2021
Leucine-Rich α-2-Glycoprotein 1 Suppresses Endothelial Cell Activation Through ADAM10-Mediated Shedding of TNF-α Receptor
Pang K, Ghim M, Liu C, Tay H, Fhu C, Chia R, Qiu B, Sarathchandra P, Chester A, Yacoub M, Wilkinson F, Weston R, Warboys C, Hou H, Weinberg P, Wang X. Leucine-Rich α-2-Glycoprotein 1 Suppresses Endothelial Cell Activation Through ADAM10-Mediated Shedding of TNF-α Receptor. Frontiers In Cell And Developmental Biology 2021, 9: 706143. PMID: 34291056, PMCID: PMC8288075, DOI: 10.3389/fcell.2021.706143.Peer-Reviewed Original ResearchTumor necrosis factor receptor 1Critical limb ischemiaSera of patientsEndothelial activationEndothelial cellsLRG1 expressionElevated serum concentrationsPotential therapeutic roleLeucine-Rich αTumor necrosis factorTNF-α receptorWild-type miceEndothelial cell activationNecrosis factor receptor 1Role of LRG1NF-κB activationNF-κB signalingFactor receptor 1STNFR1 concentrationCLI patientsLimb ischemiaSerum concentrationsHealthy controlsInflammatory diseasesTherapeutic role
1984
Hypercalcemia associated with immunoreactive parathyroid hormone in a malignant rhabdoid tumor of the kidney (Rhabdoid Wilms' tumor)
Mayes L, Kasselberg AG, Roloff J, Lukens J. Hypercalcemia associated with immunoreactive parathyroid hormone in a malignant rhabdoid tumor of the kidney (Rhabdoid Wilms' tumor). Cancer 1984, 54: 882-884. PMID: 6331631, DOI: 10.1002/1097-0142(19840901)54:5<882::aid-cncr2820540521>3.0.co;2-n.Peer-Reviewed Original ResearchConceptsImmunoreactive parathyroid hormoneParathyroid hormoneRhabdoid tumorElevated serum concentrationsNormal parathyroid glandsMalignant rhabdoid tumorMetabolic complicationsSevere hypercalcemiaMetastatic diseaseSerum concentrationsParathyroid glandsSkeletal involvementImmunohistologic demonstrationTumor variantsHypercalcemiaTumorsTumor cellsHormoneKidneyComplicationsDisease
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply