Atopic Dermatitis Is an IL-13–Dominant Disease with Greater Molecular Heterogeneity Compared to Psoriasis
Tsoi L, Rodriguez E, Degenhardt F, Baurecht H, Wehkamp U, Volks N, Szymczak S, Swindell W, Sarkar M, Raja K, Shao S, Patrick M, Gao Y, Uppala R, Perez White B, Getsios S, Harms P, Maverakis E, Elder J, Franke A, Gudjonsson J, Weidinger S. Atopic Dermatitis Is an IL-13–Dominant Disease with Greater Molecular Heterogeneity Compared to Psoriasis. Journal Of Investigative Dermatology 2019, 139: 1480-1489. PMID: 30641038, PMCID: PMC6711380, DOI: 10.1016/j.jid.2018.12.018.Peer-Reviewed Original ResearchConceptsTranscriptomic studiesPaired-end readsRNA sequencing samplesPathophysiology of ADPaired-endHigh-resolution viewStudies of ADAD transcriptomeDrug target predictionRNA sequencingLong noncoding RNAsRNA samplesDysregulated genesNoncoding RNAsRNAPsoriasis transcriptomeTranscriptomeCellular featuresGenesMolecular heterogeneityDisease heterogeneityTranslational impactIL-4 expressionAD skinGlobal architecture
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply