2024
Predicting response to non-selective beta-blockers with liver–spleen stiffness and heart rate in patients with liver cirrhosis and high-risk varices
Giuffrè M, Dupont J, Visintin A, Masutti F, Monica F, You K, Shung D, Crocè L. Predicting response to non-selective beta-blockers with liver–spleen stiffness and heart rate in patients with liver cirrhosis and high-risk varices. Hepatology International 2024, 19: 460-471. PMID: 38664292, PMCID: PMC12003444, DOI: 10.1007/s12072-024-10649-7.Peer-Reviewed Original ResearchHigh-risk varicesHepatic venous pressure gradientLiver stiffnessLiver cirrhosisSpleen stiffnessVariceal gradeHeart rateCohort of cirrhotic patientsNon-selective beta-blockersPercentual decreaseAssessed therapeutic responseMultivariate modelVenous pressure gradientCut-off valueOptimal cut-offAssociated with better predictionNSBB treatmentPrimary prophylaxisHemorrhagic episodesCirrhotic patientsTherapeutic responseBeta-blockersNSBBTreatment initiationProspective study
2017
Hepatic vein pressure predicts GFR in cirrhotic patients with hemodynamic kidney dysfunction
Desai N, Neugarten J, Dominguez M, Golestaneh L. Hepatic vein pressure predicts GFR in cirrhotic patients with hemodynamic kidney dysfunction. Physiological Reports 2017, 5: e13301. PMID: 28611152, PMCID: PMC5471440, DOI: 10.14814/phy2.13301.Peer-Reviewed Original ResearchConceptsHepatic vein pressureTransjugular intrahepatic portosystemic shuntEnd-stage renal diseaseParenchymal kidney diseaseChronic kidney diseaseVein pressureRenal diseaseKidney diseaseCirrhotic patientsUltrasound evidenceCohort of cirrhotic patientsLiver diseaseIntrahepatic portosystemic shuntIntra-abdominal hypertensionPercentage of patientsAssociated with eGFRIntra-abdominal pressureChart reviewLiver failureKidney dysfunctionPortosystemic shuntMultivariate linear regressionEGFRPatientsProteinuria
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