2020
From Chickens to Humans: The Importance of Peptide Repertoires for MHC Class I Alleles
Kaufman J. From Chickens to Humans: The Importance of Peptide Repertoires for MHC Class I Alleles. Frontiers In Immunology 2020, 11: 601089. PMID: 33381122, PMCID: PMC7767893, DOI: 10.3389/fimmu.2020.601089.Peer-Reviewed Original ResearchConceptsKiller immunoglobulin-like receptorsMajor histocompatibility complexPeptide motifsClass I moleculesCytotoxic T lymphocytesCell surfaceChicken major histocompatibility complexClass I allelesBinding peptidesI moleculesNatural killerClassical class I moleculesResistance to infectious diseasesMultigene familyRepertoire of bound peptidesI allelesThymus-derived (T) cellsReceptor-ligand interactionsNK cell functionImmunoglobulin-like receptorsPeptide-bindingMajor histocompatibility complex class I allelePeptide repertoireAllelesMHC-I molecules
2018
An Invariant Arginine in Common with MHC Class II Allows Extension at the C-Terminal End of Peptides Bound to Chicken MHC Class I
Xiao J, Xiang W, Zhang Y, Peng W, Zhao M, Niu L, Chai Y, Qi J, Wang F, Qi P, Pan C, Han L, Wang M, Kaufman J, Gao G, Liu W. An Invariant Arginine in Common with MHC Class II Allows Extension at the C-Terminal End of Peptides Bound to Chicken MHC Class I. The Journal Of Immunology 2018, 201: 3084-3095. PMID: 30341185, DOI: 10.4049/jimmunol.1800611.Peer-Reviewed Original ResearchConceptsClassical class I moleculesC-terminusNonmammalian vertebratesChicken MHC class IC-terminal endExpressed class I moleculeClass I moleculesPeptide-binding groovePeptides to T lymphocytesJawed vertebratesClass II moleculesArg residuesChicken MHCI moleculesMHC class I allelesRepertoire of peptidesVertebratesPeptide C-terminusII moleculesMammalsClassical class II moleculesClass I allelesPeptideArgI alleles
1992
Different features of the MHC class I heterodimer have evolved at different rates. Chicken B-F and beta 2-microglobulin sequences reveal invariant surface residues.
Kaufman J, Andersen R, Avila D, Engberg J, Lambris J, Salomonsen J, Welinder K, Skjødt K. Different features of the MHC class I heterodimer have evolved at different rates. Chicken B-F and beta 2-microglobulin sequences reveal invariant surface residues. The Journal Of Immunology 1992, 148: 1532-46. PMID: 1538136, DOI: 10.4049/jimmunol.148.5.1532.Peer-Reviewed Original ResearchConceptsPatches of invariant residuesAlpha 3 domainTurkey beta 2mChicken alpha 1Structurally homologous domainsExpressed class I moleculeMHC class I heterodimersSurface residuesAlpha 3Interdomain contact sitesBeta 2 domainClassical class I moleculesAmino acid compositionSmall exonsVertebrate homologsCDNA clonesAllelic residuesInvariant residuesHomology domainCDNA sequenceAlpha 2 domainsClass I moleculesContact sitesCytoplasmic regionExtracellular domain
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