2024
Predicting response to non-selective beta-blockers with liver–spleen stiffness and heart rate in patients with liver cirrhosis and high-risk varices
Giuffrè M, Dupont J, Visintin A, Masutti F, Monica F, You K, Shung D, Crocè L. Predicting response to non-selective beta-blockers with liver–spleen stiffness and heart rate in patients with liver cirrhosis and high-risk varices. Hepatology International 2024, 19: 460-471. PMID: 38664292, PMCID: PMC12003444, DOI: 10.1007/s12072-024-10649-7.Peer-Reviewed Original ResearchHigh-risk varicesHepatic venous pressure gradientLiver stiffnessLiver cirrhosisSpleen stiffnessVariceal gradeHeart rateCohort of cirrhotic patientsNon-selective beta-blockersPercentual decreaseAssessed therapeutic responseMultivariate modelVenous pressure gradientCut-off valueOptimal cut-offAssociated with better predictionNSBB treatmentPrimary prophylaxisHemorrhagic episodesCirrhotic patientsTherapeutic responseBeta-blockersNSBBTreatment initiationProspective study
2020
A window into portal hemodynamics in adult fontan patients?
Simmons MA, Revzin M, To U, Liapakis A, Fahey J, Elder RW. A window into portal hemodynamics in adult fontan patients? International Journal Of Cardiology 2020, 323: 61-64. PMID: 32979426, DOI: 10.1016/j.ijcard.2020.09.047.Peer-Reviewed Original ResearchConceptsAdult Fontan patientsFontan patientsSpleen stiffnessCongenital heart diseaseLiver stiffnessShear wave elastographyControl patientsPortal hemodynamicsLiver diseaseHeart diseaseFontan-associated liver diseaseLimited subgroup analysisPortal venous hemodynamicsAssociated liver diseasePassive hepatic congestionUltrasound shear wave elastographyFontan circulationStudy cohortHealthy patientsHepatic congestionVenous hemodynamicsSubgroup analysisLiver fibrosisHealthy controlsPatients
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