2022
Correlation of circulating tumor DNA (ctDNA) with clinical outcomes in appendiceal cancers (AC).
Kothary V, Eng O, Polite B, Liao C, Catenacci D, Dhiman A, Turaga K, Shergill A. Correlation of circulating tumor DNA (ctDNA) with clinical outcomes in appendiceal cancers (AC). Journal Of Clinical Oncology 2022, 40: 29-29. DOI: 10.1200/jco.2022.40.4_suppl.029.Peer-Reviewed Original ResearchAppendiceal cancerCEA levelsDisease courseMedian duration to recurrenceClinical evidence of recurrenceHeterogeneous group of rare tumorsGroup of rare tumorsDuration to recurrenceConventional tumor markersElevated CEA levelsHigh-grade pathologyEvidence of recurrenceResponse to therapyRecurrence risk predictionRare tumorCtDNA testingMedian durationTumor DNAPositive CEATumor markersInitial treatmentClinical outcomesProspective studyInstitutional experienceClinical evidence
2006
Predictors of Recurrence in Patients With T2 and Early T3, N0 Adenocarcinoma of the Rectum Treated by Surgery Alone
Nissan A, Stojadinovic A, Shia J, Hoos A, Guillem J, Klimstra D, Cohen A, Minsky B, Paty P, Wong W. Predictors of Recurrence in Patients With T2 and Early T3, N0 Adenocarcinoma of the Rectum Treated by Surgery Alone. Journal Of Clinical Oncology 2006, 24: 4078-4084. PMID: 16943525, DOI: 10.1200/jco.2006.06.2968.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaAdultAgedAged, 80 and overCarcinoembryonic AntigenFemaleFollow-Up StudiesHumansLymphatic MetastasisMaleMiddle AgedNeoplasm InvasivenessNeoplasm Recurrence, LocalNeoplasm StagingPredictive Value of TestsProspective StudiesRectal NeoplasmsRisk AssessmentRisk FactorsSurvival AnalysisConceptsDisease-specific survivalPredictors of recurrenceN0 rectal cancerPelvic recurrenceRectal cancerLymphovascular invasionFive-year disease-specific survivalFollow-upPreoperative serum carcinoembryonic antigenTreatment of rectal cancerAssociated with adverse outcomesImproved overall survivalDisease-free survivalElevated CEA levelsMedian Follow-UpReduce local recurrenceSerum carcinoembryonic antigenTreated by surgeryStudy end pointProspective computerized databaseComplete follow-upGroup of patientsEnhance treatment selectionIncidence of PRNeoadjuvant radiotherapy
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