitial Brachytherapy Sources. Medical Physics 2007, 34: 2419-2420. DOI: 10.1118/1.2760734.Peer-Reviewed Original ResearchLow-energy interstitial brachytherapy sourcesPhoton energy spectrumInterstitial brachytherapy sourcesBrachytherapy sourcesEnergy spectrumTitanium encapsulationAngular distributionsPhoton fluenceLow-energy brachytherapy sourcesDetermination of dose distributionsLow energy photon spectrometrySource-to-detector distanceHigh-purity germanium detectorLow-energy sourcesSpectral hardeningPhoton spectrometerDose distributionGermanium detectorEmitted photonsFluence distributionSource holderPhoton spectrometryBrachytherapy treatmentLow energySpatial isotropyTH‐E‐AUD‐01: Photon Energy Spectrum Emitted by a Novel Polymer‐Encapsulated 103Pd Source and Its Effect On the Dose Rate Constant
Khan S, Chen Z, Nath R. TH‐E‐AUD‐01: Photon Energy Spectrum Emitted by a Novel Polymer‐Encapsulated 103Pd Source and Its Effect On the Dose Rate Constant. Medical Physics 2007, 34: 2652-2652. DOI: 10.1118/1.2761765.Peer-Reviewed Original ResearchDose-rate constantRelative energy spectrumEnergy spectrumHigh-resolution germanium spectrometerAir kerma strengthDose rate constantPhoton energy spectrumMeasured energy spectraLow-energy photonsTitanium encapsulationSpectral hardeningClinical dosimetryGermanium spectrometerDosimetry parametersPhoton spectrometryValues of LPhotonsExperimental uncertaintySource geometryConsensus valueDosimetrySpectraConstantIndependent determinationRadial direction
2005
Realistic Monte Carlo PET Simulation with Pixellated Block Detectors, Light Sharing and Randoms Modeling
Guérin B, Fakhri G. Realistic Monte Carlo PET Simulation with Pixellated Block Detectors, Light Sharing and Randoms Modeling. 2005, 3: 1563-1567. DOI: 10.1109/nssmic.2005.1596617.Peer-Reviewed Original ResearchPET scannerBlock detectorsPhoton transportRandom coincidencesSimSET softwareMonte Carlo transport codeNEMA NU 2Model of photon transportEnergy weighted averageModel photon transportLight-sharingEnergy spectrumNU 2Light sharingTransport codeCrystal elementsMonte Carlo simulationsPET simulationsVery good agreementInteraction pointPET acquisitionDetection crystalAttenuation distributionDetectorCarlo simulations
2003
Commissioning 6 MV photon beams of a stereotactic radiosurgery system for Monte Carlo treatment planning
Deng J, Ma C, Hai J, Nath R. Commissioning 6 MV photon beams of a stereotactic radiosurgery system for Monte Carlo treatment planning. Medical Physics 2003, 30: 3124-3134. PMID: 14713079, DOI: 10.1118/1.1624753.Peer-Reviewed Original ResearchConceptsMonte Carlo dose calculationsMonte Carlo treatment planningBeam phase spaceOutput factorsCentral axis depth dose curvesDose profilesMonte Carlo treatmentMeasurement dataMultiple source modelCyberknife stereotactic radiosurgery systemPhase spaceMV photon beamDepth dose curvesDose calculationsSource modelStereotactic radiosurgery systemFluence distributionStandard measurement dataSource distributionPhoton beamsAxis distanceEnergy spectrumCollimator sizeDose curvesAveraging effect
2001
Derivation of electron and photon energy spectra from electron beam central axis depth dose curves
Deng J, Jiang S, Pawlicki T, Li J, Ma C. Derivation of electron and photon energy spectra from electron beam central axis depth dose curves. Physics In Medicine And Biology 2001, 46: 1429-1449. PMID: 11384063, DOI: 10.1088/0031-9155/46/5/308.Peer-Reviewed Original ResearchConceptsPhoton energy spectrumDepth dose curvesCentral axis depth dose curvesPhase-space simulationsElectron beamEnergy spectrumDose curvesElectron beam dose calculationsLinear accelerator treatment headCentral axis percentage depth-dose (PDD) curvesPercentage depth dose curvesDerivation of electronPhase space dataClinical electron beamsMeV electron beamSpace simulationTreatment headPDD curvesDose profilesElectronsBeamCorresponding spectraPhotonsDose calculationsSpectra
2000
Photon beam characterization and modelling for Monte Carlo treatment planning
Deng J, Jiang S, Kapur A, Li J, Pawlicki T, Ma C. Photon beam characterization and modelling for Monte Carlo treatment planning. Physics In Medicine And Biology 2000, 45: 411-427. PMID: 10701512, DOI: 10.1088/0031-9155/45/2/311.Peer-Reviewed Original ResearchConceptsOriginal phase spacePhase spaceMonte Carlo calculationsPhoton jawsCarlo calculationsMonte Carlo treatment planningSource-surface distanceVarian Clinac 2100CPhase space filesPrimary collimatorMultiple source modelPhoton beamsPlanar fluenceAngular distributionsMV photon beamClinac 2100CField sizeSource modelBeam characterizationDose distributionHeterogeneous phantomsGood agreementBeam characteristicsFlattening filterEnergy spectrum
1998
Artificial neural network as a tool to compensate for scatter and attenuation in radionuclide imaging.
Maksud P, Fertil B, Rica C, El Fakhri G, Aurengo A. Artificial neural network as a tool to compensate for scatter and attenuation in radionuclide imaging. Journal Of Nuclear Medicine 1998, 39: 735-45. PMID: 9544691.Peer-Reviewed Original ResearchConceptsEnergy spectrumCompton scatteringRadioactive sourcesImages of radioactive sourcesScatter correctionArtificial neural networkNeural networkNumerical Monte Carlo simulationsMonte Carlo simulationsPelvis scansIncident photonsMultilayer neural networkProjection imagesScatteringComptonCarlo simulationsDiffusion mediaSource distributionSpectrum acquisitionEnergyGeometric sourcesHomogeneous mediumCorrectionSpectraNetwork
1992
Estimation of primary plus small angle scatter in scintigrams using two photopeak energy windows and a linear model
Penney B, Haynor D, King M, Byrne C, Hademenos G, Rajeevan N. Estimation of primary plus small angle scatter in scintigrams using two photopeak energy windows and a linear model. 1992, 998-1000 vol.2. DOI: 10.1109/nssmic.1992.301454.Peer-Reviewed Original ResearchPhotopeak energy windowScattering componentContrast-detail phantomSmall-angle scatteringEnergy windowEnergy spectrumScattered photonsAngle scatteringPoint spread functionQuantitative accuracyImage contrastSpread functionQuantitative errorsNo significant changesIncreased contrastPhotonsScintigraphic imagesPhantomDetection index
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