2024
π-HuB: the proteomic navigator of the human body
He F, Aebersold R, Baker M, Bian X, Bo X, Chan D, Chang C, Chen L, Chen X, Chen Y, Cheng H, Collins B, Corrales F, Cox J, E W, Van Eyk J, Fan J, Faridi P, Figeys D, Gao G, Gao W, Gao Z, Goda K, Goh W, Gu D, Guo C, Guo T, He Y, Heck A, Hermjakob H, Hunter T, Iyer N, Jiang Y, Jimenez C, Joshi L, Kelleher N, Li M, Li Y, Lin Q, Liu C, Liu F, Liu G, Liu Y, Liu Z, Low T, Lu B, Mann M, Meng A, Moritz R, Nice E, Ning G, Omenn G, Overall C, Palmisano G, Peng Y, Pineau C, Poon T, Purcell A, Qiao J, Reddel R, Robinson P, Roncada P, Sander C, Sha J, Song E, Srivastava S, Sun A, Sze S, Tang C, Tang L, Tian R, Vizcaíno J, Wang C, Wang C, Wang X, Wang X, Wang Y, Weiss T, Wilhelm M, Winkler R, Wollscheid B, Wong L, Xie L, Xie W, Xu T, Xu T, Yan L, Yang J, Yang X, Yates J, Yun T, Zhai Q, Zhang B, Zhang H, Zhang L, Zhang L, Zhang P, Zhang Y, Zheng Y, Zhong Q, Zhu Y. π-HuB: the proteomic navigator of the human body. Nature 2024, 636: 322-331. PMID: 39663494, DOI: 10.1038/s41586-024-08280-5.Peer-Reviewed Original ResearchConnecticut Implements a Team-Based Approach to Cardiovascular Disease Prevention Using Community Health Workers and Mobile Medical Devices
Griffin A, Ogazi C, Vozzolo C, Davis K, Baker R. Connecticut Implements a Team-Based Approach to Cardiovascular Disease Prevention Using Community Health Workers and Mobile Medical Devices. Journal Of Public Health Management And Practice 2024, 30: s124-s126. PMID: 39041747, DOI: 10.1097/phh.0000000000001939.Peer-Reviewed Original ResearchConceptsCommunity health workersRisk reduction counselingHealth workersReduction counselingCervical cancer screening servicesSocial determinants of healthCancer screening servicesDeterminants of healthCardiovascular disease risk assessmentService access barriersHealth Action PlanTeam-based approachDeliver breastHealth coachingScreening servicesHealthcare accessCommunity settingsDisease risk assessmentOutreach sessionsAccess barriersClinical servicesPrevention programsConduct outreachTeam-basedScreening assessment
2022
Effectiveness of a community health worker-delivered care intervention for hypertension control in Uganda: study protocol for a stepped wedge, cluster randomized control trial
Ingenhoff R, Nandawula J, Siddharthan T, Ssekitoleko I, Munana R, Bodnar B, Weswa I, Kirenga B, Mutungi G, van der Giet M, Kalyesubula R, Knauf F. Effectiveness of a community health worker-delivered care intervention for hypertension control in Uganda: study protocol for a stepped wedge, cluster randomized control trial. Trials 2022, 23: 440. PMID: 35610712, PMCID: PMC9128241, DOI: 10.1186/s13063-022-06403-9.Peer-Reviewed Original ResearchConceptsCommunity health workersNon-communicable diseasesUncontrolled hypertensionBlood pressureCardiovascular disease risk assessmentHealthy lifestyle counselingMonthly household visitsBlood pressure controlSub-Saharan African settingPatient-related factorsPrimary care levelStepped-wedge clusterMedical treatment outcomeMajority of LMICsMulti-component interventionDisease risk assessmentNCD clinicsHypertension controlHypertensive patientsLifestyle counselingAdult patientsHTN managementMiddle-income countriesMedication adherenceEntire cohort
2021
On cross-ancestry cancer polygenic risk scores
Fritsche L, Ma Y, Zhang D, Salvatore M, Lee S, Zhou X, Mukherjee B. On cross-ancestry cancer polygenic risk scores. PLOS Genetics 2021, 17: e1009670. PMID: 34529658, PMCID: PMC8445431, DOI: 10.1371/journal.pgen.1009670.Peer-Reviewed Original ResearchConceptsPolygenic risk scoresGenome-wide association studiesProstate cancer polygenic risk scoresPolygenic risk score distributionRecruitment of diverse participantsAncestry groupsPolygenic risk score methodsRisk scoreNon-genetic risk factorsElectronic health recordsBreast cancer casesHealth recordsUK BiobankGWAS effortsDisease risk assessmentCancer casesAssociation studiesGenetic dataEuropean ancestryPersonalized risk stratificationSummary statisticsRisk factorsAncestryDiverse participantsField of cancer
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